Skip to main content

Ioxitalamic acid

ADVERTISEMENT
Identification
Molecular formula
C12H16I3N3O6
CAS number
50838-59-8
IUPAC name
2-hydroxyethyl 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodo-benzoate
State
State

At room temperature, ioxitalamic acid is typically in a solid state.

Melting point (Celsius)
218.00
Melting point (Kelvin)
491.15
Boiling point (Celsius)
403.10
Boiling point (Kelvin)
676.25
General information
Molecular weight
821.05g/mol
Molar mass
821.0490g/mol
Density
2.3200g/cm3
Appearence

Ioxitalamic acid is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-hydroxyethyl 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodo-benzoate

The solubility of 2-hydroxyethyl 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodo-benzoate can be intriguing due to its complex structure. This compound features various functional groups that influence its solubility characteristics:

  • Hydrophilicity vs. Hydrophobicity: The presence of the hydroxyethyl and acetamido groups contributes to a more hydrophilic nature, which could enhance solubility in polar solvents like water.
  • Iodine Atoms: The three iodine substitutions might increase the molecule's overall hydrophobic character, potentially lowering its solubility in aqueous conditions.
  • Solvent Compatibility: This compound may exhibit better solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) due to less polar interactions.

To summarize, although the hydrophilic groups suggest that this compound could dissolve in water to some extent, the presence of multiple iodinated substituents may create a balance that hinders complete solubility. Therefore, it is essential to consider the context, such as solvent conditions and temperature, when predicting solubility behavior.

Interesting facts

Interesting Facts about 2-hydroxyethyl 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodo-benzoate

This compound, known for its complex structure, has gained traction in various fields including pharmaceuticals and imaging. Its unique arrangement of iodine atoms contributes to its functionality, making it a valuable asset in medical applications.

Key Features:

  • Iodine Attributes: The tri-iodo substitution significantly enhances its radiopacity, making it an important component in contrast agents for medical imaging.
  • Pharmaceutical Relevance: Due to the presence of acetamido groups, the compound can serve as a prodrug, facilitating the delivery of therapeutic agents.
  • Hydroxyl Functionality: The hydroxyethyl moiety not only increases solubility but also provides sites for further chemical modification and functionalization.

Furthermore, researchers have noted that compounds with such iodine substitutions can exhibit interesting biological activities, which are under investigation for potential therapeutic uses. According to a recent study, "the manipulation of iodine levels within molecule structures can lead to enhanced biological efficacy against certain pathogens."
This highlights the significance of chemical structure in the functionality of compounds.

The synthesis and characterization of 2-hydroxyethyl 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodo-benzoate continue to be a fascinating topic, as scientists explore the limits of its applications and its interaction with biological systems. With ongoing research, the potential of this compound may unveil even more innovative applications in medicine and beyond.

Synonyms
B 6500
BRN 2784216
BENZOIC ACID, 3-ACETAMIDO-5-ACETAMIDOMETHYL-2,4,6-TRIIODO-, 2-HYDROXYETHYL ESTER
1555-88-0
DTXSID20165908
3-Acetamido-5-acetamidomethyl-2,4,6-triiodobenzoic acid 2-hydroxyethyl ester
DTXCID4088399