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Procaine hydrochloride

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Identification
Molecular formula
C13H21ClN2O2
CAS number
51-05-8
IUPAC name
2-(isobutylamino)ethyl 3-aminobenzoate;hydrochloride
State
State

At room temperature, Procaine hydrochloride is in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
272.77g/mol
Molar mass
272.7700g/mol
Density
1.1700g/cm3
Appearence

Procaine hydrochloride typically appears as a white crystalline powder. It is odorless and has a slightly bitter taste. This compound is highly soluble in water which makes it easy to prepare in solution form.

Comment on solubility

Solubility of 2-(isobutylamino)ethyl 3-aminobenzoate;hydrochloride

The solubility of 2-(isobutylamino)ethyl 3-aminobenzoate;hydrochloride in various solvents is a critical aspect of its chemical behavior. Generally, this compound exhibits the following solubility characteristics:

  • In Water: Being a hydrochloride salt, it is expected to be highly soluble in water due to the ionic nature of the salt which promotes solvation.
  • In Organic Solvents: It may show variable solubility, often being less soluble in non-polar solvents. Typical organic solvents such as ethanol or methanol might allow for adequate solubility due to potential hydrogen bonding.
  • Temperature Effects: Increased temperature could further enhance solubility, allowing for a better dissolution in both water and organic solvents.

It is interesting to note that the pH of the solution can also dramatically affect the solubility of this compound. As the solution becomes more acidic, the compound may exist in its protonated form, thereby enhancing its solubility in aqueous environments.

In summary, understanding the solubility properties of 2-(isobutylamino)ethyl 3-aminobenzoate;hydrochloride is essential for its applications in pharmaceuticals and chemical synthesis. The compound's potential applications can often be limited by its solubility profile, leading to further investigations to optimize formulations and delivery mechanisms.

Interesting facts

Interesting Facts About 2-(isobutylamino)ethyl 3-aminobenzoate; hydrochloride

This compound, often referred to in the scientific community for its role in medicinal chemistry, exhibits several fascinating characteristics that make it a subject of interest for researchers and students alike. Here are some noteworthy points:

  • Therapeutic Applications: This compound is primarily studied for its potential use as a drug. It may exhibit activities that target specific biological pathways, making it a candidate for further pharmaceutical development.
  • Structure-Activity Relationship: The unique combination of the isobutylamino group and the 3-aminobenzoate structure allows scientists to explore how modifications in the molecular structure can affect biological activity, leading to valuable insights into drug design.
  • Chiral Centers: The presence of chiral centers in the compound opens up discussions about stereochemistry and how the orientation of molecules can influence their interactions in biological systems.
  • Research Interest: Ongoing studies around this compound focus on its receptors and pharmacokinetics, which can be particularly fascinating for those interested in how drugs interact at the molecular level.
  • Role in Organic Synthesis: As a versatile building block, this compound can serve as an intermediate in organic synthesis, highlighting its importance in the chemical industry beyond medicinal applications.

As one delves into the study of 2-(isobutylamino)ethyl 3-aminobenzoate; hydrochloride, it's essential to appreciate its multifaceted roles in both academic research and pharmaceutical development. “The beauty of chemistry lies in its ability to connect molecules to life,” and this compound exemplifies that connection through its promising applications and intriguing structural attributes.

Synonyms
Metabutethamine hydrochloride
Metabutethamine HCl
Unacaine hydrochloride
553-58-2
2-Isobutylaminoethyl m-aminobenzoate hydrochloride
Metabutethamine hydrochloride [NF]
UNII-36IME48STO
Butethamine meta-isomer hydrochloride
36IME48STO
NSC 41532
NSC-41532
2-(Isobutylamino)ethanol m-aminobenzoate hydrochloride
DTXSID30203825
Benzoic acid, m-amino-, 2-isobutyl aminoethyl ester, hydrochloride
ETHANOL, 2-(ISOBUTYLAMINO)-, m-AMINOBENZOATE (ester), MONOHYDROCHLORIDE
Ethanol, 2-((2-methylpropyl)amino)-, 3-aminobenzoate (ester), monohydrochloride
BUTETHAMINE META-ISOMER HYDROCHLORIDE [MI]
2-(ISOBUTYLAMINO)ETHANOL M-AMINOBENZOATE, HYDROCHLORIDE
DTXCID60126316
Benzoic acid, m-amino-, 2-isobutyl aminoethyl ester, hydrochloride (6CI)
Ethanol, 2-((2-methylpropyl)amino)-, 3-aminobenzoate (ester), monohydrochloride (9CI)
Unacaine
2-(2-methylpropylamino)ethyl 3-aminobenzoate;hydrochloride
CHEMBL2106833
NSC41532
Ethanol, 3-aminobenzoate (ester), monohydrochloride
Ethanol, m-aminobenzoate (ester), monohydrochloride
Q27256570