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2-Iodobenzoic acid

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Identification
Molecular formula
C7H5IO2
CAS number
88-67-5
IUPAC name
2-iodobenzoic acid
State
State

At room temperature, 2-iodobenzoic acid is typically a solid.

Melting point (Celsius)
161.20
Melting point (Kelvin)
434.35
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
248.02g/mol
Molar mass
248.0150g/mol
Density
2.0679g/cm3
Appearence

2-Iodobenzoic acid is a white to off-white crystalline powder. It sometimes appears as slightly yellow due to the presence of impurities or exposure to light that can cause a minor degree of decomposition over time.

Comment on solubility

Solubility of 2-Iodobenzoic Acid

2-Iodobenzoic acid, with the chemical formula C7H5I O2, exhibits intriguing solubility characteristics due to its unique structure. Understanding its solubility is essential for various applications, including synthesis and formulation.

Key Points of Solubility:

  • Polar Nature: The presence of the –COOH (carboxylic acid) functional group in 2-iodobenzoic acid contributes to its polar nature, which enhances solubility in polar solvents like water.
  • Temperature Dependence: Like many organic acids, the solubility of 2-iodobenzoic acid is affected by temperature and typically increases with rising temperatures.
  • Solvent Specificity: While 2-iodobenzoic acid is soluble in water, it shows varying degrees of solubility in organic solvents such as ethanol and acetone, depending on their polarity.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules plays a crucial role in its solubility in water.

As a general guideline, one can say that “the solubility of 2-iodobenzoic acid improves in more polar environments.” When considering its practical use, it’s important to account for these factors to achieve optimal solubility in different chemical contexts.

Interesting facts

Interesting Facts about 2-Iodobenzoic Acid

2-Iodobenzoic acid is a fascinating organic compound that exemplifies the intricate world of halogenated aromatic carboxylic acids. Here are some intriguing aspects of this compound:

  • Structural Relationships: The compound features a benzene ring substituted with a carboxylic acid group and an iodine atom at the 2-position, influencing both its physical and chemical properties.
  • Synthesis: It can be synthesized through various pathways, often involving the iodination of benzoic acid, demonstrating valuable reactions in organic synthesis.
  • Reactivity and Applications: Due to the presence of the iodine atom, 2-iodobenzoic acid can serve as a versatile reagent in coupling reactions and various transformations, especially in the formation of biaryl structures.
  • Biological Insights: Compounds similar to 2-iodobenzoic acid are investigated for their potential pharmacological activities, making them significant in drug development research.
  • Environmental Impact: Understanding halogenated compounds like this one is crucial since they can exhibit distinct behaviors in biochemical pathways and environmental systems.

As the renowned chemist Dmitri Mendeleev once said, “What we know is a drop, what we don’t know is an ocean.” This quote is especially relevant for compounds like 2-iodobenzoic acid, illustrating that every molecule opens up new realms of chemistry awaiting exploration. Scientists continue to unravel the mysteries of such compounds, paving the way for innovations in various fields.


In summary, 2-iodobenzoic acid is more than just a chemical entity; it bridges the gap between synthetic methodology and practical applications, underscoring the importance of interdisciplinary research in modern chemistry.

Synonyms
2-IODOBENZOIC ACID
88-67-5
o-Iodobenzoic acid
Benzoic acid, 2-iodo-
Benzoic acid, o-iodo-
Iodobenzoic acid
USAF EK-572
Kyselina o-jodbenzoova
MFCD00002419
o-Jod-benzoesaeure
2-Jod-benzoesaeure
2-Iodo-benzoic acid
Kyselina o-jodbenzoova [Czech]
NSC 3772
EINECS 201-850-7
BRN 1861406
AI3-01811
CHEBI:287979
7Q00V80J7Q
2-(Iodo-(125)I)-benzoic acid
NSC-3772
1321-07-9
DTXSID6058976
O-IODOBENZOIC ACID [MI]
2-iodo benzoic acid
Benzoic acid, iodo-
Progonasyl
UNII-7Q00V80J7Q
oIodobenzoic acid
Benzoic acid, oiodo
Kyselina ojodbenzoova
Benzoic acid, 2iodo
Ortho-iodobenzoic acid
Benzoic acid, 2-iodo
ortho-iodo benzoic acid
2-IODOBENZOICACID
Maybridge1_001326
WLN: QVR BI
2-Iodobenzoic acid, 98%
SCHEMBL40612
2(Iodo(125)I)benzoic acid
CHEMBL112424
DTXCID6048624
HMS545E06
NSC3772
CS-D0909
STR04823
GEO-04834
STK256890
AKOS000119657
BS-4598
CCG-233561
NCGC00336388-01
AC-26054
HY-77433
SRI-10864-03
SY001344
DB-014123
I0053
NS00022866
2-Iodobenzoic acid, purum, >=95.0% (GC)
EN300-18255
A20364
AA-506/30136037
AC-907/25014156
doi:10.14272/CJNZAXGUTKBIHP-UHFFFAOYSA-N.1
Q2535469
2-Iodobenzoic acid, >=99%, purified by sublimation
Z57637028
F0001-2188
201-850-7