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Gentisic acid

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Identification
Molecular formula
C7H6O6S
CAS number
490-79-9
IUPAC name
2-hydroxy-5-sulfo-benzoic acid
State
State

Gentisic acid is a solid at room temperature, typically encountered in its crystalline form.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.00
Boiling point (Celsius)
406.00
Boiling point (Kelvin)
679.00
General information
Molecular weight
216.18g/mol
Molar mass
216.1610g/mol
Density
1.7837g/cm3
Appearence

Gentisic acid typically appears as white to yellowish white crystalline powder or needle-like crystals. It is often available in a fine powdered form for laboratory use.

Comment on solubility

Solubility of 2-hydroxy-5-sulfo-benzoic acid

2-hydroxy-5-sulfo-benzoic acid, often referenced in discussions of solubility due to its unique functional groups, exhibits a series of interesting solubility behaviors in various solvents. The presence of both a hydroxyl group and a sulfonic acid group significantly enhances its solubility characteristics.

Characteristics of Solubility:

  • Water Solubility: This compound is highly soluble in water, attributed to the strong hydrogen bonding potential of the hydroxyl group and the ionic nature of the sulfonic acid group.
  • Alcohol Solubility: Solubility is also observed in alcohols, such as ethanol, where the polar interactions are favorable, although to a lesser degree compared to water.
  • Non-Polar Solvents: Generally, 2-hydroxy-5-sulfo-benzoic acid shows limited solubility in non-polar solvents like hexane due to its polar nature and inability to form strong interactions in such environments.

In summary, the solubility of 2-hydroxy-5-sulfo-benzoic acid can be succinctly described as:

  1. Highly soluble in polar solvents (especially water).
  2. Moderately soluble in alcohols.
  3. Poorly soluble in non-polar solvents.

As a final note, the solubility of this compound is a prime example of how functional groups can influence chemical behavior and interactions with solvents. Understanding these solubility dynamics is vital for applications in pharmaceuticals and materials science.

Interesting facts

Interesting Facts About 2-Hydroxy-5-sulfo-benzoic Acid

2-Hydroxy-5-sulfo-benzoic acid, often referred to as a crucial compound in various chemical applications, presents a fascinating study for chemists and students alike. Here are some noteworthy aspects of this compound:

  • Multi-functional Applications: This compound plays a vital role in dye chemistry, particularly in the synthesis of synthetic dyes and pigments, showcasing its versatility.
  • pH Sensitivity: As a sulfonic acid derivative, it is notable for its ability to function effectively across a range of pH levels, which can significantly impact its reactivity and stability in aqueous solutions.
  • Environmental Relevance: The presence of sulfonic acid groups contributes to its water solubility, making it relevant for studies in environmental chemistry, especially concerning water treatment.
  • Biological Insights: Research indicates that derivatives of 2-hydroxy-5-sulfo-benzoic acid can exhibit bioactive properties, lending a potential interest to biochemists exploring medicinal chemistry and therapeutic applications.
  • Structure-Activity Relationship: The unique structure of 2-hydroxy-5-sulfo-benzoic acid facilitates studies around structure-activity relationships, which are crucial for medicinal chemistry and drug design.

In summary, 2-hydroxy-5-sulfo-benzoic acid stands out due to its diverse applications and importance in both academic research and practical applications. As chemists continue to explore its potential, this compound remains a topic of interest in the intersection of chemical science and environmental sustainability.

Synonyms
2-Hydroxy-5-sulfobenzoic acid
5-Sulfosalicylic acid
SULFOSALICYLIC ACID
97-05-2
5-Sulphosalicylic acid
Salicylsulfonic acid
Benzoic acid, 2-hydroxy-5-sulfo-
Salicylic acid, sulfo-
2-Hydroxybenzoic-5-sulfonic acid
Benzoic acid, 2-hydroxysulfo-
Sulphosalicylic acid
Salicylic acid, 5-sulfo-
3-Carboxy-4-hydroxybenzenesulfonic acid
Kalcolor anodizing acid
Sulfosalicylic acid (VAN)
Salicylsulfonic acid (VAN)
Sulphosalicylic acid (VAN)
NSC 190565
EINECS 202-555-6
L8XED79U3U
BRN 0650741
CP 18121
CHEBI:68555
AI3-18246
AI3-32582
5-Sulfosalicylate
5-sulfo-Salicylic acid
NSC-190565
CHEMBL229241
DTXSID7059145
SULFOSALICYLIC ACID [MI]
4-11-00-00702 (Beilstein Handbook Reference)
SULFOSALICYLIC ACID [WHO-DD]
2-hydroxy-5-sulfo-benzoic acid
WLN: WSQR DQ CVQ
cesium 5-sulfosalicylate
UNII-L8XED79U3U
phlogosam
phlogosol
5sulfosalicylic acid
sulfo salicylic acid
SULFOSALICYLIC
5Sulphosalicylic acid
Salicylic acid, sulfo
5-sulfosalicyclic acid
2-hydroxysulfo-Benzoate
Salicylic acid, 5sulfo
2Hydroxy5sulfobenzoic acid
2-hydroxysulfo-Benzoic acid
Benzoic acid, 2hydroxysulfo
SCHEMBL34766
2-Hydroxy-5-sulfobenzoicacid
2Hydroxybenzoic5sulfonic acid
Benzoic acid, 2hydroxy5sulfo
DTXCID1049015
NSC4741
3-carboxy-4-hydroxybenzenesulfonate
3Carboxy4hydroxybenzenesulfonic acid
HY-B1785
NSC-4741
BBL008587
BDBM50219498
NSC190565
STK301570
AKOS000120294
AC-11271
CS-0013816
NS00014762
S0830
EN300-20563
G76479
Q238569
Z104478882
684-226-0
InChI=1/C7H6O6S/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10/h1-3,8H,(H,9,10)(H,11,12,13