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2-Indolin-2-yl-3-phenylpropan-1-ol

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Identification
Molecular formula
C17H19NO
CAS number
970-74-5
IUPAC name
2-indolin-2-yl-3-phenyl-propan-1-ol
State
State

At room temperature, 2-Indolin-2-yl-3-phenylpropan-1-ol is generally in a solid state. It is stable under normal conditions and should be stored in a cool, dry place to maintain its stability and prevent degradation.

Melting point (Celsius)
189.80
Melting point (Kelvin)
462.95
Boiling point (Celsius)
416.50
Boiling point (Kelvin)
689.65
General information
Molecular weight
253.34g/mol
Molar mass
253.3410g/mol
Density
1.1223g/cm3
Appearence

The compound is typically a colorless to pale yellow solid, depending on its purity and specific crystalline form. It may appear as a powder or crystalline solid.

Comment on solubility

Solubility of 2-Indolin-2-yl-3-phenyl-propan-1-ol

The solubility of 2-indolin-2-yl-3-phenyl-propan-1-ol in various solvents can provide interesting insights into its chemical behavior. This compound exhibits unique properties due to its molecular structure, which includes an indole fragment and a hydrophilic alcohol group. Here are some key points regarding its solubility:

  • Polar Solvents: The presence of the hydroxyl (-OH) group typically enhances solubility in polar solvents such as water and alcohols, making it more soluble in these environments.
  • Non-Polar Solvents: Conversely, the indole moiety may lead to limited solubility in non-polar solvents such as hexane or toluene, as the hydrophobic nature outweighs the effect of the alcohol group.
  • Concentrations: Solubility can vary significantly with concentration, temperature, and the presence of other solutes. Increasing temperature may improve solubility in some cases.

It’s important to note that solubility is influenced by several factors, including:

  1. Molecular Interactions: Hydrogen bonding with the solvent can greatly affect the solubility profile of 2-indolin-2-yl-3-phenyl-propan-1-ol.
  2. Structural Considerations: The steric hindrance around the indole structure may also play a role in limiting solubility in certain solvent systems.
  3. pH Levels: The solubility could vary at different pH levels, especially if the compound can undergo protonation or deprotonation.

In conclusion, understanding the solubility of 2-indolin-2-yl-3-phenyl-propan-1-ol is essential for its applications in pharmacology and organic synthesis. Always consult specific solubility data and conduct experiments to determine the most effective solvent for your particular application!

Interesting facts

2-Indolin-2-yl-3-phenyl-propan-1-ol: An Insightful Exploration

2-Indolin-2-yl-3-phenyl-propan-1-ol is a fascinating compound that showcases a unique blend of chemical structures and biological significance. Here are some noteworthy facts that highlight its importance:

  • Structural Complexity: This compound features an indole ring fused with an indolin structure, making it an interesting example of how heterocycles can interact and form new derivatives. Its multi-ring formation can lead to diverse chemical reactivity and applicability.
  • Biological Relevance: Compounds similar to 2-indolin-2-yl-3-phenyl-propan-1-ol have been studied for their potential roles in pharmacology. Many derivatives are known to exhibit significant biological activities, including anticancer and antimicrobial properties, emphasizing the importance of this compound in medicinal chemistry.
  • Synthesis Potential: The synthesis of 2-indolin-2-yl-3-phenyl-propan-1-ol can be achieved through various methods, allowing for modifications that can enhance its properties. This versatility is crucial for researchers aiming to design compound variants tailored for specific applications.
  • Study of Optical Activity: The presence of a chiral center in this compound may lead to interesting optical properties. Scientists are keen on exploring the optical activity of such compounds, as they can have different behaviors when interacting with polarized light, which could have implications in chiral drug design.
  • Applications in Organic Chemistry: Given its structure and properties, this compound can serve as a valuable intermediate in organic synthesis, facilitating the construction of more complex molecules.

In summary, 2-indolin-2-yl-3-phenyl-propan-1-ol is not just another chemical compound; it stands as a testament to the complexity and beauty of organic chemistry, with vast potential for research and application across various scientific fields. As Albert Einstein once said, "Imagination is more important than knowledge." The exploration of such compounds exemplifies how imagination drives scientific progress.

Synonyms
beta-Benzyl-2-indolineethanol
10585-90-7
2-INDOLINEETHANOL, beta-BENZYL-
2-(2,3-dihydro-1H-indol-2-yl)-3-phenylpropan-1-ol
DTXSID80909764