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DMDP

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Identification
Molecular formula
C5H11NO3
CAS number
18947-51-8
IUPAC name
2-(hydroxymethyl)pyrrolidine-3,4-diol
State
State

At room temperature, it exists as a solid, commonly maintained in controlled environments to preserve its chemical stability and integrity.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.15
Boiling point (Celsius)
434.85
Boiling point (Kelvin)
707.85
General information
Molecular weight
149.15g/mol
Molar mass
149.1570g/mol
Density
1.5500g/cm3
Appearence

2-(hydroxymethyl)pyrrolidine-3,4-diol appears as a solid with a crystalline white to off-white appearance. It is crucial in numerous chemical reactions and studies for its unique structure and properties.

Comment on solubility

Solubility of 2-(hydroxymethyl)pyrrolidine-3,4-diol

The compound 2-(hydroxymethyl)pyrrolidine-3,4-diol, with the chemical formula C5H11NO3, exhibits notable solubility characteristics due to its functional groups. The presence of hydroxyl (-OH) groups is key to its solubility in various solvents.

Key Aspects of Solubility:

  • Polar Solvents: This compound dissolves well in polar solvents like water and methanol due to hydrogen bonding capabilities from the hydroxyl groups.
  • Non-Polar Solvents: Conversely, solubility in non-polar solvents is limited due to the compound's polar nature.
  • Temperature Influence: Solubility can also vary with temperature; typically, increased temperature enhances solubility in polar solvents.

As described, the interactions between the hydroxyl groups and solvent molecules lead to a greater solubilization effect. In general terms, "like dissolves like," emphasizing that polar solvents will effectively dissolve this compound better than their non-polar counterparts.

In summary, the solubility of 2-(hydroxymethyl)pyrrolidine-3,4-diol can be characterized as:
Highly soluble in polar solvents
Poorly soluble in non-polar solvents

Interesting facts

Interesting Facts about 2-(Hydroxymethyl)pyrrolidine-3,4-diol

2-(Hydroxymethyl)pyrrolidine-3,4-diol, often referred to in the scientific community by its more systematic name, represents a fascinating intersection of medicinal chemistry and organic synthesis. This compound is notable for several reasons:

  • Biological Relevance: This molecule features a pyrrolidine ring, which is commonly found in many biological systems. Compounds containing this structure often play essential roles in neurotransmission and cellular signaling.
  • Synthetic Utility: The presence of both a hydroxymethyl group and diol functionality makes 2-(hydroxymethyl)pyrrolidine-3,4-diol a valuable intermediate in the synthesis of more complex organic molecules and pharmaceuticals.
  • Chiral Centers: With its distinct stereochemistry, this compound exemplifies the importance of chirality in drug design. The configuration around the pyrrolidine ring can significantly influence the biological activity of the compound.
  • Potential Applications: Owing to its structure, this compound could be a candidate in the development of inhibitors or modulators in various biochemical pathways, making it a target for further research.

In the field of chemistry, the exploration of compounds like 2-(hydroxymethyl)pyrrolidine-3,4-diol exemplifies how small changes in molecular structure can lead to vastly different properties and functions. As scientists continue to study and manipulate these molecules, the potential for therapeutic advancements remains exciting and promising.

As stated by a leading researcher in organic chemistry, "The magic of chemistry lies not just in the molecules themselves, but in how we can unravel their mysteries to develop solutions for real-world problems."

Synonyms
2-(hydroxymethyl)pyrrolidine-3,4-diol
100937-52-8
188925-57-7
2-HYDROXYMETHYL-PYRROLIDINE-3,4-DIOL
2-(Hydroxymethyl)-(2R-(2a,3b,4b))-3,4-Pyrrolidinediol
2-(Hydroxymethyl)-[2R-(2a,3b,4b)]-3,4-Pyrrolidinediol
SCHEMBL981088
1,4-dideoxy-1,4-iminopentitol
OQEBIHBLFRADNM-UHFFFAOYSA-N
HMS3373I18
IMR
3,4-dihydroxy-2-hydroxymethylpyrrolidine
(+)-1,4-Dideoxy-1,4-imino-D-ribitol
2-(Hydroxymethyl)-(2R,3R,4S)-3,4-Pyrrolidinediol