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Metronidazole

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Identification
Molecular formula
C6H9N3O3
CAS number
443-48-1
IUPAC name
2-isopropyl-1-methyl-5-nitro-imidazole
State
State

At room temperature, metronidazole is in a solid state.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
171.15g/mol
Molar mass
171.1530g/mol
Density
1.4500g/cm3
Appearence

Metronidazole appears as a white to yellowish crystalline powder. It is usually odorless, but may have a slight characteristic odor.

Comment on solubility

Solubility of 2-isopropyl-1-methyl-5-nitro-imidazole

2-isopropyl-1-methyl-5-nitro-imidazole is a fascinating compound when it comes to its solubility characteristics. The solubility of this compound can vary significantly based on several factors including temperature, the solvent used, and the presence of other solutes. Here are some key points to consider:

  • Solvent Compatibility: The polar nature due to the nitro group influences its solubility in polar solvents like water. However, the bulky isopropyl and methyl groups suggest better solubility in non-polar organic solvents.
  • Temperature Dependency: As is common with many organic compounds, solubility may increase with temperature, allowing for higher concentrations in solution as thermal energy facilitates interactions.
  • pH Influence: Since imidazole derivatives can be affected by pH, the ionic state of the compound may change, affecting its solubility. In acidic or basic environments, solubility could potentially enhance due to ionization.

In summary, while 2-isopropyl-1-methyl-5-nitro-imidazole demonstrates moderate solubility, its behavior in various solvents and conditions highlights the intricate relationship between chemical structure and solubility. Understanding these aspects is crucial when considering its applications in chemical processes.

Interesting facts

Interesting Facts about 2-Isopropyl-1-methyl-5-nitro-imidazole

2-Isopropyl-1-methyl-5-nitro-imidazole is a fascinating chemical compound that has captured the attention of researchers due to its unique structure and potential applications. Here are some noteworthy insights:

  • Unique Structure: This compound belongs to the imidazole family, which are five-membered aromatic rings containing two nitrogen atoms. Its structure allows for interesting interactions, making it a candidate for various studies in pharmaceuticals.
  • Pharmaceutical Significance: Compounds in the imidazole class are known for their biological activity. They can act as antifungal agents, which makes 2-isopropyl-1-methyl-5-nitro-imidazole a potential subject for further exploration in medicinal chemistry.
  • Research Potential: Ongoing research may uncover new applications for this compound in drug development. Scientists are keen on studying how modifications to its structure can enhance its efficacy and safety profiles.
  • Versatile Functional Groups: The presence of the isopropyl and nitro groups infers unique reactivity patterns. The nitro group can influence the compound's electronic properties, and the isopropyl group provides steric hindrance, which can impact its interaction with biological targets.
  • Environmental Impact: As with many nitrogen-containing compounds, the synthesis and degradation processes may have environmental implications. Understanding these factors is crucial for assessing the compound's sustainability.

In conclusion, 2-isopropyl-1-methyl-5-nitro-imidazole represents a noteworthy example of how organic compounds can combine various functional groups to produce molecules with potential therapeutic properties. By continuing to study its characteristics and applications, chemists can unlock new possibilities in both biology and chemistry.

Synonyms
IPRONIDAZOLE
14885-29-1
1H-Imidazole, 1-methyl-2-(1-methylethyl)-5-nitro-
2-Isopropyl-1-methyl-5-nitroimidazole
Ipronidazol
Ro 7-1554
Ipronidazolo
Ipronidazolum
NSC-109212
DTXSID7046839
NSC109212
Ro-71554
045BU63E23
RO-7-1554
DTXCID5026839
238-957-3
Ipropran
1-methyl-5-nitro-2-propan-2-ylimidazole
Ro 07-1554
Imidazole, 2-isopropyl-1-methyl-5-nitro-
1H-Imidazole, 2-isopropyl-1-methyl-5-nitro-
NSC 109212
M+B 16905
1-Methyl-2-(1-methylethyl)-5-nitro-1H-imidazole
NCGC00181095-01
Ipronidazolo [DCIT]
Ipronidazol [INN-Spanish]
Ipronidazolum [INN-Latin]
Ipronidazile (1000 ug/mL in Methanol)
1-Methyl-2-isopropyl-5-nitroimidazole
EINECS 238-957-3
BRN 0744577
Ipronidazole [USAN:INN:BAN]
UNII-045BU63E23
2-Isopropyl-1-methyl-5-nitro-1H-imidazole
IPRONIDAZOLE [MI]
Ipronidazole (USAN/INN)
IPRONIDAZOLE [INN]
IPRONIDAZOLE [USAN]
IPRONIDAZOLE [MART.]
SCHEMBL159633
CHEMBL334786
orb2695741
IPRONIDAZOLE [GREEN BOOK]
MSK5542
CHEBI:181451
Tox21_112711
AKOS006271453
FM24647
2-Isopropyl-1-methyl-5- nitroimidazole
2-isopropyl-1-methyl-5-nitro-imidazole
NCGC00181095-02
CAS-14885-29-1
HY-151217
NS00010365
2-Isopropyl-1-methyl-5-nitro-1H-imidazole #
D04608
H37432
Ipronidazole, VETRANAL(TM), analytical standard
1-methyl-5-nitro-2-(propan-2-yl)-1H-imidazole
Q6065435
5-(Hydroxy(oxido)amino)-2-isopropyl-1-methyl-1H-imidazole
1-Methyl-2-(1-methylethyl)-5-nitro-1H-imidazole;Ipronidazole
N-(3-methyl-2-propan-2-ylimidazol-4-yl)-N-oxidohydroxylamine
InChI=1/C7H11N3O2/c1-5(2)7-8-4-6(9(7)3)10(11)12/h4-5H,1-3H