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Choline citrate

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Identification
Molecular formula
C11H26NO10
CAS number
77-91-8
IUPAC name
2-hydroxyethyl(trimethyl)ammonium;citrate
State
State

At room temperature, choline citrate is in a solid state. It is often encountered as a powder making it convenient for measurement and use in various applications.

Melting point (Celsius)
268.00
Melting point (Kelvin)
541.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
129.18g/mol
Molar mass
129.1800g/mol
Density
1.2300g/cm3
Appearence

Choline citrate appears as a white crystalline powder. It is soluble in water and has a hygroscopic nature, meaning it can absorb moisture from the air. This compound is often used in the medical and food industries due to its role as a source of choline and its involvement in various biochemical processes.

Comment on solubility

Solubility of 2-hydroxyethyl(trimethyl)ammonium Citrate

The solubility of 2-hydroxyethyl(trimethyl)ammonium citrate can be understood by considering several key factors:

  • Polarity: This compound features a quaternary ammonium group that enhances its polarity, making it more likely to interact favorably with polar solvents, particularly water.
  • Hydrogen Bonding: The presence of hydroxyl groups (–OH) in the structure allows for potential hydrogen bonding, improving solubility in aqueous environments.
  • pH Sensitivity: The solubility may also depend on the pH of the solution, as acidic or basic conditions can affect the ionization state of the citrate and the ammonium components.

In general, compounds like 2-hydroxyethyl(trimethyl)ammonium citrate are expected to be:

  1. Soluble in water due to their polar characteristics.
  2. Less soluble in non-polar solvents because of their hydrophilic nature.
  3. More soluble at certain pH levels, demonstrating increased solvation behavior.

Overall, it can be stated that 2-hydroxyethyl(trimethyl)ammonium citrate is likely to exhibit favorable solubility properties in aqueous solutions, which are essential for its applications in various chemical and biological contexts.

Interesting facts

Exploring 2-Hydroxyethyl(trimethyl)ammonium Citrate

2-Hydroxyethyl(trimethyl)ammonium citrate is a fascinating compound that plays an essential role in the world of chemistry and biochemistry. Here are some intriguing facts about this compound:

  • Dual Functionality: This compound acts as both a quaternary ammonium salt and a citrate complex, showcasing its versatility in various biochemical applications.
  • Biocompatibility: Due to its ionic nature, 2-hydroxyethyl(trimethyl)ammonium citrate is often explored in formulations for biocompatible materials. This makes it particularly valuable in medical and pharmaceutical applications.
  • Role in Surfactants: It exhibits surfactant properties, meaning it can help lower the surface tension between two liquids or a liquid and a solid. This makes it useful in formulations such as emulsifiers and detergents.
  • Research Applications: This compound is used in various research studies, particularly in the field of drug delivery systems where its properties can enhance the solubility and stability of bioactive molecules.
  • Environmental Benefits: The use of ammonium-based compounds like this citrate in industrial processes can lead to more environmentally friendly practices by reducing harmful emissions and toxic waste.

As a compound rich in potential, 2-hydroxyethyl(trimethyl)ammonium citrate continues to be an area of interest for scientists aiming to harness its unique properties for innovative applications.

Synonyms
Tricholine citrate
UNII-EH8N140TJ7
EH8N140TJ7
EINECS 208-907-5
Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 2-hydroxy-1,2,3-propanetricarboxylic acid (3:1)
DTXSID5060273
CHOLINE CITRATE [WHO-DD]
TRICHOLINE CITRATE [WHO-DD]
Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (3:1)
Citrate, Choline
DTXCID7041758
208-907-5
choline citrate
546-63-4
Tricholine Citrate(ca. 65% in Water)
2-hydroxyethyl(trimethyl)azanium;2-hydroxypropane-1,2,3-tricarboxylate
Tricholine (citrate)
MFCD00059985
Tricholine Citrate (ca.65%inWater)
AKOS025295454
Choline Citrate - ca. 65% in Water
FC31602
HY-W127728
Tricholine Citrate (ca. 65% in Water)
Tricholine citrate, >=65 wt. % in H2O
DB-257160
CS-0185923
NS00080610
Q27277189
2-hydroxy-N,N,N-trimethylethanaminium2-hydroxypropane-1,2,3-tricarboxylate