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Procaine hydrochloride

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Identification
Molecular formula
C13H21ClN2O2
CAS number
51-05-8
IUPAC name
2-(isobutylamino)ethyl 4-aminobenzoate;hydrochloride
State
State

At room temperature, procaine hydrochloride is a solid. Due to its crystalline nature, it is particularly stable and easy to handle in a laboratory or compounding environment. It is typically stored in a dry, cool location to maintain its stability over time.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.15
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.15
General information
Molecular weight
273.80g/mol
Molar mass
273.7980g/mol
Density
1.1700g/cm3
Appearence

Procaine hydrochloride usually appears as a white crystalline powder. It is odorless and has a slightly bitter taste. The compound is soluble in water and ethanol, making it easy to dissolve when needed for formulating solutions. The fine, clean appearance of the crystals is typical of pharmaceutical-grade anesthetics.

Comment on solubility

Solubility of 2-(isobutylamino)ethyl 4-aminobenzoate; hydrochloride

The solubility of 2-(isobutylamino)ethyl 4-aminobenzoate; hydrochloride is an important consideration for its application and handling. This compound typically exhibits good solubility in water due to the presence of the hydrochloride group, which enhances its ionic nature. Here are some key points regarding its solubility:

  • Water Solubility: Generally soluble in water, making it suitable for various aqueous applications.
  • Polar Solvents: It may also dissolve well in polar organic solvents, which can aid in formulation processes.
  • Non-polar Solvents: Limited solubility in non-polar solvents, suggesting that its use may be less effective in such environments.
  • pH Dependence: Solubility can be influenced by the pH of the solution, as the charges on the amino groups can interact with protons.

As emphasized in chemical practice, "the solubility of a compound dictates its usability in biological and pharmaceutical contexts." Understanding these solubility characteristics is crucial for optimizing the formulation and ensuring effective delivery.

Interesting facts

Interesting Facts about 2-(Isobutylamino)ethyl 4-aminobenzoate; hydrochloride

2-(Isobutylamino)ethyl 4-aminobenzoate, also known in its hydrochloride form, is a fascinating compound that showcases a blend of aromatic and aliphatic properties. Here are some intriguing aspects of this chemical:

  • Pharmaceutical Relevance: This compound is often evaluated in the realm of medicinal chemistry due to its potential roles in drug formulation and therapeutic applications. Compounds similar to it have been recognized for their ability to modulate biological systems.
  • Structure-Activity Relationship: Researchers are particularly interested in how variations in the molecular structure of this compound can affect its biological activity. Understanding this relationship is critical in designing effective pharmaceutical agents.
  • Surface Activity: The presence of both an amino group and an aromatic ring can influence the compound's interactions with biological membranes, making it a subject for studies in biochemistry.
  • Synthesis Research: The synthesis of 2-(isobutylamino)ethyl 4-aminobenzoate can lead to various derivatives, which may possess unique or enhanced properties compared to the parent compound. Synthetic routes continue to be explored by chemists looking to optimize yields and efficacy.
  • Comparative Analysis: Compounds with similiar moieties are often compared in terms of their pharmacokinetic profiles. This compound's unique characteristics could pave the way for innovations in drug design.

As stated in classic texts, "The beauty of chemistry lies in its complexity and simplicity," and 2-(isobutylamino)ethyl 4-aminobenzoate embodies this duality. Whether through its structural characteristics or its applications in the field of medicine, this compound continues to intrigue scientists and inspire new research.

Synonyms
Butethamine hydrochloride
Butethamine HCl
553-68-4
Ibylcaine hydrochloride
Monocaine hydrochloride
IBYLCAINE CHLORIDE
Butethamine hydrochloride [NF]
2-(Isobutylamino)ethyl p-aminobenzoate hydrochloride
NSC-10821
0M63DKI91K
WLN: ZR DVO2M1Y1&1
2-(2-methylpropylamino)ethyl 4-aminobenzoate;hydrochloride
Ethanol, 2-[(2-methylpropyl)amino]-, 4-aminobenzoate (ester),monohydrochloride
Ethanol, p-aminobenzoate (ester), monohydrochloride
NSC 10821
UNII-0M63DKI91K
Monocaine
2-(Isobutylamino)ethanol hydrochloric acid salt, p-aminobenzoic acid ester
p-Aminobenzoic acid ester of 2-(isobutylamino)ethanol hydrochloric acid salt
p-Aminobenzoic acid 2-(isobutylamino)ethyl ester hydrochloride
Benzoic acid, p-amino-, 2-(isobutylamino)ethyl ester, hydrochloride
2-Isobutylaminoethanol hydrochloric acid salt, p-aminobenzoic acid ester
p-Aminobenzoic acid ester of 2-isobutylaminoethanol hydrochloric acid salt
CHEMBL2106151
SCHEMBL11696815
DTXSID90203826
NSC10821
NSC41483
NSC41533
NSC-41483
NSC-41533
BUTETHAMINE HYDROCHLORIDE [MI]
Ethanol, 2-((2-methylpropyl)amino)-, 4-aminobenzoate (ester), monohydrochloride
ETHANOL, 2-(ISOBUTYLAMINO)-, p-AMINOBENZOATE (ESTER), MONOHYDROCHLORIDE
BUTETHAMINE HYDROCHLORIDE [WHO-DD]
Q27236961
p-Aminobenzoate, 2-(isobutylamino)ethyl-, hydrochloride