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Salicylic acid

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Identification
Molecular formula
C7H6O3
CAS number
69-72-7
IUPAC name
2-hydroxybenzoate;2-hydroxybenzoic acid
State
State

Salicylic acid is a solid at room temperature.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.00
Boiling point (Celsius)
211.00
Boiling point (Kelvin)
484.00
General information
Molecular weight
138.12g/mol
Molar mass
138.1210g/mol
Density
1.4430g/cm3
Appearence

Salicylic acid appears as colorless to white, needle-like crystals, or a white crystalline powder. It is odorless, or may have a slight phenolic odor.

Comment on solubility

Solubility of 2-hydroxybenzoate (2-hydroxybenzoic acid)

The solubility of 2-hydroxybenzoate (or 2-hydroxybenzoic acid) is quite interesting and can be influenced by various factors such as temperature and the nature of the solvent. Here are some key points regarding its solubility:

  • Solvent Dependence: 2-hydroxybenzoate is generally more soluble in organic solvents than in water.
  • Temperature Factor: As temperature increases, the solubility of this compound in water tends to increase as well.
  • Ionization: The carboxylic acid functional group present in the molecule can undergo ionization in aqueous solutions, leading to a higher solubility in basic environments.
  • Hydrogen Bonding: The presence of hydroxyl (-OH) groups enables hydrogen bonding with water, contributing to its solubility under certain conditions.

In summary, the solubility of 2-hydroxybenzoate in water is limited, but it can dissolve better in polar organic solvents. Its behavior changes significantly with varying pH levels, emphasizing the importance of environmental conditions in determining the solubility of this compound.

Interesting facts

Interesting Facts about 2-Hydroxybenzoate (2-Hydroxybenzoic Acid)

2-Hydroxybenzoate, commonly known as salicylic acid, is a significant organic compound that plays a critical role in various fields, including pharmaceuticals, agriculture, and cosmetics. Here are some captivating insights about this versatile compound:

  • Historical Significance: Salicylic acid derives its name from the Latin word "salix," meaning willow tree, as it was first isolated from willow bark. This historical connection highlights its long-standing use in traditional medicine.
  • Pharmaceutical Applications: It is well-known for its use in the treatment of skin disorders such as acne, psoriasis, and dandruff. Salicylic acid acts as a keratolytic agent, helping to exfoliate the skin and unclog pores.
  • Analgesic Properties: In addition to dermatological uses, 2-hydroxybenzoate is a precursor to acetylsalicylic acid, better known as aspirin, which is widely used for pain relief and anti-inflammatory purposes.
  • Natural Occurrence: Salicylic acid is naturally found in various plants, especially in the bark of willow trees and in many fruits. Its role in plants includes acting as a signaling molecule in response to stress conditions.
  • Research Potential: Ongoing research is exploring the compound's potential in various therapeutic applications, including its use in treating certain cancers and as an anti-inflammatory agent in other diseases.

As a scientist, understanding the versatile applications and natural origins of 2-hydroxybenzoate provides vital clues about its biological significance and potential benefits in medicine. This compound demonstrates how a single substance can impact multiple domains of health and well-being.