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2-Iodophenol

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Identification
Molecular formula
C6H5IO
CAS number
533-58-4
IUPAC name
2-iodophenol
State
State

2-Iodophenol is typically a solid at room temperature.

Melting point (Celsius)
44.00
Melting point (Kelvin)
317.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
220.01g/mol
Molar mass
220.0050g/mol
Density
2.1100g/cm3
Appearence

2-Iodophenol is a light cream to yellow crystalline solid. It may also appear as a powder and has a distinct aromatically iodine-like odor.

Comment on solubility

Solubility of 2-Iodophenol

2-Iodophenol, with the chemical formula C6H5IO, exhibits interesting solubility characteristics that are notable in various solvents. Here are some key points regarding its solubility:

  • Polar Solvents: 2-Iodophenol is moderately soluble in polar solvents such as water and alcohols. The presence of the hydroxyl group (-OH) in its structure enhances its interaction with water molecules, allowing it to dissolve to some extent.
  • Non-Polar Solvents: In contrast, this compound is less soluble in non-polar solvents such as hexane or benzene. The iodophenolic nature reduces its ability to solvate effectively in such environments.
  • Temperature Dependence: It is worth noting that solubility can increase with temperature for some solvents, which means that heating the solution can facilitate higher dissolution rates.
  • pH Influence: The solubility may also be pH-dependent, as the ionization of the hydroxyl group can alter the compound's ability to dissolve in different environments.

In summary, while 2-iodophenol is primarily soluble in polar solvents, its solubility in non-polar environments is significantly limited. Understanding these solubility traits is crucial for applications in synthetic chemistry and material science.

Interesting facts

Interesting Facts about 2-Iodophenol

2-Iodophenol is a fascinating compound that belongs to the class of phenols, specifically characterized by the presence of an iodine atom on the benzene ring. Here are some intriguing aspects of this compound:

  • Biological Significance: 2-Iodophenol plays a role in various biochemical reactions. It can be used as a precursor in the synthesis of more complex pharmaceuticals and agrochemicals, highlighting its utility in medicinal chemistry.
  • Substituted Phenols: As a substituted phenol, 2-iodophenol has distinct properties compared to its non-substituted counterparts. The introduction of the iodine atom influences both its chemical reactivity and its interaction with biological systems.
  • Analytical Applications: This compound is commonly employed in analytical chemistry, particularly in the identification and quantification of phenolic compounds due to its unique spectral properties.
  • Research Utilization: Various research studies explore its application in organic synthesis. The iodine substituent can facilitate nucleophilic reactions, making it a valuable building block in synthetic organic chemistry.
  • Sustainability Perspective: In recent years, there has been a growing interest in utilizing 2-iodophenol as a sustainable alternative in chemical reactions, providing environmentally friendly pathways to synthesize valuable compounds.

In conclusion, 2-Iodophenol is not just a simple compound; it serves as a vital link in many chemical processes and scientific explorations. Its unique properties and versatility in applications make it a subject of great interest for chemists and researchers alike.

Synonyms
2-IODOPHENOL
533-58-4
o-Iodophenol
Phenol, 2-iodo-
Phenol, o-iodo-
o-Jodphenol
o-Jodfenol
2-Jodfenol
o-Jodfenol [Czech]
2-Jodfenol [Czech]
2-Jodphenol
NSC 9245
EINECS 208-569-9
BRN 1855300
CHEBI:16706
F27L34A8B9
NSC-9245
O-IODOPHENOL [MI]
DTXSID5052175
4-06-00-01070 (Beilstein Handbook Reference)
oJodfenol
2iodophenol
ortho-iodophenol
2Jodfenol
Phenol, oiodo
Phenol, 2iodo
DTXCID5030745
208-569-9
inchi=1/c6h5io/c7-5-3-1-2-4-6(5)8/h1-4,8
2-iodanylphenol
MFCD00013963
Iodophenol
30587-23-6
Phenol, iodo-
NSC 9245; o-Iodophenol;
UNII-F27L34A8B9
2-iodo phenol
2-iodo-phenol
2-Iodophenol (2IP)
2-Iodophenol, 98%
WLN: QR BI
SCHEMBL5720
CHEMBL225564
NSC9245
BDBM217397
STR06375
STL280542
AKOS009156984
AC-4390
CS-W008896
PS-7876
BP-21314
SY005097
DB-014125
I0460
NS00032730
EN300-39648
C01874
H11264
A829536
Q27102035
Z384970702
6X8