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N-Hydroxypipecolic acid

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Identification
Molecular formula
C7H13NO4
CAS number
99010-12-1
IUPAC name
2-(hydroxycarbamoyl)-4-methyl-pentanoic acid
State
State

N-Hydroxypipecolic acid is a solid at room temperature.

Melting point (Celsius)
118.90
Melting point (Kelvin)
392.10
Boiling point (Celsius)
258.70
Boiling point (Kelvin)
531.90
General information
Molecular weight
159.17g/mol
Molar mass
159.1680g/mol
Density
0.9837g/cm3
Appearence

N-Hydroxypipecolic acid typically exists as a crystalline solid. It appears as white or off-white crystals.

Comment on solubility

Solubility of 2-(hydroxycarbamoyl)-4-methyl-pentanoic acid

The solubility of 2-(hydroxycarbamoyl)-4-methyl-pentanoic acid (C7H13NO4) is influenced by its structural features and functional groups. Several key aspects contribute to its solubility characteristics:

  • Hydrophilicity: The presence of the hydroxy and carbamoyl groups enhances solubility in polar solvents, as these groups can form hydrogen bonds with water molecules.
  • Alkyl Chain: The methyl group contributes hydrophobicity, which can reduce overall solubility in highly polar solvents like water.
  • pH Dependency: The acid functionality may provide variable solubility depending on the pH of the solution, as it can exist in protonated or deprotonated forms.

In summary, the solubility of this compound can be described as follows:

  • High solubility in polar solvents, such as water, due to hydrogen bonding potential.
  • Variable solubility in organic solvents, where the balance between hydrophilic and hydrophobic interactions plays a critical role.

Understanding these solubility properties is essential for applications in pharmaceuticals, where the compound's effectiveness can be highly dependent on its solubility profile.

Interesting facts

Interesting Facts about 2-(hydroxycarbamoyl)-4-methyl-pentanoic acid

The compound 2-(hydroxycarbamoyl)-4-methyl-pentanoic acid is a fascinating example of a multifunctional organic molecule. Here are some engaging insights into its properties and significance:

  • Biological Relevance: This compound possesses characteristics that may suggest a role in biological systems, potentially functioning as an important metabolite.
  • Synthetic Utility: It may serve as a precursor in organic synthesis for creating more complex molecules, making it useful in pharmaceutical chemistry.
  • Hydroxyl Group: The presence of the hydroxy group not only contributes to its solubility in polar environments but also enhances its ability to participate in hydrogen bonding, which is crucial in biochemical interactions.
  • Carbamoyl Functionality: The carbamoyl functional group adds to the compound's reactivity, allowing it to engage in various substitution and elimination reactions.
  • Chirality: This compound exhibits chirality due to the spatial arrangement of its atoms, indicating that it can exist in multiple isomeric forms, each with potentially different biological activities.

The structural uniqueness of 2-(hydroxycarbamoyl)-4-methyl-pentanoic acid not only highlights the complexity of organic compounds but also emphasizes the intricate connections between chemical structure, functional groups, and biological activity. As stated by renowned chemist Linus Pauling, “The best way to have a good idea is to have a lot of ideas.” Understanding such compounds can lead to innovative advancements in material sciences and medicinal chemistry.

In summary, 2-(hydroxycarbamoyl)-4-methyl-pentanoic acid embodies the beauty and complexity of organic chemistry, demonstrating that even a simple-looking molecule can harbor a wealth of scientific intrigue and potential.

Synonyms
SCHEMBL1458463
CINIOMOBGSHXRK-UHFFFAOYSA-N
2-Hydroxycarbamoyl-4-methylpentanoic acid
PD042887