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2,4-Dihydroxybenzophenone

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Identification
Molecular formula
C14H10O4
CAS number
131-53-3
IUPAC name
(2-hydroxy-4-methoxy-phenyl)-(2-hydroxyphenyl)methanone
State
State

2,4-Dihydroxybenzophenone is typically a solid at room temperature. It usually presents as fine yellow crystals and is stable under normal conditions.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
319.10
Boiling point (Kelvin)
592.25
General information
Molecular weight
214.23g/mol
Molar mass
214.2210g/mol
Density
1.4040g/cm3
Appearence

2,4-Dihydroxybenzophenone appears as a yellow crystalline solid. It often takes the form of fine, crystalline powders, which may have a slightly aromatic odor. Its yellow coloration makes it identifiable among benzophenone derivatives, commonly used in various industries.

Comment on solubility

Solubility of (2-hydroxy-4-methoxy-phenyl)-(2-hydroxyphenyl)methanone

The solubility of the compound (2-hydroxy-4-methoxy-phenyl)-(2-hydroxyphenyl)methanone can vary significantly based on multiple factors. Understanding its solubility behavior is essential for applications in pharmaceuticals, agrochemicals, and materials science. Here are some important points to consider:

  • Polarity: The presence of hydroxyl groups (-OH) suggests potential for hydrogen bonding, making the compound more polar, which can enhance its solubility in polar solvents such as water.
  • Functional Groups: Methoxy groups (-OCH₃) contribute to the overall solubility profile; while they have **hydrophobic characteristics**, they can also offer limited solubility in organic solvents.
  • Temperature Dependence: Solubility typically increases with temperature. This relationship can be critical for processes requiring higher concentrations of the compound in solution.
  • pH Sensitivity: The presence of hydroxyl functional groups suggests that the solubility may change with pH, potentially increasing in more basic or acidic conditions due to ionization.

In summary, while (2-hydroxy-4-methoxy-phenyl)-(2-hydroxyphenyl)methanone displays a certain degree of solubility in polar solvents, the extent can be influenced by factors such as temperature, pH, and the presence of different functional groups. As with many organic compounds, conducting empirical solubility tests will yield the most definitive insights into its behavior in various environments.

Interesting facts

Interesting Facts about (2-hydroxy-4-methoxy-phenyl)-(2-hydroxyphenyl)methanone

This intriguing compound is part of the larger family of ketones which are characterized by the presence of a carbonyl group (C=O) bonded to two hydrocarbon groups. What makes this compound particularly fascinating is its dual hydroxyl (-OH) functional groups, which contribute to its potential biological activity and versatility in various applications:

  • Antioxidant Properties: The presence of multiple hydroxyl groups suggests that this compound may exhibit antioxidant effects. Antioxidants are essential for combating oxidative stress and could play a role in health and wellness.
  • Potential in Drug Design: Compounds like this one are often studied for their potential medicinal properties. The structure can be tuned to enhance interactions with specific biological targets, making it a candidate for drug development.
  • Applications in Material Science: The chemical structure of this compound can be leveraged for the design of materials with specialized properties, such as improved thermal stability or enhanced electrical conductivity.
  • Natural Compounds Inspiration: The compound serves as a synthetic analog to curcumin and other natural products known for their health benefits, demonstrating the potential of modifying naturally occurring chemical structures for improved efficacy.

Additionally, the exploration of how such compounds interact with biological systems can lead to a deeper understanding of their mechanisms of action, potentially paving the way for innovative treatments in the fields of pharmacology and toxicology. In the lab, the study of this compound can provide valuable insights into reaction mechanisms, synthesis pathways, and the essence of chemical reactivity.

In summary, (2-hydroxy-4-methoxy-phenyl)-(2-hydroxyphenyl)methanone stands at the intersection of diverse scientific fields, underscoring the importance of chemical research in developing new therapeutic avenues and advancing material technologies.

Synonyms
dioxybenzone
131-53-3
2,2'-DIHYDROXY-4-METHOXYBENZOPHENONE
Benzophenone-8
Dioxybenzon
Advastab 47
Spectra-sorb UV 24
Cyasorb UV 24
(2-Hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)methanone
Methanone, (2-hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)-
Dioxibenzona
Cyasorb UV 24 Light Absorber
UV 24
UF 2
Dioxybenzonum
NSC-56769
(2-hydroxy-4-methoxyphenyl)-(2-hydroxyphenyl)methanone
DTXSID3022403
Benzophenone, 2,2'-dihydroxy-4-methoxy-
B762XZ551X
Benzophenone-8;UV-24
NSC56769
DIOXYBENZONE [MI]
DIOXYBENZONE [INN]
2-(2-hydroxybenzoyl)-5-methoxyphenol
DIOXYBENZONE [USAN]
DIOXYBENZONE [VANDF]
DIOXYBENZONE [MART.]
DIOXYBENZONE [USP-RS]
DIOXYBENZONE [WHO-DD]
(2-hydroxy-4-methoxy-phenyl)-(2-hydroxyphenyl)methanone
DTXCID202403
CHEBI:34208
DIOXYBENZONE [USP MONOGRAPH]
2,2'-dihydroxy-4-methoxy benzophenone
NCGC00016393-01
Dioxibenzonum
CAS-131-53-3
2,2 inverted exclamation marka-Dihydroxy-4-methoxybenzophenone
DIOXYBENZONE (MART.)
DIOXYBENZONE (USP-RS)
DIOXYBENZONE (USP MONOGRAPH)
Dioxybenzonum [INN-Latin]
Dioxibenzona [INN-Spanish]
CCRIS 6231
SR-05000001610
EINECS 205-026-8
NSC 56769
BRN 2055461
UNII-B762XZ551X
AI3-25363
Dioxybenzone [USAN:USP:INN]
MFCD00002218
Spectro-sorb UV 24
BENZOPHENONE 8
Spectra-Sorb UV-24
Spectrum_000978
Dioxybenzone (Standard)
Prestwick0_000898
Prestwick1_000898
Prestwick2_000898
Prestwick3_000898
Spectrum2_001032
Spectrum3_000399
Spectrum4_000519
Spectrum5_000913
Dioxybenzone (USP/INN)
SCHEMBL15894
BSPBio_000716
BSPBio_002217
KBioGR_001097
KBioSS_001458
MLS002154056
BIDD:ER0352
SPECTRUM1500255
SPBio_001243
SPBio_002925
BENZOPHENONE-8 [INCI]
BPBio1_000788
CHEMBL1326877
Dioxybenzone, analytical standard
HSDB 8474
HY-B0966R
KBio2_001458
KBio2_004026
KBio2_006594
KBio3_001437
component of Solaquin (Salt/Mix)
HMS1570D18
HMS1920I04
HMS2091O12
HMS2097D18
HMS2235J06
HMS3371G16
HMS3714D18
Pharmakon1600-01500255
2,2'-dihydroxy-methoxybenzophenone
HY-B0966
Tox21_110417
Tox21_200993
CCG-40196
NSC756742
s4607
AKOS015856203
Benzophenone,2'-dihydroxy-4-methoxy-
Tox21_110417_1
2,2'-dihydroxy-4-methoxy-benzophenone
2,2'-dihydroxy-4-methoxybenzo-phenone
2,2\'-Dihydroxy-4-methoxybenzophenone
CS-4451
DB11221
FD62643
KS-5318
NSC-756742
NCGC00016393-02
NCGC00016393-03
NCGC00016393-04
NCGC00016393-07
NCGC00094657-01
NCGC00094657-02
NCGC00258546-01
2,2a(2)-Dihydroxy-4-methoxybenzophenone
DA-52573
SMR001233373
SBI-0051353.P003
2,2'-Dihydroxy-4-methoxybenzophenone, 98%
AB00051973
D0586
NS00005730
D03853
D89684
AB00051973_08
EN300-7377478
Q2533641
SR-05000001610-1
SR-05000001610-3
BRD-K22193694-001-05-2
BRD-K22193694-001-08-6
BRD-K22193694-001-13-6
S4607 2,2 inverted exclamation marka-Dihydroxy-4-methoxyb
Dioxybenzone, United States Pharmacopeia (USP) Reference Standard
205-026-8