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Notoginsenoside R1

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Identification
Molecular formula
C47H80O18
CAS number
145897-68-9
IUPAC name
2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydropyran-3,4,5-triol
State
State

In its pure form at room temperature, Notoginsenoside R1 is typically a solid, appearing as a white crystalline powder.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
514.30
Boiling point (Kelvin)
787.45
General information
Molecular weight
678.93g/mol
Molar mass
678.9300g/mol
Density
1.5500g/cm3
Appearence

This compound appears as a white crystalline powder. It typically has a fine texture and is soluble in water.

Comment on solubility

Solubility of 2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydropyran-3,4,5-triol

The solubility of 2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydropyran-3,4,5-triol (C47H80O18) is a fascinating subject due to its complex structure and numerous functional groups that influence interaction with solvents.

Key Factors Influencing Solubility

  • Hydroxyl Groups: The presence of multiple hydroxyl (–OH) groups significantly enhances the compound's ability to form hydrogen bonds with water, often leading to increased solubility in polar solvents.
  • Hydrophobic Regions: However, the large hydrophobic segments within the molecule may impair its solubility in highly polar solvents, suggesting a preferential solubility in intermediate polar solvents.
  • Temperature: The solubility can also be temperature-dependent; generally, higher temperatures can improve solubility for many compounds.

In summary, while the presence of multiple hydroxyl groups indicates a potential for solubility in polar solvents like water, the overall hydrophobic nature of the compound implies that solubility may be limited. Therefore, careful consideration of the solvent and conditions is necessary when attempting to dissolve this compound.

Interesting facts

Interesting Facts about 2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydropyran-3,4,5-triol

2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydropyran-3,4,5-triol is a unique and fascinating compound that showcases the complexity of organic chemistry. Below are some engaging facts about this compound:

  • Structural Elegance: This compound features a tetrahydropyran ring, which is a cyclic ether that contributes to its structural stability and particular chemical reactivity.
  • Hydroxymethyl Group: The presence of the hydroxymethyl (-CH2OH) group not only enhances solubility but also plays a critical role in the compound's reactivity, enabling it to participate in various chemical transformations.
  • Phenolic Influence: The 4-hydroxyphenoxy moiety adds a layer of functionality, imparting antioxidant properties that can be beneficial in biological systems, making this compound a candidate for further investigation in medicinal chemistry.
  • Natural Products Chemistry: Compounds with similar structures are often found in natural products, indicating potential applications in pharmaceuticals and agrochemicals due to their bioactive properties.

Applications and Potential

This compound's unique structure opens doors to a plethora of applications:

  • Pharmaceutical Development: Due to its antioxidant properties, it may serve as a lead compound in drug discovery, specifically targeting diseases associated with oxidative stress.
  • Cosmetic Industry: Its potential as a stabilizer or active ingredient could revolutionize skincare formulations, where protection against environmental damage is paramount.
  • Research Tool: The compound may be utilized in various biochemical assays to elucidate pathways related to phenolic compounds.

In summary, 2-(Hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydropyran-3,4,5-triol exhibits an intriguing combination of structural complexity and potential applicability across multiple fields. The ongoing study of such compounds continues to giggle the curiosity of both chemists and biologists alike.

Synonyms
4-Hydroxyphenyl hexopyranoside
NSC4036
p-Hydroxyphenyl .beta.-D-glucoside
Hydroquinone .beta.-D-glucopyranoside
p-Hydroxyphenyl .beta.-D-glucopyranoside
.beta.-D-Glucopyranoside, 4-hydroxyphenyl
b-Arbutin
MFCD09838262
.beta.-Arbutin
(c) paragraph sign-Arbutin
SCHEMBL36352
MLS006012040
CHEMBL79041
SCHEMBL20468232
2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
DTXSID20859416
BJRNKVDFDLYUGJ-UHFFFAOYSA-N
HMS1648K06
HMS3655F18
BCP18027
BCP18147
BDBM50130191
STL451054
AKOS001581355
AKOS021730279
AC-8030
4-Hydroxyphenyl .beta.-D-glucopyranoside
DA-35335
SMR001215811
SY051904
SY056800
NS00004042
2-Hydroxymethyl-6-(4-hydroxy-phenoxy)-tetrahydro-pyran-3,4,5-triol