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(2-hydroxyphenyl)(1-piperidinyl)methanethione

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Identification
Molecular formula
C12H15NOS
CAS number
.Not Available
IUPAC name
(2-hydroxyphenyl)-(1-piperidyl)methanethione
State
State

At room temperature, the compound exists as a solid, which may have low volatility under normal conditions.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
375.00
Boiling point (Kelvin)
648.15
General information
Molecular weight
219.32g/mol
Molar mass
219.3200g/mol
Density
1.2370g/cm3
Appearence

The compound is typically a crystalline solid with a characteristic appearance that may be off-white to pale yellow in color. Observing the solid structure would reveal a definite crystalline form, often standard for organic compounds of similar frame.

Comment on solubility

Solubility of (2-hydroxyphenyl)-(1-piperidyl)methanethione

Understanding the solubility of the compound (2-hydroxyphenyl)-(1-piperidyl)methanethione can provide insights into its potential applications and behavior in various environments. Here are some key points regarding its solubility:

  • Polar and Non-Polar Interactions: Given the presence of both a hydroxyl group and a piperidine ring, this compound is expected to engage in both polar and non-polar interactions, making it reasonably versatile in solubility profiles.
  • Solvent Compatibility: The compound may exhibit solubility in a variety of solvents. It is likely to be soluble in polar aprotic solvents such as dimethyl sulfoxide (DMSO) and methanol, while less soluble in non-polar solvents.
  • Influence of Temperature: The solubility may vary significantly with temperature; typically, increased temperatures result in higher solubility for many organic compounds.
  • Hydrogen Bonding: The presence of the hydroxyl group indicates the potential for hydrogen bonding, which could enhance solubility in water-based solutions.

In conclusion, while the solubility of (2-hydroxyphenyl)-(1-piperidyl)methanethione is influenced by its molecular structure, specific data on its solubility is essential for practical applications. It is a fascinating compound that showcases diverse solubility properties based on its functional groups and the solvent environment.

Interesting facts

Interesting Facts About (2-hydroxyphenyl)-(1-piperidyl)methanethione

(2-hydroxyphenyl)-(1-piperidyl)methanethione is a fascinating compound that belongs to the class of thioethers, notable for their versatile biological activity. This compound showcases the intriguing interplay of organic functional groups, leading to a variety of applications in medicinal chemistry.

Key Features:

  • Biological Activity: This compound has been studied for its potential pharmacological properties, including anti-inflammatory and antioxidant effects, making it a candidate for drug development.
  • Structural Composition: The combination of a piperidine ring and a hydroxyphenyl moiety facilitates strong interactions with biological systems, enhancing its effects.
  • Research Interest: Researchers are particularly interested in its role as a chemical probe to elucidate biochemical pathways due to its ability to influence cellular signaling.
  • Environmental Relevance: Investigations into this compound can also extend to its behavior and stability in various environmental settings, highlighting its importance in environmental chemistry.

The study of (2-hydroxyphenyl)-(1-piperidyl)methanethione not only bridges the gap between organic synthesis and pharmacology but also spurs discussions around the development of safer and more effective therapeutic agents.

Future Directions:

As scientists continue to explore its properties, there is potential for this compound to play a significant role in various fields, including:

  • Medicinal Chemistry
  • Drug Design and Development
  • Environmental Science

In conclusion, the research surrounding (2-hydroxyphenyl)-(1-piperidyl)methanethione exemplifies the dynamic nature of chemical investigation, paving the way for new discoveries and innovations in the realm of organic compounds.

Synonyms
N-Piperidinylthiosalicylamide
2032-48-6
1-(Thiosalicyloyl)piperidine
(2-hydroxyphenyl)-piperidin-1-ylmethanethione
PIPERIDINE, 1-(THIOSALICYLOYL)-
Piperidine, 1-((2-hydroxyphenyl)thioxomethyl)-
BRN 0171618
CBMicro_028871
MLS000108075
CHEMBL1327936
CHEBI:121525
FDEJXMBAYGPUFC-UHFFFAOYSA-N
DTXSID701258300
HMS2186K08
2-(1-Piperidinylcarbothioyl)phenol
2-(1-Piperidinylcarbothioyl)phenol #
AKOS000348724
SMR000104038
BIM-0028980.P001
(2-Hydroxyphenyl)-1-piperidinylmethanethione
1-[(2-Hydroxyphenyl)thioxomethyl]piperidine
Methanethione, (2-hydroxyphenyl)-1-piperidinyl-
5-20-03-00066 (Beilstein Handbook Reference)
SR-01000451022
SR-01000451022-1
Q27210079
6-[mercapto(1-piperidinyl)methylidene]-1-cyclohexa-2,4-dienone