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Coumarin 151

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Identification
Molecular formula
C21H19NO3
CAS number
139861-89-7
IUPAC name
2-hydroxy-4-phenyl-8-(1-piperidylmethyl)chromen-7-one
State
State

At room temperature, this compound is typically found in a solid state due to its relatively high melting point.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.15
Boiling point (Celsius)
485.00
Boiling point (Kelvin)
758.15
General information
Molecular weight
353.41g/mol
Molar mass
353.4080g/mol
Density
1.2000g/cm3
Appearence

This compound often appears as a crystalline powder, exhibiting a light yellow to beige color. It may also be slightly off-white depending on purity and exact formulation.

Comment on solubility

Solubility of 2-hydroxy-4-phenyl-8-(1-piperidylmethyl)chromen-7-one

The solubility of 2-hydroxy-4-phenyl-8-(1-piperidylmethyl)chromen-7-one is a critical property that can influence its application in various chemical and biological contexts. This compound, which contains multiple functional groups, displays unique solubility characteristics that are influenced by several factors:

  • Polarity: The presence of a hydroxyl group typically enhances solubility in polar solvents like water, while the phenyl and piperidyl groups may favor solubility in organic solvents.
  • Solvent Choice: This compound is likely to be more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) compared to aqueous solutions.
  • Temperature: Similar to many organic compounds, solubility can increase with higher temperatures, making heating a useful strategy for dissolving this compound effectively.
  • pH Influence: The ionization of functional groups can be affected by pH, so adjusting the pH of the solution could enhance solubility.

In summary, the solubility of 2-hydroxy-4-phenyl-8-(1-piperidylmethyl)chromen-7-one is multifaceted, and understanding these factors contributes to its successful application in research and industry. To quote, “Understanding solubility is as crucial as knowing the compound itself.” This highlights the importance of solvent system selection in optimizing the behavior of this compound in various settings.

Interesting facts

Interesting Facts about 2-Hydroxy-4-phenyl-8-(1-piperidylmethyl)chromen-7-one

The compound 2-hydroxy-4-phenyl-8-(1-piperidylmethyl)chromen-7-one, often referred to in the scientific community for its remarkable properties and potential applications, belongs to a class of chemicals known as flavonoids. These compounds are widely recognized for their diverse roles in nature and their beneficial effects on human health.

Key Features:

  • Flavonoid Derivative: As a flavonoid, this compound contributes to various biological activities, making it a subject of interest for pharmacological studies.
  • Piperidine Moiety: The presence of a piperidine group in its structure adds to its pharmacological potential, providing a mechanism for interaction with biological targets.
  • Antioxidant Properties: Flavonoids are known for their antioxidant capabilities, which help in neutralizing harmful free radicals in the body.
  • Research Potential: The unique structure of this compound has drawn attention in medicinal chemistry for potential uses in treating various diseases, including neurodegenerative disorders.

This compound exemplifies the intersection of natural product chemistry and synthetic methodology. According to researchers, “The exploration of flavonoids may yield significant insights into developing new therapeutic agents.”
Notably, studies have indicated that flavonoids, including this specific compound, can exhibit anti-inflammatory, anticancer, and neuroprotective effects.

Applications in Research:

  • As a possible neuroprotective agent in the context of oxidative stress-related disorders.
  • In the development of natural products as inspiration for novel pharmaceuticals.
  • For understanding the structure-activity relationship essential for designing improved compounds for therapeutic use.

In summary, the 2-hydroxy-4-phenyl-8-(1-piperidylmethyl)chromen-7-one compound is not just a chemical formula; it represents a rich avenue of research that bridges the gap between chemistry and health, showcasing the profound implications such compounds can have in modern medicine.