Zidovudine

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Identification

Molecular formula
C10H13N5O4P
CAS Number
30516-87-1
IUPAC Name
[2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-3-yl] dihydrogen phosphate
Molecular Weight
267.24g/mol
Melting Point
(Celsius)
Boiling Point
(Celsius)
Density
1.5900g/cm3
Synonyms
Thymidine 3'-monophosphoric acid
Interesting facts

Fascinating Insights into [2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-3-yl] dihydrogen phosphate

This unique compound is a member of the class of dihydrogen phosphates, a functional group that possesses intriguing properties and applications in various fields, especially in biochemistry and medicinal chemistry.

Key Features

  • Bioactivity: The presence of the pyrimidine ring in the structure is often associated with a variety of biological activities, making it a potential candidate for further pharmaceutical studies.
  • Phosphate Group: The dihydrogen phosphate moiety is known for its role in energy transfer processes within biological systems, particularly in ATP metabolism.
  • Structural Complexity: The four-membered ring of tetrahydrofuran contributes to the compound's three-dimensional structure, impacting its reactivity and interaction with biological targets.

Potential Applications

The compound's design suggests applications in:

  • Drug development, particularly targeting pathways involved in cancer or metabolic diseases.
  • Biochemical studies, where it can serve as a probe for enzyme activity related to nucleotide metabolism.
  • Research into nucleic acid chemistry, due to its structural similarities to nucleotides.

Concluding Thoughts

As a chemist, exploring compounds like this one opens doors to understanding complex biochemical processes and developing novel therapeutic agents. The intricate design of [2-(hydroxymethyl)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-3-yl] dihydrogen phosphate symbolizes the elegance of molecular architecture in nature.

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