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Dacarbazine

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Identification
Molecular formula
C11H13N6O
CAS number
4342-03-4
IUPAC name
2-(hydroxymethyl)-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-3,4-diol
State
State

At room temperature, dacarbazine is typically found in its solid crystalline form.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.15
Boiling point (Celsius)
905.00
Boiling point (Kelvin)
1 178.15
General information
Molecular weight
182.18g/mol
Molar mass
182.1790g/mol
Density
2.0000g/cm3
Appearence

Dacarbazine appears as a white to pale yellow crystalline solid. It may appear as a powder when used in its pharmaceutical form.

Comment on solubility

Solubility of 2-(hydroxymethyl)-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-3,4-diol

The solubility of the compound 2-(hydroxymethyl)-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-3,4-diol (C11H13N6O) can be influenced by various factors due to its complex structure. This compound's solubility can often be characterized as follows:

  • Polarity: The presence of hydroxyl groups and nitrogen atoms in the purine ring suggests that the compound may have a significant polarity, which typically enhances its solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the hydroxymethyl and diol functional groups would further contribute to better solubility in aqueous environments.
  • Solvent Compatibility: The solubility in organic solvents may vary, potentially showing moderate solubility in solvents such as ethanol or DMSO, which can accommodate both polar and non-polar characteristics.

Furthermore, it's essential to note that temperature and pH can play critical roles in the solubility of this compound, as with many biomolecules. Increased temperature generally enhances solubility, while variations in pH can affect the ionization of functional groups, impacting aqueous solubility.

In summary, while 2-(hydroxymethyl)-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-3,4-diol shows promise for good solubility in polar solvents, a detailed solubility profile can vary significantly based on environmental conditions and the specific solvent system used.

Interesting facts

Interesting Facts about 2-(Hydroxymethyl)-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-3,4-diol

This compound, often referred to in scientific literature for its unique structural features and properties, belongs to a class of molecules that are pivotal in various biochemical pathways. Here are some intriguing facts:

  • Biological Significance: The compound is known to interact with nucleic acids, which makes it an important subject of study in the field of molecular biology and pharmacology.
  • Structural Complexity: The combination of an imidazopyrine core with a tetrahydrofuran moiety results in a distinct three-dimensional shape that can influence its biological activity.
  • Enzymatic Interactions: Compounds with similar structures have shown the ability to modulate enzyme activity, opening avenues for potential therapeutic applications.
  • Synthetic Pathways: The synthesis of this compound involves advanced organic chemistry techniques, often requiring multi-step procedures to ensure the formation of the desired functional groups.

As a scientist, studying molecules like this one can yield insights into their mechanism of action in biological systems. The density of information that can be gleaned from such complex structures underscores the importance of interdisciplinary collaboration in chemical research.

Quote by a renowned chemist: "Chemistry is not just a science; it's a story waiting to be told through compounds like these." This compound represents a fascinating chapter in the ongoing narrative of chemical discovery and its implications for health and disease.

Synonyms
NoName_4269
CHEMBL4474584
DTXSID70903574
(2R,3S,4R,5R)-2-(HYDROXYMETHYL)-5-{3H-IMIDAZO[2,1-F]PURIN-3-YL}OXOLANE-3,4-DIOL
NSC157740
NSC-157740