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Umifenovir

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Identification
Molecular formula
C22H25BrClN2O3
CAS number
131707-23-8
IUPAC name
2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one;chloride
State
State

Umifenovir hydrochloride is typically found in a solid state at room temperature. It is usually handled as a powder in pharmaceutical settings, where it is used as an active pharmaceutical ingredient in antiviral medications.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
477.96g/mol
Molar mass
477.9600g/mol
Density
1.3400g/cm3
Appearence

Umifenovir hydrochloride appears as a white or almost white crystalline powder. When observed under different lighting conditions, the crystalline structure can reflect light, giving it a slightly shimmery or glossy appearance. It is often used in its crystalline form in pharmaceutical applications.

Comment on solubility

Solubility of 2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one;chloride

The compound 2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one; chloride exhibits interesting solubility characteristics primarily due to its complex structure. The presence of multiple functional groups significantly influences its interactions with solvents.

Key Factors Affecting Solubility:

  • Ionic Nature: As a chloride salt, the compound is likely to be soluble in polar solvents, especially water, due to the ionic interaction.
  • Hydrophilicity: The hydroxyl group in the structure promotes solubility in water, enhancing its ability to form hydrogen bonds.
  • Chain Length: The piperidine moiety can contribute to varying degrees of hydrophobicity, potentially affecting solubility in organic solvents.

Overall, it can be stated that 2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one; chloride may show a diverse solubility profile, with good solubility in aqueous environments and potentially moderate solubility in organic solvents.
As with many compounds, the solubility may vary widely depending on factors such as temperature, pH, and the presence of other solutes.

Interesting facts

Interesting Facts about 2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one;chloride

The compound 2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one;chloride, often referred to for its complex structure, is a member of the flavonoid family. This category of compounds is well-known for their diverse biological activities and potential therapeutic benefits.

Biological Significance

  • Antioxidant Properties: Compounds like this one often exhibit strong antioxidant activity, meaning they can neutralize harmful free radicals in the body.
  • Potential Therapeutic Uses: Research suggests they may have roles in treating various health issues, including inflammation and cardiovascular diseases.
  • Membrane Activity: The piperidin-1-ium group in its structure enhances its interaction with biological membranes, influencing its biological efficacy.

Structure and Function

The compound's unique structure is composed of a chromen-7-one backbone, modified by hydroxyl and methyl groups, which contribute to its solubility and reactivity. The presence of the piperidinium moiety introduces quaternary ammonium characteristics, impacting its binding affinity to biological targets.

Research and Development

Ongoing research into this compound may unveil:

  • Novel pharmacological uses in drug development
  • Mechanistic insights into its biological functions
  • Strategies for enhancing its efficacy and bioavailability

In summary, 2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one;chloride represents a fascinating intersection of synthetic chemistry and pharmacology, with much potential awaiting exploration. As the field of medicinal chemistry progresses, the exploration of such compounds is invaluable in contributing to our understanding of both their fundamental properties and practical applications.