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Methylene Blue

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Identification
Molecular formula
C16H18ClN3S
CAS number
61-73-4
IUPAC name
2-hydroxyethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium;chloride
State
State
At room temperature, methylene blue is a solid. It is commonly used in its hydrated form, known for being a blue powder or crystalline solid.
Melting point (Celsius)
100.00
Melting point (Kelvin)
373.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
319.85g/mol
Molar mass
319.8510g/mol
Density
1.0200g/cm3
Appearence

Methylene Blue typically appears as a dark green solid that gives a deep blue solution when dissolved in water. It is known for its bright blue coloration and is sensitive to light exposure.

Comment on solubility

Solubility of 2-hydroxyethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium;chloride

The solubility of 2-hydroxyethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium;chloride can be quite intriguing, especially when considering its unique chemical structure. Several factors influence its solubility, including:

  • Polarity: The presence of hydroxyl groups tends to enhance solubility in polar solvents, such as water.
  • Ionization: As a chloride salt, it will dissociate in solution, potentially increasing solubility.
  • Hydrophobic Regions: The phenothiazine moiety presents hydrophobic characteristics which may limit solubility in purely aqueous solutions.

Overall, the solubility could be categorized as moderately soluble in water, but less so in nonpolar solvents. This compound likely demonstrates a balancing act between its polar and nonpolar characteristics, making it essential for experimentation under specific conditions to determine the exact solubility profile. As with many organic salts, one might observe:

  1. Enhanced solubility at higher temperatures.
  2. Decreased solubility in highly acidic or basic environments.

In summary, while solubility is influenced by multiple factors, careful consideration should be given to the solvent choice and environmental conditions when analyzing this compound's behavior in solution.

Interesting facts

Interesting Facts About 2-Hydroxyethyl-Dimethyl-(1-Methyl-2-Phenothiazin-10-Yl-Ethyl)Ammonium Chloride

2-Hydroxyethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium chloride, often referred to as a quaternary ammonium compound, is a fascinating chemical with various applications in the fields of chemistry and pharmacology. Here are some notable aspects:

  • Quaternary Ammonium Compounds: This compound belongs to a class of compounds recognized for their ability to act as surfactants. They are often used in industry for their antimicrobial properties.
  • Biological Significance: The phenothiazine moiety provides unique pharmacological properties. Compounds like this have been studied extensively for their potential use as antipsychotic medications, as they tend to have a calming effect on the nervous system.
  • Electrolyte Properties: As a salt, it can dissociate in a solution, making it interesting in studies involving ionic conductivity. Understanding its behavior can aid in the development of various chemical processes.
  • Industrial Applications: Beyond its medicinal uses, 2-hydroxyethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium chloride is utilized in formulations for disinfectants, hair conditioners, and as a fabric softener.
  • Synthesis Methods: The synthesis of this compound often involves multi-step reactions that highlight its complexity, making it an interesting subject for organic chemistry experiments and teachings.
  • Research Focus: Ongoing research continues to examine its interactions with biological systems, exploring how it can be optimized for therapeutic uses, particularly in the treatment of psychiatric disorders.

In summary, 2-hydroxyethyl-dimethyl-(1-methyl-2-phenothiazin-10-yl-ethyl)ammonium chloride is not just a chemical compound, but a bridge connecting various fields of science—from medicine to industrial applications. Its multifaceted nature shows how a single compound can play many roles in advancing both chemical research and practical application.

Synonyms
2090-54-2
promethazine hydroxyethyl chloride
N-Hydroxyethylpromethazine chloride
O3842T8RNK
2-hydroxyethyl-dimethyl-(1-phenothiazin-10-ylpropan-2-yl)azanium;chloride
Lergobit
(2-Hydroxyethyl)dimethyl(1-methyl-2-phenothiazin-10-ylethyl)ammonium chloride
Ammonium, (2-hydroxyethyl)dimethyl(1-methyl-2-phenothiazin-10-ylethyl)-, chloride
Aprobit R
EINECS 218-238-0
UNII-O3842T8RNK
SCHEMBL1042770
DTXSID70875166
(2-Hydroxyethyl)dimethyl(alpha-methyl-10H-phenothiazine-10-ethyl) chloride
1-(10-Phenothiazinylmethyl)ethyl-2-hydroxyethyldimethylammonium chloride
10H-Phenothiazine-10-ethanaminium, N-(2-hydroxyethyl)-N,N,alpha-trimethyl-, chloride
NS00124309
N-HYDROXYETHYLPROMETHAZINE CHLORIDE [MI]
PROMETHAZINE HYDROXYETHYL CHLORIDE [WHO-DD]
Q27285267
10H-PHENOTHIAZINE-10-ETHANAMINIUM, N-(2-HYDROXYETHYL)-N,N,.ALPHA.-TRIMETHYL-, CHLORIDE
10H-PHENOTHIAZINE-10-ETHANAMINIUM, N-(2-HYDROXYETHYL)-N,N,.ALPHA.-TRIMETHYL-, CHLORIDE (1:1)
Aprobit; 10H-Phenothiazine-10-ethanaminium, N-(2-hydroxyethyl)-N,N,a-trimethyl-, chloride (1:1); (2-Hydroxyethyl)dimethyl(1-methyl-2-phenothiazin-10-ylethyl)ammonium chloride (7CI); 10H-Phenothiazine-10-ethanaminium, N-(2-hydroxyethyl)-N,N,a-trimethyl-, chloride (