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Salicylate of ethylene glycol

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Identification
Molecular formula
C9H10O4
CAS number
1716-12-7
IUPAC name
2-hydroxyethyl 2-hydroxybenzoate
State
State

At room temperature, 2-Hydroxyethyl 2-hydroxybenzoate is typically in a liquid state. This is due to its relatively low melting point, which means it remains liquid except in colder conditions.

Melting point (Celsius)
-5.00
Melting point (Kelvin)
268.15
Boiling point (Celsius)
226.00
Boiling point (Kelvin)
499.15
General information
Molecular weight
182.18g/mol
Molar mass
182.1750g/mol
Density
1.2700g/cm3
Appearence

2-Hydroxyethyl 2-hydroxybenzoate usually appears as a colorless or pale yellow liquid. It might be a solid at lower temperatures but is generally found in liquid form at room temperature due to its tendency to absorb moisture and dissolve in water.

Comment on solubility

Solubility of 2-Hydroxyethyl 2-Hydroxybenzoate

2-Hydroxyethyl 2-hydroxybenzoate, often known by its common descriptor, exhibits interesting solubility characteristics that are influenced by its chemical structure. The compound features both hydroxyl groups and an ester functional group, contributing to its solubility profile.

Generally, the solubility of 2-Hydroxyethyl 2-hydroxybenzoate can be summarized as follows:

  • Soluble in Water: Due to the presence of hydroxyl groups (–OH), which form hydrogen bonds with water molecules, enhancing solubility.
  • Soluble in Organic Solvents: This compound also dissolves well in various organic solvents such as ethanol, methanol, and acetone, owing to its hydrophobic aromatic ring and intermediate polarity.
  • Temperature Dependency: The solubility tends to increase with temperature, which is a common characteristic of many organic compounds.

It's important to note that while 2-hydroxyethyl 2-hydroxybenzoate is generally soluble, its solubility can be affected by factors like pH and the presence of other ions or solutes in a solution. Therefore, when considering its applications in formulations, one must account for the solvent environment to optimize its usage.

This compound is a great example of how chemical structure can dictate solubility properties, ultimately impacting its behavior and effectiveness in various applications.

Interesting facts

Interesting Facts About 2-Hydroxyethyl 2-Hydroxybenzoate

2-Hydroxyethyl 2-hydroxybenzoate, often referred to as ethyl paraben, is a compound that captures the attention of many in the fields of chemistry and biochemistry. Here are some fascinating insights into this compound:

  • Antimicrobial Properties: This compound is recognized for its ability to inhibit the growth of certain bacteria and fungi, making it an effective preservative in various cosmetics and personal care products.
  • Solvent Properties: Ethyl paraben is used as a solvent in certain chemical reactions, showcasing its versatility beyond mere preservative functions.
  • Pleasing Aroma: It possesses a mild, pleasant odor, which is beneficial in formulations that seek to enhance user experience.
  • Synthetic and Natural Sources: While it can be synthetically produced, it is also found in low concentrations in some fruits, illustrating its occurrence in nature.
  • Controversy in Use: The use of parabens in consumer products has been a topic of debate due to potential health concerns. As a result, some individuals actively seek paraben-free products.

“The study of compounds like 2-hydroxyethyl 2-hydroxybenzoate not only broadens our understanding of chemical behavior but also highlights the need to balance efficacy and safety in product development.”

This compound exemplifies the dynamic relationship between chemistry and real-world applications, making it a significant subject for discussion among scientists and consumers alike. Understanding its properties and implications is essential for harnessing its benefits while addressing safety concerns.

Synonyms
2-Hydroxyethyl salicylate
87-28-5
2-Hydroxyethyl 2-hydroxybenzoate
GLYCOL SALICYLATE
Ethylene glycol monosalicylate
Espirosal
Glycol monosalicylate
Rheumacyl
Spirosal
Glysal
Sarocol
Ethylene glycol salicylate
Monoglycol salicylate
Glykolsalicylat
Phlogont
Traumasenex
Kytta-gel
Ethylene glycol, salicylate
hydroxyethyl salicylate
Benzoic acid, 2-hydroxy-, 2-hydroxyethyl ester
Ethylene glycol, monosalicylate
GL 7
Aethylenglykolsalicylat
1,2-Ethylene glycol monosalicylate
2-Hydroxybenzoic acid 2-hydroxyethyl ester
Salicylic acid, 2-hydroxyethyl ester
3I1VBB7AXH
Ethylenglycol-monosalicylsaeureester
NSC-72097
DTXSID4048987
CHEBI:86541
2-hydroxyethyl 2-oxidanylbenzoate
Ethylene glycol monosali
Glycol salicylate (JAN)
EINECS 201-737-2
MFCD00002862
NSC 72097
.beta.-Hydroxyethyl salicylate
AI3-05033
GLYCOL SALICYLATE [MI]
2-Hydroxybenzoic acid, 2-hydroxyethyl ester
GLYCOL SALICYLATE [JAN]
DTXCID4028913
LVYLCBNXHHHPSB-UHFFFAOYSA-
GLYCOL SALICYLATE [MART.]
GLYCOL SALICYLATE [WHO-DD]
NCGC00159379-03
Salicylic acid, 2-hydroxyethyl ester (8CI)
HYDROXYETHYL SALICYLATE [EP MONOGRAPH]
GLYCOL SALICYLATE (MART.)
HYDROXYETHYL SALICYLATE (EP MONOGRAPH)
UNII-3I1VBB7AXH
Menthoneurin
Norgesic (TN)
Phlogont (TN)
2-hydroxyethyl-salicylate
bmse000750
Glycol salicylate (Standard)
SCHEMBL15402
CHEMBL173562
GLYCOL SALICYLATE [INCI]
HY-B2208R
CS-B1707
HY-B2208
NSC72097
Salicylic Acid 2-Hydroxyethyl Ester
Tox21_113462
ethyleneglycolmonosalicylic acid ester
AKOS009075810
DB11323
CAS-87-28-5
NCGC00159379-02
NCGC00159379-04
DA-69794
FE170932
SY032913
E0113
NS00013719
EN300-22340
D01557
E78954
SBI-0654048.0001
Ethylene glycol monosalicylate, >=98.0% (GC)
Q117422
SR-01000944719
SR-01000944719-1
BRD-K41866823-001-01-3
Hydroxyethyl salicylate, European Pharmacopoeia (EP) Reference Standard
201-737-2