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2-isopropylbenzimidazole

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Identification
Molecular formula
C10H12N2
CAS number
89284-27-9
IUPAC name
2-isopropyl-1H-benzimidazole
State
State

At room temperature, 2-isopropylbenzimidazole is typically in a solid state. It exists as crystalline solids that are stable under normal conditions. Proper storage is needed to maintain its integrity and prevent any undue reactions.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
160.22g/mol
Molar mass
160.1990g/mol
Density
1.0300g/cm3
Appearence

2-isopropylbenzimidazole typically appears as a crystalline solid. It is colorless to light yellow in hue, depending on the level of purity. The compound might form needle-like crystals when properly crystallized, and it often exhibits a slight aromatic odor characteristic of benzimidazole derivatives.

Comment on solubility

Solubility of 2-isopropyl-1H-benzimidazole

2-isopropyl-1H-benzimidazole is a chemical compound that exhibits interesting solubility characteristics. Understanding its solubility is essential for applications in various fields such as pharmaceuticals and materials science.

Key Factors Influencing Solubility:

  • Polarity: The solubility of 2-isopropyl-1H-benzimidazole may be influenced by its polar and nonpolar interactions within solvents.
  • Solvent Type: Typically, benzimidazole derivatives tend to be more soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and chloroform, while exhibiting limited solubility in water.
  • Temperature: Increased temperature often enhances the solubility of solid compounds in liquids, which might also apply to this compound.

In summary, while 2-isopropyl-1H-benzimidazole may demonstrate moderate solubility in nonpolar solvents, it is crucial to consider the solvent environment and temperature. Its behavior showcases the complex interplay of molecular structure and solvation dynamics, making it a compound of interest for further study in solubility behavior.

Interesting facts

Interesting Facts about 2-Isopropyl-1H-benzimidazole

2-Isopropyl-1H-benzimidazole is a fascinating compound with various applications in the realm of chemistry and pharmaceuticals. Here are some noteworthy points to consider:

  • Pharmaceutical Applications: This compound has garnered attention for its potential use in medicinal chemistry. It serves as an intermediate in the synthesis of various pharmaceutical agents, specifically those targeting fungal and bacterial infections.
  • Mechanism of Action: 2-Isopropyl-1H-benzimidazole functions primarily by inhibiting the activity of specific enzymes necessary for the survival of pathogens. This mechanism makes it a valuable candidate for developing new therapeutic agents.
  • Structural Significance: The benzimidazole moiety itself is known for its ability to engage in hydrogen bonding and π-stacking interactions, greatly influencing the biological activity of compounds that contain it.
  • Research Interest: Ongoing research is focused on optimizing its structure to enhance its efficacy and selectivity. This compound serves as a significant scaffold for drug discovery.
  • Multi-Faceted Uses: Besides its pharmaceutical applications, 2-isopropyl-1H-benzimidazole finds utility in other areas, such as agricultural chemistry and material science, proving to be a versatile compound.

In conclusion, the interest in 2-isopropyl-1H-benzimidazole lies not only in its chemical properties but also in its contributions to the advancement of multiple scientific fields. As more discoveries unfold, this compound may play a crucial role in shaping the future of medicinal chemistry.

Synonyms
2-ISOPROPYLBENZIMIDAZOLE
2-(propan-2-yl)-1H-1,3-benzodiazole
676-582-0
5851-43-4
2-isopropyl-1H-benzo[d]imidazole
2-Isopropyl-1H-benzimidazole
1H-Benzimidazole, 2-(1-methylethyl)-
Benzimidazole, 2-isopropyl-
2-propan-2-yl-1H-benzimidazole
MFCD00051759
CHEMBL368344
BRN 0003535
2-isopropyl-1H-1,3-benzodiazole
Maybridge1_003611
SCHEMBL85832
5-23-06-00501 (Beilstein Handbook Reference)
2-Isopropyl-1H-benzoimidazole
F0853-0050
2-Isopropyl-1H-benzimidazole #
HMS551M03
DTXSID50207229
CHEBI:194842
ALBB-014699
2-(propan-2-yl)-1H-benzimidazole
BDBM50404927
STK866208
AKOS000275098
PS-4863
2-Isopropyl-1H-benzimidazole, AldrichCPR
DP 01004
2-ISOPROPYL-1H-1,3-BENZIMIDAZOLE
DB-025903
CS-0117015
EN300-16228
A15278
F13441
Z50129788