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Pyrroloquinoline quinone

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Identification
Molecular formula
C21H18N2O5
CAS number
72909-34-3
IUPAC name
2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one;pyridine-2-carboxylate
State
State

At room temperature, pyrroloquinoline quinone is typically a solid. It is often provided as a crystalline powder, which can vary in color from red to light orange. The solid state remains stable under standard conditions.

Melting point (Celsius)
196.50
Melting point (Kelvin)
469.65
Boiling point (Celsius)
633.15
Boiling point (Kelvin)
906.30
General information
Molecular weight
330.31g/mol
Molar mass
330.3060g/mol
Density
1.5490g/cm3
Appearence

Pyrroloquinoline quinone typically appears as red crystalline powder. It is water-soluble and may exhibit different shades depending on the concentration in solution. When placed in a solvent, it may display a range of colors from reddish to pale yellow depending on the solution's nature and concentration.

Comment on solubility

Solubility of 2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one; pyridine-2-carboxylate

The solubility of 2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one; pyridine-2-carboxylate is influenced by several factors, primarily due to its complex structure that involves both aromatic and ionic components. Here are some key considerations:

  • Polar vs. Nonpolar Solvents: As a compound with ionic characteristics from the piperidine component, it is likely to be more soluble in polar solvents such as water. Nonpolar solvents may not effectively dissolve this compound due to the presence of polar functional groups.
  • pH Sensitivity: The solubility can vary significantly with pH. The piperidinium group can exist in both protonated and deprotonated forms depending on the acidity of the solution, which affects solubility.
  • Hydrogen Bonding: The presence of hydroxyl groups allows for potential hydrogen bonding with solvents, enhancing solubility in polar environments.
  • Temperature Effects: Increased temperature can often enhance solubility for many organic compounds, and this compound may follow that trend offering greater solubility at elevated temperatures.

In summary, the solubility of this compound can be anticipated to be higher in aqueous solutions where ionic interactions and hydrogen bonding are more favorable. As with many complex organic compounds, it is highly recommended to conduct empirical solubility tests to confirm theoretical predictions.

Interesting facts

Interesting Facts about 2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one; pyridine-2-carboxylate

This unique compound is a fascinating blend of chemical structures, showcasing the intricate nature of organic chemistry. Here are some intriguing points:

  • Biodiversity & Natural Products: Compounds like this one often find their roots in the study of natural products, as chromenes and their derivatives are prevalent in various plants, contributing to the diversity of natural compounds.
  • Biological Activity: This particular structure has garnered attention for its potential biological activities. The functional groups present, such as the hydroxyl and the piperidin-1-ium moiety, may enhance its interaction with biological targets, making it a subject of interest in pharmaceutical research.
  • Polyfunctional Nature: The compound contains multiple functional groups, allowing for versatile reactivity. This polyfunctionality enables it to undergo various chemical transformations, which can be advantageous in synthetic chemistry.
  • Cationic Features: The presence of the piperidin-1-ium group indicates that this compound is charged, lending it unique solubility and reactivity characteristics, particularly in biological systems where charge plays a critical role in interactions.
  • Research Applications: Researchers have hypothesized that compounds like this could serve as lead compounds in drug discovery, especially in designing inhibitors or modulators of critical biological pathways.

Overall, the chemical and biological richness of 2-hydroxy-4-methyl-8-(piperidin-1-ium-1-ylmethyl)chromen-7-one; pyridine-2-carboxylate highlights the vibrant potential of organic compounds in chemistry, paving new avenues for research and application.