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2-Hydroxyethyl carbamate

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Identification
Molecular formula
C3H7NO3
CAS number
627-12-3
IUPAC name
2-hydroxyethyl carbamate
State
State

At room temperature, 2-hydroxyethyl carbamate is typically in a solid state, appearing as crystalline powder.

Melting point (Celsius)
45.50
Melting point (Kelvin)
318.65
Boiling point (Celsius)
298.00
Boiling point (Kelvin)
571.15
General information
Molecular weight
105.11g/mol
Molar mass
105.1100g/mol
Density
1.2603g/cm3
Appearence

2-Hydroxyethyl carbamate appears as a white to off-white crystalline solid. It may also be encountered in a powder form.

Comment on solubility

Solubility of 2-hydroxyethyl carbamate

2-hydroxyethyl carbamate, with the chemical formula C3H9NO3, exhibits interesting solubility characteristics that are pivotal in its various applications. Understanding solubility can provide insights into its behavior in different solvents, which is essential for practical uses.

Key Points About Solubility

  • Solvent Compatibility: 2-hydroxyethyl carbamate is generally soluble in polar solvents such as water and alcohols due to its hydroxyl groups that can form hydrogen bonds.
  • Temperature Influence: Increased temperature can enhance the solubility of 2-hydroxyethyl carbamate in aqueous solutions, following the common trend that solubility often increases with temperature.
  • pH Dependence: The solubility may also vary with pH, particularly since it contains functional groups that can gain or lose protons in different environments.

Overall, solubility plays a vital role in the functionality and applicability of 2-hydroxyethyl carbamate, making it behavior in solvent systems particularly noteworthy. This compound's ability to dissolve effectively in polar environments underscores its utility in various chemical processes and formulations:

"The solubility of a compound is not just a property, but a gateway to its potential."
Interesting facts

Interesting Facts About 2-Hydroxyethyl Carbamate

2-Hydroxyethyl carbamate is a fascinating compound that has gained attention in various therapeutic and industrial applications. Here are some notable aspects:

  • Biological Relevance: This compound serves as a significant intermediate in the synthesis of pharmaceuticals and agrochemicals, highlighting its important role in drug development.
  • Polymer Chemistry: 2-Hydroxyethyl carbamate is also a precursor for a range of polyurethanes. Its ability to modify polymer properties makes it valuable in materials science.
  • Research Applications: Scientists are exploring its potential in the field of bioconjugation, where it can be used to attach biomolecules in a controlled manner, aiding in the development of targeted therapies.
  • Environmental Considerations: Understanding the degradation pathways and toxicity of carbamate derivatives, including 2-hydroxyethyl carbamate, is essential for assessing environmental impacts, particularly since many carbamates can affect biological systems.
  • Historical Context: Since the early 20th century, carbamate compounds have been studied for their insecticidal properties, contributing to advancements in agricultural chemistry.

In summary, 2-hydroxyethyl carbamate is not merely a chemical entity; it is a versatile compound with a broad spectrum of applications in science and industry. Its role as a building block in drug synthesis and polymer production emphasizes its importance in ongoing research and commercial endeavors.

Synonyms
2-Hydroxyethyl carbamate
HYDROXYETHYL CARBAMATE
2-Hydroxyethylcarbamate
1,2-Ethanediol, 1-carbamate
beta-Hydroxyethylcarbamate
Ethylene glycol monocarbamate
CCRIS 6845
HSDB 2611
NSC 3139
NSC-3139
EINECS 226-405-4
UNII-MXE9F638CE
BRN 1746943
DTXSID10883487
HYDROXYETHYL CARBAMATE [HSDB]
2-hydroxy-EC
2-HEC
2Hydroxyethylcarbamate
2Hydroxyethyl carbamate
betaHydroxyethylcarbamate
betaHydroxyethyl carbamate
1,2Ethanediol, monocarbamate
Carbamic acid, 2hydroxyethyl ester
DTXCID001023015
226-405-4
4-03-00-00069 (beilstein handbook reference)
5395-01-7
Ethylene glycol, monocarbamate
Carbamic acid, 2-hydroxyethyl ester
1,2-Ethanediol, monocarbamate
MXE9F638CE
.beta.-Hydroxyethyl carbamate
beta-Hydroxyethyl carbamate
1, monocarbamate
MFCD01738425
WLN: ZVO2Q
SCHEMBL438344
NSC3139
AKOS006277954
SB84412
AS-58082
DB-211703
CS-0218046
NS00044665
EN300-99017
A11395
Q27284286
Z1198158440