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N-Hydroxyphthalimide

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Identification
Molecular formula
C8H5NO3
CAS number
524-38-9
IUPAC name
2-hydroxyisoindoline-1,3-dione
State
State

At room temperature, N-Hydroxyphthalimide is in a solid state.

Melting point (Celsius)
229.00
Melting point (Kelvin)
502.15
Boiling point (Celsius)
318.20
Boiling point (Kelvin)
591.35
General information
Molecular weight
163.14g/mol
Molar mass
163.1350g/mol
Density
1.6400g/cm3
Appearence

N-Hydroxyphthalimide appears as a light yellow to yellow-orange crystalline powder. It has a characteristic odor and exhibits good stability under normal conditions.

Comment on solubility

Solubility of 2-hydroxyisoindoline-1,3-dione

2-hydroxyisoindoline-1,3-dione, often referred to as phthalimide, exhibits interesting solubility characteristics that are essential for its applications in various chemical processes and analyses.

Solubility Profile:

  • Solvent Compatibility: This compound is generally soluble in organic solvents such as dichloromethane, dimethyl sulfoxide (DMSO), and ethanol.
  • Water Solubility: 2-hydroxyisoindoline-1,3-dione has limited solubility in water, which can influence its use in formulations and reactions.
  • Temperature Dependence: Like many organic compounds, its solubility may increase with temperature, suggesting that higher temperatures could facilitate dissolution.

When discussing solubility, it is also important to consider the following factors:

  • Influence of pH: The solubility of this compound can vary with the acidity or alkalinity of the solvent, which may enhance or impede its solubility.
  • Structural Considerations: The presence of functional groups, such as the hydroxyl group, affects hydrogen bonding interactions, making it more favorable for solvation in polar environments.

Overall, understanding the solubility of 2-hydroxyisoindoline-1,3-dione is vital in optimizing its use in synthetic and analytical chemistry, allowing for better formulation practices and enhancing its applications in various fields.

Interesting facts

Interesting Facts about 2-Hydroxyisoindoline-1,3-dione

2-Hydroxyisoindoline-1,3-dione, commonly referred to in chemical circles as *HID*, is a fascinating compound with several intriguing characteristics and applications:

  • Nature of the Compound: This compound belongs to the class of isoindolines, which are bicyclic organic compounds known for their unique structural properties.
  • Biological Significance: HID has been studied for its potential as a bioactive agent. Researchers are investigating its roles in various biological processes, highlighting its potential therapeutic applications.
  • Synthetic Utility: The synthesis of HID often serves as a crucial platform for the construction of more complex organic molecules. Its derivatives are frequently explored in medicinal chemistry.
  • Stability Factors: The presence of the hydroxyl group provides *HID* with unique stability characteristics, which can influence how it behaves under various chemical conditions.
  • Applications in Materials Science: Recent studies suggest that compounds like HID can play significant roles in developing new materials, particularly in electronics and photonics, due to their interesting electronic properties.

Overall, the exploration into 2-hydroxyisoindoline-1,3-dione not only contributes to our understanding of organic chemistry but also opens new avenues for research and industrial applications. As scientists continue to unearth the complexities of HID, its significance in both academic and practical settings grows ever more profound.

Synonyms
N-HYDROXYPHTHALIMIDE
524-38-9
2-hydroxyisoindoline-1,3-dione
2-Hydroxy-1H-isoindole-1,3(2H)-dione
2-Hydroxyphthalimide
1H-Isoindole-1,3(2H)-dione, 2-hydroxy-
Phthalimide, N-hydroxy-
2-hydroxyisoindole-1,3-dione
NSC 770
EINECS 208-358-1
n-hydroxyphthalamide
BRN 0131208
BXI99M81X0
AI3-52074
NSC-770
F 802
DTXSID7060170
N-HYDROXYPHTHALIMIDE [MI]
5-21-11-00100 (Beilstein Handbook Reference)
2Hydroxyphthalimide
Phthalimide, Nhydroxy
DTXCID1041188
2Hydroxy1Hisoindole1,3(2H)dione
1HIsoindole1,3(2H)dione, 2hydroxy
208-358-1
MFCD00005891
2-oxidanylisoindole-1,3-dione
CHEMBL276057
2-hydroxy-isoindole-1,3-dione
2-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione
NHPI
UNII-BXI99M81X0
Phthaloxime
2-Hydroxyisoindolin-1,3-dione
N-Hydroxyphalimide
N-hydoxyphthalimide
N-hydroxyphtalimide
N-hydroxypthalimide
N-hyroxyphthalimide
J66
N-hydroxy-phtalimide
N-hydroxylphthalimide
N-hydroxyphthalirnide
n-hydroxy phthalimide
N-hydroxy-phthalimide
N-(Hydroxy)phthalimide
SCHEMBL1410
N-Hydroxyphthalimide (NOP)
N-Hydroxyphthalimide, 97%
N-(HYDROXY)PHTHALIMDE
WLN: T56 BVNVJ CQ
1H-Isoindole-1, 2-hydroxy-
NSC770
SCHEMBL3182600
2-hydroxy-1,3-isoindolinedione
CFMZSMGAMPBRBE-UHFFFAOYSA-
HMS1667D19
BCP21904
HY-Y0396
BBL009697
BDBM50125808
STL141048
1,2-Benzenedicarboximide, N-hydroxy-
AKOS002387742
AB00534
CS-W008848
FH41541
FS-3185
2-hydroxy-1H-isoindol-1,3(2H)-dione
BP-31016
PD127779
2-hydroxyphthalimide;Phthalimide,N-hydroxy-
2-Hydroxy-1H-isoindole-1,3(2H)-dione #
H0395
NS00042393
EN300-86453
N-Hydroxyphthalimide, purum, >=98.0% (T)
D77696
N-Hydroxyphthalimide, Vetec(TM) reagent grade, 97%
Q26296355
F1565-0110
InChI=1/C8H5NO3/c10-7-5-3-1-2-4-6(5)8(11)9(7)12/h1-4,12H
3229-40-1