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Benzyl 2-hydroxyethylcarbamate

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Identification
Molecular formula
C10H13NO3
CAS number
3775-23-7
IUPAC name
2-hydroxyethyl N-benzylcarbamate
State
State

The compound is generally found in a solid state at room temperature.

Melting point (Celsius)
64.00
Melting point (Kelvin)
337.15
Boiling point (Celsius)
298.30
Boiling point (Kelvin)
571.45
General information
Molecular weight
195.22g/mol
Molar mass
195.2200g/mol
Density
1.2250g/cm3
Appearence

Benzyl 2-hydroxyethylcarbamate typically appears as a white to off-white crystalline solid. It may form clear, often needle-like crystals.

Comment on solubility

Solubility of 2-hydroxyethyl N-benzylcarbamate

The solubility of 2-hydroxyethyl N-benzylcarbamate can vary depending on several factors, including solvents and temperature. This compound tends to exhibit moderate solubility in various organic solvents due to its structural characteristics. Here are some key points regarding its solubility:

  • Water Solubility: Generally, 2-hydroxyethyl N-benzylcarbamate is sparingly soluble in water, influenced by its alkyl and aromatic groups, which create hydrophobic interactions.
  • Organic Solvents: It shows better solubility in polar organic solvents such as methanol, ethanol, and acetone, which can effectively disrupt its intermolecular forces.
  • Temperature Effect: Increased temperatures often lead to enhanced solubility, allowing for more efficient dissolution of the compound in various solvents.
  • pH Influence: The solubility may also change with pH, as the ionization of functional groups can affect overall solubility in aqueous conditions.

As a result, for practical applications, it is critical to consider the choice of solvent and the conditions under which this compound will be used. Understanding these solubility traits will aid in optimizing reactions and formulations that involve 2-hydroxyethyl N-benzylcarbamate.

Interesting facts

Interesting Facts About 2-Hydroxyethyl N-benzylcarbamate

2-Hydroxyethyl N-benzylcarbamate is a fascinating compound that plays a significant role in various fields, particularly in medicinal chemistry and materials science. Here are some interesting aspects of this compound:

  • Versatile Applications: This compound is often used as an intermediate in the synthesis of pharmaceutical products. Its unique structure allows it to serve as a key block for many bioactive molecules.
  • Inhibitory Properties: Research has shown that 2-hydroxyethyl N-benzylcarbamate can exhibit inhibitory effects against certain enzymes, making it a candidate for the development of drug therapies, particularly in the area of cancer treatment.
  • Adhesives and Coatings: The carbamate group in the molecule is known for its usefulness in creating polymers. When modified, this compound can enhance the adhesive properties of materials, providing stronger bonds in various applications.
  • Biocompatibility: As interest grows in the development of biodegradable and biocompatible materials, compounds like 2-hydroxyethyl N-benzylcarbamate are increasingly being studied for their potential use in medical devices and drug delivery systems.
  • Structural Diversity: The ability to modify the benzyl group in this compound allows for the design of a diverse array of derivatives, which can be tailored for specific biological activities or physical properties.

In summary, 2-hydroxyethyl N-benzylcarbamate is a compound with a wealth of potential applications, particularly in the pharmaceutical industry and materials science. Its diverse properties and the possibility for structural modifications make it a compound of remarkable interest for ongoing research and development.

Synonyms
Buramate
4663-83-6
Hyamate
2-Hydroxyethyl N-benzylcarbamate
Buramat
2-Hydroxyethyl benzylcarbamate
AC 601
Buramato
AC-601
Carbamic acid, (phenylmethyl)-, 2-hydroxyethyl ester
Ethylene glycol, mono(benzylcarbamate)
NSC-30223
NSC-30781
Q9HDA6U6V4
CARBAMIC ACID, BENZYL-, 2-HYDROXYETHYL ESTER
Buramate-d7
Buramate (USAN)
NSC30223
BURAMATE [USAN]
Buramatum
Buramate [USAN:INN]
Buramatum [INN-Latin]
Buramato [INN-Spanish]
Benzylurethane du glycol [French]
Benzylurethane du glycol
242 HC
NSC 30223
UNII-Q9HDA6U6V4
Benzylcarbamic acid 2-hydroxyethyl ester
BRN 2838813
BURAMATE [INN]
BURAMATE [MI]
SCHEMBL79198
4-12-00-02251 (Beilstein Handbook Reference)
CHEMBL2103933
DTXSID70196888
CHEBI:134851
EAA66383
NSC30781
AKOS006272292
CCG-213427
TS-09840
HY-116826
NS00126895
D02639
EN300-203841
G55026
AB01563075_01
SR-01000944202
SR-01000944202-1
BRD-K30360804-001-01-3
Q27287146
Z1198155419