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Tris

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Identification
Molecular formula
C4H11NO3
CAS number
77-86-1
IUPAC name
2-(hydroxymethyl)-2-nitro-propane-1,3-diol
State
State

At room temperature, Tris is a solid, presented typically in powdered form. It is soluble in water, making it an excellent choice for buffer solutions.

Melting point (Celsius)
171.00
Melting point (Kelvin)
444.15
Boiling point (Celsius)
276.00
Boiling point (Kelvin)
549.15
General information
Molecular weight
121.14g/mol
Molar mass
121.1360g/mol
Density
1.8270g/cm3
Appearence

Tris is a white crystalline powder. It is often used as a buffer in biological and chemical research due to its stability and inertness.

Comment on solubility

Solubility of 2-(hydroxymethyl)-2-nitro-propane-1,3-diol

The solubility characteristics of 2-(hydroxymethyl)-2-nitro-propane-1,3-diol, a compound often referred to for its diverse applications, can be understood through several key aspects:

  • Polar Nature: Due to the presence of multiple hydroxyl (-OH) groups, this compound exhibits considerable polarity.
  • Hydrogen Bonding: The hydroxymethyl groups facilitate strong hydrogen bonding with water molecules, enhancing its ability to dissolve in polar solvents.
  • Solvent Compatibility: It is notably soluble in water, which can be attributed to its molecular structure, allowing it to interact favorably with the solvent.
  • Limited Solubility in Non-Polar Solvents: Conversely, the solubility in non-polar solvents is significantly limited, as expected for most polar compounds.

In summary, the solubility of 2-(hydroxymethyl)-2-nitro-propane-1,3-diol is markedly enhanced in polar solvents like water, which can be summarized in this simple statement: "The more hydroxyl groups present in a compound, the greater its solubility in water." Understanding these solubility properties is crucial for its applications in various chemical and industrial processes.

Interesting facts

Interesting Facts About 2-(Hydroxymethyl)-2-nitro-propane-1,3-diol

2-(Hydroxymethyl)-2-nitro-propane-1,3-diol is a fascinating compound that has attracted attention in various fields of science due to its unique properties and applications. Recognized primarily for its role as a *biocide* and *preservative*, this compound is particularly valued in the formulation of personal care products, pharmaceuticals, and industrial applications.

Key Applications

  • Preservation: It serves as an effective preservation agent, helping to inhibit the growth of bacteria and fungi in consumer products.
  • Biocide Properties: Leveraged for its antimicrobial activity, it minimizes contamination in aqueous formulations.
  • Synthetic Intermediates: It plays a crucial role in the synthesis of various chemical compounds, enhancing the efficiency of synthetic pathways.

Chemical Structure Insight

The unique structure of 2-(Hydroxymethyl)-2-nitro-propane-1,3-diol contributes to its multifunctional behavior. The presence of both hydroxyl and nitro functional groups allows the molecule to interact with biological systems in diverse ways. Researchers often highlight how:

  • The hydroxymethyl group contributes to hydrophilicity, improving solubility in water-based formulations.
  • The nitro group can enhance the reactivity, making it a valuable building block in organic synthesis.

Safety and Regulatory Aspects

As with many chemical compounds, the safety profile of 2-(Hydroxymethyl)-2-nitro-propane-1,3-diol has been a topic of interest among regulatory bodies. It is essential to utilize this compound within prescribed limits to ensure safety for both consumers and the environment. Researchers and manufacturers must adhere to appropriate regulations to facilitate its safe usage.

In conclusion, 2-(Hydroxymethyl)-2-nitro-propane-1,3-diol stands out not just for its practical applications but also for its intricate chemistry. The scientific community continually explores its potential, and it poses exciting avenues for further studies in biochemistry and material science.

Synonyms
Tris(hydroxymethyl)nitromethane
126-11-4
2-(Hydroxymethyl)-2-nitro-1,3-propanediol
Cimcool wafers
Trimethylolnitromethane
1,3-Propanediol, 2-(hydroxymethyl)-2-nitro-
Nitroisobutylglycerol
Trihydroxymethylnitromethane
Nitrotris(hydroxymethyl)methane
2-(Hydroxymethyl)-2-nitropropanediol
2-Nitro-2-(hydroxymethyl)-1,3-propanediol
2-HYDROXYMETHYL-2-NITRO-1,3-PROPANEDIOL
2-Hydroxymethyl-2-nitropropane-1,3-diol
3E794G4ZRB
DTXSID8027034
NSC-17675
DTXCID207034
Isobutylglycerol, Nitro
RefChem:473469
204-769-5
2-(Hydroxymethyl)-2-nitropropane-1,3-diol
Tris nitro
Isobutylglycerol, nitro-
Methane, trimethylolnitro-
MFCD00007395
1,1,1-Tris(hydroxymethyl)nitromethane
NSC 17675
tris-hydroxymethylnitromethane
WLN: WNX1Q1Q1Q
Nitromethylidynetri(methanol)
Caswell No. 495
1, 2-(hydroxymethyl)-2-nitro-
1,1-Tris(hydroxymethyl)nitromethane
Nitromethylidynetrimethanol
C4H9NO5
CAS-126-11-4
HSDB 6810
EINECS 204-769-5
EPA Pesticide Chemical Code 083902
UNII-3E794G4ZRB
AI3-02259
Nitrotrimethylolmethane
2-(Hydroxymethyl)-2 nitro-1,3-propanediol
2-(Hydroxymethyl)-2-nitro- 1,3-propanediol
2-(hydroxymethyl)-2-nitro-propane-1,3-diol
trishydroxymethylnitromethane
SCHEMBL22312
tris hydroxymethyl nitromethane
tris(hydroxymethyl) nitromethane
CHEMBL1895497
NSC2344
AAA12611
NSC-2344
NSC17675
Tox21_200441
Tox21_300295
AC7921
Tris(hydroxymethyl)nitromethane, 98%
AKOS000278326
S.S.T sump saver tablets (Salt/Mix)
CS-W018127
NCGC00164036-01
NCGC00164036-02
NCGC00164036-03
NCGC00254029-01
NCGC00257995-01
AS-17516
SY062183
DB-041809
TRIS(HYDROXYMETHYL)NITROMETHANE [MI]
H0271
NS00006396
ST51037689
EN300-17934
F791509
1,3-PROPANEDIOL, 2-(HYDROXYMETHYL)-2-NITRO
Q10866600
Z57124105
2-HYDROXYMETHYL-2-NITRO-1,3-PROPANEDIOL [HSDB]
F0001-0384