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N-(4-Methoxyphenyl)imidazole

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Identification
Molecular formula
C12H12N2O2
CAS number
53718-63-3
IUPAC name
2-imidazol-1-yl-1-(4-methoxyphenyl)ethanone
State
State

At room temperature, this compound is usually in a solid state.

Melting point (Celsius)
86.00
Melting point (Kelvin)
359.15
Boiling point (Celsius)
292.00
Boiling point (Kelvin)
565.15
General information
Molecular weight
202.23g/mol
Molar mass
202.2260g/mol
Density
1.1470g/cm3
Appearence

This compound typically appears as a yellow to tan crystalline solid.

Comment on solubility

Solubility of 2-imidazol-1-yl-1-(4-methoxyphenyl)ethanone

The solubility of 2-imidazol-1-yl-1-(4-methoxyphenyl)ethanone is an intriguing topic due to its complex structure. Understanding its solubility characteristics is essential for both practical applications and theoretical studies. Here are some key points to consider:

  • Polarity: The compound contains a methoxy group which enhances its polar character, suggesting it may have moderate solubility in polar solvents.
  • Solvent Compatibility: It is likely to dissolve well in polar organic solvents such as ethanol or dimethyl sulfoxide (DMSO) but may exhibit lower solubility in non-polar solvents.
  • Hydrogen Bonding: The presence of nitrogen atoms in the imidazole ring can form hydrogen bonds, potentially increasing solubility in protic solvents.
  • Temperature Effects: Like many organic compounds, its solubility may increase with temperature, showcasing higher solubility in heated solvents.

Overall, while specific solubility data might be limited, the predictions based on structural characteristics suggest notable solubility in suitable organic solvents. Understanding these aspects can guide researchers in effectively utilizing 2-imidazol-1-yl-1-(4-methoxyphenyl)ethanone in various chemical applications.

Interesting facts

Interesting Facts about 2-imidazol-1-yl-1-(4-methoxyphenyl)ethanone

2-imidazol-1-yl-1-(4-methoxyphenyl)ethanone is a compound that showcases the fascinating interplay between organic chemistry and medicinal applications. Here are some intriguing facts about this compound:

  • Structural Versatility: This compound features an imidazole ring, which is known for its presence in numerous biological systems, including amino acids and enzymes. The imidazole moiety can interact with various biological targets, making it a key component in pharmacology.
  • Potential Pharmacological Uses: Compounds containing imidazole and phenyl groups have been investigated for their biological activities, including anti-inflammatory, antimicrobial, and antidiabetic properties. Their structures often serve as valuable lead compounds in drug discovery.
  • Electron Donation: The methoxy group (–OCH3) on the phenyl ring can enhance the electron density of the aromatic system. This can significantly influence the compound's reactivity and interactions with biological molecules.
  • Research Potential: Ongoing studies aim to further explore the derivatives of this compound and their potential applications in creating novel therapeutics. The functionalization of heterocycles continues to be a vibrant area of research.
  • Applications in Material Science: Beyond biological applications, imidazole derivatives are also explored in material sciences, such as in the development of advanced organic electronics and as catalysts in various chemical reactions.

In summary, 2-imidazol-1-yl-1-(4-methoxyphenyl)ethanone exemplifies the intricate relationship between chemical structure and functionality. The ongoing exploration of this compound could lead to valuable insights in both medicinal chemistry and material science.

Synonyms
2-imidazol-1-yl-1-(4-methoxyphenyl)ethanone
CHEMBL163689
SCHEMBL8021758
PIIYRILVGMWNKK-UHFFFAOYSA-N
2-(1H-imidazol-1-yl)-4'-methoxyacetophenone