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Choline Chloride

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Identification
Molecular formula
C5H14ClNO
CAS number
67-48-1
IUPAC name
2-hydroxyethyl(trimethyl)ammonium;chloride
State
State

Choline chloride is in a solid state at room temperature. It exists as a crystalline powder that is highly soluble in water and alcohol. Being hygroscopic makes it prone to clumping if left exposed to a humid environment.

Melting point (Celsius)
302.00
Melting point (Kelvin)
575.15
Boiling point (Celsius)
-1.50
Boiling point (Kelvin)
271.65
General information
Molecular weight
139.62g/mol
Molar mass
139.6240g/mol
Density
1.0607g/cm3
Appearence

Choline chloride typically appears as a white crystalline solid. It is hygroscopic, meaning it readily absorbs moisture from the air, which can make it appear slightly damp in humid conditions.

Comment on solubility

Solubility of 2-hydroxyethyl(trimethyl)ammonium chloride

The compound 2-hydroxyethyl(trimethyl)ammonium chloride, with the formula C5H14ClNO, exhibits notable characteristics in terms of solubility due to its ionic nature. As a quaternary ammonium salt, it typically demonstrates good solubility in polar solvents.

Key Aspects of Solubility

  • Water Solubility: Compounds like this one are generally soluble in water, thanks to the presence of the chloride ion and the positively charged ammonium group which facilitates hydration.
  • Influence of Temperature: Solubility may increase with rising temperature, making it easier to dissolve in hot water compared to cold.
  • Solvent Polarity: Aside from water, it may also dissolve in other polar solvents such as methanol and ethanol, but is likely to be insoluble in non-polar solvents like hexane.

To summarize, the solubility of 2-hydroxyethyl(trimethyl)ammonium chloride can be described as highly soluble in polar solvents, particularly water. This solubility behavior underscores the compound’s potential utility in various applications, especially in formulations where aqueous solubility is advantageous.

Interesting facts

Exploring 2-Hydroxyethyl(trimethyl)ammonium Chloride

2-Hydroxyethyl(trimethyl)ammonium chloride is a compound that has garnered interest in various fields, particularly in chemistry and biochemistry. This quaternary ammonium salt is notable for its dual functionality and versatile applications. Here are some captivating aspects of this compound:

  • Quaternary Ammonium Structure: Being a quaternary ammonium compound, it contains a nitrogen atom bonded to four alkyl groups, enhancing its solubility and reactivity in various environments.
  • Surfactant Properties: Its unique structure allows it to function as a surfactant, which means it can significantly reduce surface tension in mixtures, making it valuable in detergents and cleaning products.
  • Biocompatibility: The presence of the hydroxyethyl group not only contributes to its water solubility but also enhances biocompatibility, making it suitable for biomedical applications, like drug delivery systems.
  • Antimicrobial Activity: Compounds similar to 2-hydroxyethyl(trimethyl)ammonium chloride have been studied for their antimicrobial properties, often used in disinfectants and antiseptics.
  • Potential in Agriculture: Research indicates that such compounds could also be effective in agricultural formulations, helping to improve crop protection and nutrient uptake.

As we say in science, “The properties of a compound are defined by the nature of its bonds.” Understanding compounds like 2-hydroxyethyl(trimethyl)ammonium chloride not only deepens our knowledge of chemistry but also opens doors to innovative applications that can benefit various sectors.

In conclusion, the study of this compound exemplifies the intersection of chemistry and practical application, highlighting the importance of quaternary ammonium compounds in our daily lives.

Synonyms
CHOLINE CHLORIDE
67-48-1
Hepacholine
Lipotril
Paresan
2-Hydroxy-N,N,N-trimethylethanaminium chloride
Hormocline
(2-Hydroxyethyl)trimethylammonium chloride
Biocolina
Biocoline
Luridin chloride
Choline hydrochloride
Neocolina
Bilineurin chloride
Cholinium chloride
Choline, chloride
Chloride de choline
Choline chlorhydrate
Cholini chloridum
Cloruro de colina
CHOLINE (CL)
Chlorure de choline
Colina cloruro
Choline chloride [INN]
Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, chloride
Choline (chloride)
2-Hydroxyethyl(trimethyl)azanium;chloride
Trimethyl(2-hydroxyethyl)ammonium chloride
CCRIS 3716
HSDB 984
(beta-Hydroxyethyl)trimethylammonium chloride
EINECS 200-655-4
MFCD00011721
NSC 402838
NSC-402838
2-Hydroxy-N,N,N,-trimethylethanaminium chloride
(2-hydroxyethyl)trimethylazanium chloride
DTXSID4020325
FEMA NO. 4500
UNII-45I14D8O27
AI3-18302
Cloruro de colina [INN-Spanish]
CHEBI:133341
Chlorure de choline [INN-French]
Ammonium, (2-hydroxyethyl)trimethyl-, chloride
45I14D8O27
DTXCID20325
CHEMBL282468
EC 200-655-4
2-Hydroxy-N,N,N-trimethylethanaminium chloride (1:1)
Choline chloride - 99%
(2-H2-Hydroxyethyl)trimethylammonium chloride
CHOLINE CHLORIDE (MART.)
CHOLINE CHLORIDE [MART.]
Cloruro de colina (INN-Spanish)
CHOLINE CHLORIDE (USP-RS)
CHOLINE CHLORIDE [USP-RS]
Chlorure de choline (INN-French)
Colina cloruro [DCIT]
Chloride de choline [French]
Cholini chloridum [INN-Latin]
NSC402838
SR-01000075745
2-hydroxyethyl(trimethyl)azanium chloride
cholinii chloridum
Chloride, Choline
cholinium chloratum
Choline Chloride,(S)
2-hydroxyethyl(trimethyl)ammonium chloride
SCHEMBL14957
CHOLINE CHLORIDE [MI]
SPECTRUM1503428
Choline (chloride) (Standard)
CHOLINE CHLORIDE [FCC]
CHOLINE CHLORIDE [HSDB]
CHOLINE CHLORIDE [VANDF]
HMS500F09
HY-B1337R
CHOLINE CHLORIDE [WHO-DD]
HMS1922E20
HMS2093G05
HMS3652D05
HMS3885F09
Pharmakon1600-01503428
Choline chloride [HOEtN1,1,1]Cl
HY-B1337
Tox21_200492
CCG-39465
NSC758473
s4171
AKOS015903458
Choline chloride - 75% water solution
CS-4855
FC01179
FS-3795
NSC-758473
CAS-67-48-1
WLN: Q2K1&1&1 &Q &G
NCGC00095059-01
NCGC00095059-02
NCGC00258046-01
FC157132
FC179365
DB-055035
NS00076292
SW219165-1
(.beta.-Hydroxyethyl)trimethylammonium chloride
D70213
EN300-102823
AB01568267_01
2-Hydroxy-N,N,N-trimethylethan-1-aminium chloride
A835769
Q2964153
SR-01000075745-3
SR-01000075745-5
1CDEFBD7-7905-4D2C-BEA8-44A54D9787D3
F8889-3032
Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, chloride (1:1)
200-655-4