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2-(imidazol-1-yl)-1-phenylethanol

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Identification
Molecular formula
C11H12N2O
CAS number
68111-36-0
IUPAC name
2-imidazol-1-yl-1-phenyl-ethanol
State
State

At room temperature, 2-(imidazol-1-yl)-1-phenylethanol is a solid. It remains stable under normal laboratory conditions but should be stored in a dry environment to prevent moisture uptake.

Melting point (Celsius)
94.00
Melting point (Kelvin)
367.15
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.15
General information
Molecular weight
190.22g/mol
Molar mass
190.2230g/mol
Density
1.1560g/cm3
Appearence

2-(Imidazol-1-yl)-1-phenylethanol typically appears as a white to off-white crystalline solid. Its fine crystalline structure contributes to its well-defined appearance. Due to its chemical structure, it can also exhibit hygroscopic properties, meaning it may absorb moisture from the environment.

Comment on solubility

Solubility of 2-imidazol-1-yl-1-phenyl-ethanol

2-imidazol-1-yl-1-phenyl-ethanol is a fascinating compound with interesting solubility characteristics. Its solubility can be understood through various factors, including polarity, functional groups, and the solvent used.

Solubility Characteristics

This compound is generally characterized as:

  • Polar nature: The presence of the -OH group contributes to its polar characteristics, which often enhances solubility in polar solvents.
  • Solvent-dependent: It tends to be soluble in water and other polar solvents due to hydrogen bonding capabilities, while its solubility in non-polar solvents is significantly reduced.
  • Hydrogen bonding: The ability to form hydrogen bonds allows for better interaction with polar solvents, increasing its solubility.

In summary, 2-imidazol-1-yl-1-phenyl-ethanol is soluble in polar solvents owing to its polar functional groups, making it an intriguing compound for various applications in chemical science.

Interesting facts

Interesting Facts about 2-Imidazol-1-yl-1-phenyl-ethanol

2-Imidazol-1-yl-1-phenyl-ethanol is a fascinating organic compound that intertwines the realms of pharmacology and chemistry. Here are some intriguing insights into this compound:

  • Biological Activity: This compound is known for its potential biological efficacy, particularly in its roles as a ligand. It may interact significantly with various biological targets, making it a subject of interest in drug development.
  • Imidazole Ring: The presence of the imidazole moiety is crucial as it enhances the compound's biological properties. Imidazole is frequently encountered in various bioactive molecules, notably in many enzymatic reactions.
  • Synthetic Versatility: 2-Imidazol-1-yl-1-phenyl-ethanol can be synthesized through various organic reactions, making it a versatile starting compound for the creation of more complex molecules.
  • Reactivity: The hydroxyl group in its structure makes it susceptible to a range of chemical reactions, including oxidation and esterification, broadening its applicability in organic synthesis.
  • Potential Uses: Given its structural features, it holds promise for applications in areas such as medicinal chemistry, material science, and even as a precursor for catalysts.

As echoed by researchers, "The integration of heterocycles like imidazole into molecular scaffolds can significantly enhance biological activity."
This showcases the importance of such compounds in the ongoing quest for new therapeutic agents. The ongoing research into compounds like 2-imidazol-1-yl-1-phenyl-ethanol highlights the endless possibilities within the field of chemistry and its strong linkage to innovation in pharmaceuticals.

Synonyms
24155-47-3
2-(1H-imidazol-1-yl)-1-phenylethanol
RefChem:909060
2-imidazol-1-yl-1-phenylethanol
1-phenyl-2-(1-imidazolyl)ethanol
2-(1-IMIDAZOLYL)-1-PHENYLETHANOL
2-(1H-imidazol-1-yl)-1-phenylethan-1-ol
2-imidazol-1-yl-1-phenyl-ethanol
MFCD00663003
BRN 0151379
alpha-Phenyl-1-imidazoleethanol
IMIDAZOLE-1-ETHANOL, alpha-PHENYL-
N-(beta-Phenyl-beta-hydroxyethyl)imidazole
Benzyl alcohol, alpha-(1-imidazolylmethyl)-
N-((beta-Fenil-beta-idrossi)etil)imidazolo [Italian]
N-((beta-Fenil-beta-idrossi)etil)imidazolo
ChemDiv2_002456
5-23-04-00317 (Beilstein Handbook Reference)
SCHEMBL6173273
CHEMBL1189856
DTXSID50946984
NTWZHQAXJSJOIB-UHFFFAOYSA-N
HMS1375P14
ZAA15547
STK723956
1-(2-hydroxy-2-phenylethyl)imidazole
AKOS001051498
AKOS016353299
2-(1H-1-imidazolyl)-1-phenyl-1-ethanol
ST4075638
EU-0020048
EN300-8524803
Z31334506