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Choline

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Identification
Molecular formula
C5H14NO
CAS number
62-49-7
IUPAC name
2-hydroxyethyl(trimethyl)ammonium
State
State

Choline is typically found as a viscous liquid at room temperature and is often used in its chloride salt form, which is solid.

Melting point (Celsius)
-61.00
Melting point (Kelvin)
212.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
104.17g/mol
Molar mass
104.1700g/mol
Density
1.0480g/cm3
Appearence

Choline is a colorless, viscous, and highly hygroscopic liquid. It has a faint fishy odor and is often available in solution form.

Comment on solubility

Solubility of 2-hydroxyethyl(trimethyl)ammonium

2-hydroxyethyl(trimethyl)ammonium (C5H14NO) exhibits notable solubility characteristics that are worth exploring. This compound typically shows good solubility in polar solvents, primarily due to the presence of both the hydroxy and quaternary ammonium groups.

Key Points about Solubility:

  • It is highly soluble in water because of the ability to engage in hydrogen bonding.
  • The quaternary ammonium cation enhances solubility in various polar solvents.
  • Generally exhibits limited solubility in non-polar solvents due to its polar functional groups.

In summary, the solubility of 2-hydroxyethyl(trimethyl)ammonium is influenced significantly by its polar nature, making it an important compound in various chemical applications where solubility in water is desired. As noted, "the polarity of a solute often dictates its solubility in a solvent," thus reinforcing its efficient interaction with water and polar media.

Interesting facts

Interesting Facts about 2-Hydroxyethyl(trimethyl)ammonium

2-Hydroxyethyl(trimethyl)ammonium, often referred to as a quaternary ammonium compound, has garnered significant interest in various fields, particularly in biochemistry and materials science. Here are some fascinating facts about this compound:

  • Quaternary Structure: This compound features a quaternary ammonium structure, meaning it has four carbon-containing groups bonded to a nitrogen atom. This unique structure contributes to its properties, making it effective in a variety of applications.
  • Biocompatibility: Due to its positively charged nitrogen and hydroxyl group, 2-hydroxyethyl(trimethyl)ammonium exhibits a favorable interaction with biological systems. It is often explored for use in pharmaceuticals and as a biocompatible surfactant.
  • Versatile Applications: The molecule is utilized not only in the biomedical field but also in industries such as cosmetics, agriculture, and cleaning products. Its surfactant properties allow it to function effectively in emulsifying and solubilizing agents.
  • Antimicrobial Properties: Many quaternary ammonium compounds, including this one, are recognized for their antimicrobial properties. They are often used in disinfectants and antiseptics due to their ability to disrupt microbial cell membranes.
  • Compatibility with Other Compounds: 2-Hydroxyethyl(trimethyl)ammonium can form synergistic relationships with other surfactants and polymers, enhancing their performance in formulations and contributing to improved product efficacy.

In summary, 2-hydroxyethyl(trimethyl)ammonium stands out due to its unique chemical structure and broad range of applications. As researchers continue to explore its properties, this compound has the potential to lead to innovative solutions in various scientific disciplines.

Synonyms
choline
Choline ion
Bilineurine
62-49-7
Choline cation
2-Hydroxy-N,N,N-trimethylethanaminium
Cholinum
Ethanaminium, 2-hydroxy-N,N,N-trimethyl-
(2-Hydroxyethyl)trimethylammonium
trimethylethanolamine
vitamin J
N-trimethylethanolamine
CCRIS 5847
2-hydroxyethyl(trimethyl)azanium
AI3-24208
N,N,N-trimethylethanol-ammonium
CHEBI:15354
BRN 1736748
(beta-hydroxyethyl)trimethylammonium
UNII-N91BDP6H0X
EINECS 200-535-1
N91BDP6H0X
NANOVESON C
CHEMBL920
(2-hydroxyethyl)trimethylazanium
3-04-00-00651 (Beilstein Handbook Reference)
2-HYDROXYETHYL)TRIMETHYLAMMONIUM
2-hydroxy-N,N,N-trimethyl-ethanaminium
Bilineurine; Choline cation; Choline ion; Nanoveson C; Vitamin J
CHT
CARBACHOL IMPURITY A (EP IMPURITY)
CARBACHOL IMPURITY A [EP IMPURITY]
NSC402838
NCGC00015219-03
2-hydroxyethyl(trimethyl)ammonium
1oba
2reg
3ppq
Choline (DCF)
Choline (8CI)
Spectrum_000258
2ha3
3r6u
Ethanaminium,2-hydroxy-N,N,N-trimethyl-
CHOLINE [VANDF]
CHOLINE [MI]
Spectrum2_001938
Spectrum4_000867
Spectrum5_001579
Lopac-C-1754
CHOLINE [WHO-DD]
bmse000285
bmse000953
bmse001003
Epitope ID:116046
SCHEMBL3142
Lopac0_000180
KBioGR_001533
KBioSS_000738
DivK1c_000107
N,N,N-trimethylethanolammonium
SPBio_001975
GTPL4551
DTXSID8043789
2-hydroxyethyl-trimethyl-ammonium
KBio1_000107
KBio2_000738
KBio2_003306
KBio2_005874
NSC6393
NINDS_000107
(2-Hydroxyethyl)trimethyl ammonium
mono-2-hydroxyethyltrimethylammonium
NSC-6393
BBL005532
BDBM50026220
STL137772
AKOS005721137
CCG-204275
DB00122
IDI1_000107
NCGC00015219-01
NCGC00015219-02
NCGC00015219-04
NCGC00015219-07
NCGC00015219-10
NCGC00162082-01
SBI-0050168.P003
2-Hydroxy-N,N,N-trimethylammonium chloride
DB-186977
NS00006125
(.BETA.-HYDROXYETHYL)TRIMETHYLAMMONIUM
C00114
D07690
AB00053822_02
Ethanaminium, 2-hydroxy-N,N,N-trimethyl- (9CI)
Q193166
ACETYLCHOLINE CHLORIDE IMPURITY A [EP IMPURITY]
BRD-K77300776-001-01-7
BRD-K77300776-001-02-5
InChI=1/C5H14NO/c1-6(2,3)4-5-7/h7H,4-5H2,1-3H3/q+
200-535-1