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Cetirizine hydrochloride

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Identification
Molecular formula
C21H26ClN3O3
CAS number
83881-52-1
IUPAC name
(2-hydroxy-5-phenyl-phenyl)ammonium;chloride
State
State

At room temperature, cetirizine hydrochloride is in a solid state, typically as a crystalline powder. Its stability as a hygroscopic solid makes it suitable for pharmaceutical applications. It is generally used as an antihistamine in its solid form, often processed into tablets or capsules for oral administration.

Melting point (Celsius)
198.00
Melting point (Kelvin)
471.15
Boiling point (Celsius)
273.00
Boiling point (Kelvin)
546.15
General information
Molecular weight
388.88g/mol
Molar mass
388.8830g/mol
Density
1.0000g/cm3
Appearence

Cetirizine hydrochloride appears as a white or almost white crystalline powder. It is generally odorless or may have a slight smell. The compound is hygroscopic, meaning it can absorb moisture from the air, influencing its stability and handling properties.

Comment on solubility

Solubility of (2-hydroxy-5-phenyl-phenyl)ammonium chloride

The solubility of (2-hydroxy-5-phenyl-phenyl)ammonium chloride can be analyzed from its chemical structure and the interactions that occur with solvents. Here are some key points regarding its solubility:

  • Polar Nature: The presence of the ammonium group enhances its polarity, suggesting a decent level of solubility in polar solvents such as water.
  • Hydrogen Bonding: The hydroxyl group (-OH) is capable of forming hydrogen bonds, which further facilitates solubility in aqueous solutions.
  • Chloride Ion Contribution: The chloride ion can also enhance solubility in water due to its ionic nature, which often leads to dissolution in polar solvents.
  • Temperature Effects: It is important to consider that solubility may increase with temperature, typical of many ionic compounds.

In summary, we can predict that (2-hydroxy-5-phenyl-phenyl)ammonium chloride is likely to be soluble in water, but its solubility may vary under different conditions such as temperature and concentration. Further experimental data would provide a clearer understanding of its solubility characteristics.

Interesting facts

Interesting Facts about (2-hydroxy-5-phenyl-phenyl)ammonium Chloride

(2-hydroxy-5-phenyl-phenyl)ammonium chloride, often referred to in scientific literature as a quaternary ammonium compound, exhibits several intriguing properties that make it a subject of interest in the realm of chemistry. Here are some engaging highlights:

  • Functional Versatility: This compound contains a hydroxyl group which imbues it with unique reactivity and solubility properties, making it a valuable intermediate in organic synthesis.
  • Biological Significance: Compounds of this class are often studied for their biological activity. Some derivatives exhibit antimicrobial properties, suggesting potential applications in pharmaceuticals and disinfectants.
  • Chemical Stability: As a quaternary ammonium salt, it typically demonstrates considerable stability and could serve as an effective reagent in various synthetic pathways.
  • Applications in Material Science: The incorporation of this compound into polymers might enhance their performance, particularly in applications requiring antimicrobial properties or improved surface activity.

Quotes from the Field

Research has shown that, "Quaternary ammonium compounds exhibit properties that not only provide effectiveness in antimicrobial applications but also open doors for new technologies in materials science."

With its distinctive structural features, (2-hydroxy-5-phenyl-phenyl)ammonium chloride remains a compelling topic in ongoing research, paving the way for innovative applications across diverse industries.

Synonyms
3-Amino-4-biphenylol hydrochloride
4L74Z7J1LB
1204-59-7
3-Amino-4-hydroxydiphenyl hydrochloride
4-Hydroxy-3-aminodiphenyl hydrochloride
UNII-4L74Z7J1LB
4-BIPHENYLOL, 3-AMINO-, HYDROCHLORIDE
Phenol, 2-amino-4-phenyl-, hydrochloride
BIPHENYL)-4-OL, 3-AMINO-, HYDROCHLORIDE
3-AMINO-(1,1'-BIPHENYL)-4-OL HYDROCHLORIDE
(1,1'-BIPHENYL)-4-OL, 3-AMINO-, HYDROCHLORIDE (1:1)