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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
2-(isobutylamino)ethyl 4-aminobenzoate
State
State
Procaine is typically a solid at room temperature in the form of a white powder. It is odorless and stable under normal conditions.
Melting point (Celsius)
61.00
Melting point (Kelvin)
334.00
Boiling point (Celsius)
378.60
Boiling point (Kelvin)
651.80
General information
Molecular weight
236.31g/mol
Molar mass
236.3110g/mol
Density
1.1000g/cm3
Appearence

Procaine is typically found as a white crystalline powder that has great solubility in water but poor solubility in alcohol and in oils. Its texture and physical composition are similar to that of many pharmaceutical-grade powders.

Comment on solubility

Solubility of 2-(isobutylamino)ethyl 4-aminobenzoate

The solubility of 2-(isobutylamino)ethyl 4-aminobenzoate can be influenced by several factors, including its structure and the interactions it has with solvents. This compound is known to contain both amino and ester functional groups, which can significantly affect its solubility in various environments.

Typically, the components contributing to its solubility are:

  • Amino Group: Allows for hydrogen bonding with polar solvents like water, potentially increasing solubility.
  • Ester Linkage: This part of the molecule can attract solvents of varying polarity, possibly aiding in dissolution.
  • Hydrophobic Isobutyl Group: The presence of this alkyl chain may decrease solubility in highly polar solvents while enhancing it in non-polar environments.

Overall, the solubility characteristics can be summarized as:

  • Moderate solubility in polar solvents such as water.
  • Increased solubility in organic solvents due to hydrophobic interactions.
  • "Like dissolves like" principle applies, making this compound more compatible with solvents that have similar polarities.

For practical applications, determining the exact solubility requires empirical testing under specified conditions, as real-world factors such as temperature and pH may also play significant roles.

Interesting facts

Interesting Facts about 2-(Isobutylamino)ethyl 4-Aminobenzoate

2-(Isobutylamino)ethyl 4-aminobenzoate is a fascinating compound that plays a significant role in medicinal chemistry. Here are some intriguing aspects:

  • Pharmaceutical Relevance: This compound is often researched for its potential applications in drug design, particularly as an analgesic and anti-inflammatory agent.
  • Structure-Activity Relationship (SAR): The presence of the isobutylamino group significantly impacts the pharmacological properties, enhancing its ability to interact with specific biological targets.
  • Mechanism of Action: Studies suggest that compounds like this one may work by inhibiting certain enzymes or receptors in the body, which is crucial for developing effective therapies.
  • Synthesis Techniques: The synthesis of this compound often involves multiple steps, including amination and esterification, making it a great example of complex organic synthesis.

Research into this compound continues to reveal more about its properties and potential benefits. As scientists uncover new findings, we may see its applications expand, contributing to advancements in healthcare and pharmaceuticals.

In summary, 2-(isobutylamino)ethyl 4-aminobenzoate is not just another chemical; it represents the intersection of chemistry and medicine, showcasing how intricate molecular structures can lead to important health solutions.

Synonyms
BUTETHAMINE
2090-89-3
Monocain
Ibylcaine
F8E12S0YYS
BUTETHAMINE [MI]
UNII-F8E12S0YYS
2-(Isobutylamino)ethyl p-aminobenzoate
BUTETHAMINE [WHO-DD]
Isobutylaminoethyl p-aminobenzoate
DTXSID30175053
2-(Isobutylamino)ethanol p-aminobenzoate (ester)
Ethanol, 2-(isobutylamino)-, p-aminobenzoate (ester)
Ethanol, 2-[(2-methylpropyl)amino]-, 4-aminobenzoate (ester)
2-[(2-Methylpropyl)amino]ethanol 4-aminobenzoate
2-[(2-Methylpropyl)amino]ethanol 4-aminobenzoate (ester)
2-((2-METHYLPROPYL)AMINO)ETHANOL 4-AMINOBENZOATE (ESTER)
2-((2-Methylpropyl)amino)ethanol 4-aminobenzoate
Ethanol, 2-((2-methylpropyl)amino)-, 4-aminobenzoate (ester)
DTXCID4097544
wdictqvbxkadbp-uhfffaoysa-n
2-(2-methylpropylamino)ethyl 4-aminobenzoate
Isobutylaminoethyl p-aminobenzoate; Monocain
SCHEMBL24618
CHEMBL124211
CHEBI:134959
BDBM50225498
2-(Isobutylamino)ethyl 4-aminobenzoate #
NS00113995
Q27277810