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2-Hydroxyethyl nicotinate

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Identification
Molecular formula
C8H9NO3
CAS number
65138-19-4
IUPAC name
2-hydroxyethyl pyridine-3-carboxylate
State
State

At room temperature, 2-hydroxyethyl nicotinate is in a solid state, presenting as a crystalline powder.

Melting point (Celsius)
67.00
Melting point (Kelvin)
340.15
Boiling point (Celsius)
319.10
Boiling point (Kelvin)
592.25
General information
Molecular weight
181.18g/mol
Molar mass
181.1840g/mol
Density
1.1560g/cm3
Appearence

2-Hydroxyethyl nicotinate typically appears as a white crystalline solid at room temperature.

Comment on solubility

Solubility of 2-hydroxyethyl pyridine-3-carboxylate

The solubility of 2-hydroxyethyl pyridine-3-carboxylate is a key factor that influences its applications in various chemical processes. This compound typically exhibits moderate solubility in polar solvents, especially in water, due to the presence of polar functional groups.

Here are some notable aspects regarding its solubility:

  • Polar Solvents: The hydroxyl group (-OH) enhances its interaction with water molecules, making it more soluble.
  • Organic Solvents: It may also dissolve well in other polar organic solvents such as ethanol and methanol, although solubility can significantly vary.
  • pH Influence: The solubility can be affected by pH changes, particularly due to the carboxylic acid group which can ionize in different pH environments.
  • Temperature Dependence: As with many chemical compounds, increasing temperature generally increases solubility in most solvents.

In summary, while 2-hydroxyethyl pyridine-3-carboxylate is soluble in water and polar solvents, its solubility can be influenced by several factors, including pH, temperature, and the nature of the solvent. Understanding these properties is crucial for its effective use in laboratory and industrial applications.

Interesting facts

Interesting Facts about 2-Hydroxyethyl Pyridine-3-Carboxylate

2-Hydroxyethyl pyridine-3-carboxylate, often abbreviated as HEPC, is a lesser-known chemical compound that has drawn the attention of researchers due to its unique structural features and potential applications in various fields. Here are some intriguing aspects of this compound:

  • Structural Significance: The compound possesses a pyridine ring, which is a six-membered aromatic ring containing nitrogen. This feature contributes to its stability and reactivity, making it an interesting candidate for various chemical reactions.
  • Functional Groups: The presence of both hydroxyethyl and carboxylate groups in its structure allows HEPC to exhibit amphipathic properties. This characteristic makes it suitable for use in biological systems and as a reaction medium.
  • Potential Applications: HEPC has potential applications in pharmaceuticals. Compounds with pyridine structures are often found in drug molecules due to their ability to interact with biological receptors effectively.
  • Research Interest: Scientists are investigating the compound for its possible role as a catalyst in organic synthesis. The combination of its hydroxy and carboxylate functionalities can facilitate various reactions, which is a focus of ongoing studies.
  • Biological Insight: As researchers explore its pharmacological properties, HEPC is being studied for its potential effects on metabolic pathways and enzyme activity, making it a valuable compound in biochemistry.

In summary, 2-hydroxyethyl pyridine-3-carboxylate is a compound that epitomizes the intersection of chemistry and potential biological applications. It serves as a reminder of the vast and intricate world hidden within the realm of chemical compounds. As one renowned chemist stated, "The greatest discoveries are often made by looking at the familiar through new eyes."

Synonyms
Etofibrate 2-hydroxymethylnicotinate
2-Hydroxyethyl nicotinate
Ethiacin
BRN 0131597
EOHMN
3-Pyridinecarboxylic acid, 2-hydroxyethyl ester
NICOTINIC ACID, 2-HYDROXYETHYL ESTER
DTXSID50189697
4-22-00-00369 (Beilstein Handbook Reference)
DTXCID10112188
3612-80-4
2-hydroxyethyl pyridine-3-carboxylate
SCHEMBL9717090
AS-82851
E77685