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2-Isobutyl-3-methoxypyrazine

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Identification
Molecular formula
C10H16N2O
CAS number
24683-00-9
IUPAC name
2-isobutyl-3-methoxy-pyrazine
State
State

At room temperature, 2-Isobutyl-3-methoxypyrazine is a liquid. The compound's aromatic characteristics are significant enough to impact the sensory properties of a variety of foods and beverages, including wines.

Melting point (Celsius)
-30.00
Melting point (Kelvin)
243.15
Boiling point (Celsius)
191.00
Boiling point (Kelvin)
464.15
General information
Molecular weight
166.23g/mol
Molar mass
166.2250g/mol
Density
0.9845g/cm3
Appearence

2-Isobutyl-3-methoxypyrazine appears as a clear, colorless to pale yellow liquid that possesses an intensely strong earthy, green bell pepper-like odor. This compound is known for its powerful fragrance, which is perceptible even at very low concentrations.

Comment on solubility

Solubility of 2-isobutyl-3-methoxy-pyrazine

2-isobutyl-3-methoxy-pyrazine, a compound often used in flavor and fragrance applications, displays interesting solubility characteristics that merit discussion. The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of a methoxy group (-OCH3) introduces polarity, which may enhance solubility in polar solvents.
  • Hydrophobic interactions: The isobutyl group contributes hydrophobic characteristics, leading to potential solubility in nonpolar solvents.
  • Temperature: Solubility often increases with temperature, making it more soluble in warmer conditions.
  • pH Levels: The pH of the environment can also impact the ionization of the compound, thus affecting solubility.

In practice, 2-isobutyl-3-methoxy-pyrazine is expected to be more soluble in organic solvents such as ethanol or ether, while its solubility in water may be limited due to its hydrophobic characteristics. The balance between its polar and nonpolar features plays a critical role in determining the suitable solvent for effective dissolution.

As with many organic compounds, understanding the solubility of 2-isobutyl-3-methoxy-pyrazine is essential for its applications, whether in flavoring agents or as a synthetic building block in chemical processes.

Interesting facts

Interesting Facts about 2-Isobutyl-3-methoxy-pyrazine

The compound 2-isobutyl-3-methoxy-pyrazine is a fascinating aromatic compound that belongs to the class of pyrazines, which are heterocyclic compounds known for their distinctive properties and aromas. Here are some notable points about this compound:

  • Aromatic Character: This compound contributes a unique flavor profile, often described as earthy and nutty, making it valuable in the food industry as a flavoring agent.
  • Occurrence: Naturally occurring in various food products, it can be found in roasted coffee, cocoa, and certain types of spices, enhancing their overall sensory experience.
  • Odor Threshold: With a very low odor threshold, only a minute concentration is needed to deliver its characteristic scent, which reflects the potent nature of such compounds in flavor and fragrance formulations.
  • Biological Activity: Some studies suggest that pyrazines may exhibit antioxidant properties, providing potential health benefits, which are an exciting area of research in food chemistry.
  • Synthesis: The synthesis of 2-isobutyl-3-methoxy-pyrazine can be achieved through various organic reactions, showcasing the versatility of pyrazine derivatives in medicinal and industrial chemistry.
  • Wide-ranging Applications: Beyond its use in food, this compound is also explored in the fragrance industry, where it aids in creating complex scent profiles for perfumes.

As a student of chemistry or a research scientist, it's intriguing to consider how such a seemingly simple compound can have extensive implications in various fields. Exploring the nuances of 2-isobutyl-3-methoxy-pyrazine offers a glimpse into the interconnected world of chemistry, flavor, and biology.

Synonyms
2-ISOBUTYL-3-METHOXYPYRAZINE
24683-00-9
2-Methoxy-3-(2-methylpropyl)pyrazine
3-Isobutyl-2-methoxypyrazine
2-Methoxy-3-isobutylpyrazine
Pyrazine, 2-methoxy-3-(2-methylpropyl)-
FEMA No. 3132
DTXSID9051907
Pyrazine, 2-isobutyl-3-methoxy-
S327O0T12O
DTXCID4030469
RefChem:473806
246-402-1
2-methoxy-3-isobutyl pyrazine
1dzk
MFCD00006128
2-Isobutyl-3-methoxy-pyrazine
IBMP
3-methoxy-2-isobutylpyrazine
Pyrazine, 2-isobutyl-3-methoxy
Pyrazine, 2-methoxy, 3-isobutyl
2-Methoxy-3-(2-methyl-propyl) pyrazine
Pyrazine, 2-(2-methylpropyl)-3-methoxy
Pyrazine, 3-methoxy-2-(2-methylpropyl)
PRZ
2-Isobutyl-3-methoxypyrazine 100 microg/mL in Methanol
Galbazine
UNII-S327O0T12O
2nnd
EINECS 246-402-1
1qy1
2-Methoxy-3isobutylpyrazine
CHEMBL97355
SCHEMBL113424
orb1944999
SCHEMBL29466583
BDBM12031
FEMA 3132
UXFSPRAGHGMRSQ-UHFFFAOYSA-
MSK2928
CHEBI:229442
HY-W017141R
2-Isobutyl-3-methoxypyrazine, 8CI
Tox21_303996
2-Isobutyl-3-methoxypyrazine, 99%
AKOS015837530
CS-W017857
DB04512
DS-4663
FI63381
HY-W017141
2-methoxy-3-(2-methylpropyl)-pyrazine
2-Isobutyl-3-methoxypyrazine (Standard)
NCGC00357216-01
PD006042
SY015681
CAS-24683-00-9
DB-021268
DB-293209
DB-314100
2-ISOBUTYL-3-METHOXYPYRAZINE [FHFI]
2-Isobutyl-3-methoxypyrazine, >=99%, FG
I0331
NS00012682
ST50307154
83M009
2-Isobutyl-3-methoxypyrazine, analytical standard
A817435
F150700
Q15633924
InChI=1/C9H14N2O/c1-7(2)6-8-9(12-3)11-5-4-10-8/h4-5,7H,6H2,1-3H3