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Ipidacrine

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Identification
Molecular formula
C18H25NO2Cl
CAS number
62719-28-4
IUPAC name
2-isopropyl-2-(1-naphthyl)-5-piperidin-1-ium-1-yl-pentanoic acid;chloride
State
State

At room temperature, ipidacrine is in a solid state as a crystalline powder. It is stable under common conditions and suitable for handling in a laboratory setting.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
252.00
Boiling point (Kelvin)
525.15
General information
Molecular weight
252.35g/mol
Molar mass
252.3510g/mol
Density
1.2134g/cm3
Appearence

Ipidacrine appears as a fine crystalline powder. It is typically off-white to pale yellow in color.

Comment on solubility

Solubility of 2-isopropyl-2-(1-naphthyl)-5-piperidin-1-ium-1-yl-pentanoic acid;chloride

The solubility of 2-isopropyl-2-(1-naphthyl)-5-piperidin-1-ium-1-yl-pentanoic acid;chloride is an important characteristic to consider for its applications in both medicinal and chemical fields. This compound is an example of a quaternary ammonium salt, which typically exhibits unique solubility properties.

  • Solubility in Water: Compounds like this often have moderate to high solubility in water, due to their ionic nature. However, the presence of bulky aromatic rings can impede solubility to some extent.
  • Solubility in Organic Solvents: Generally, such compounds are more soluble in polar organic solvents, allowing for utilization in various organic reactions.
  • Factors Affecting Solubility: The solubility can be influenced by temperature and the presence of other ions in solution, which can either enhance or reduce overall solubility.

As a general rule, the solubility of ionic compounds like chlorides tends to increase in systems that can stabilize the ionic species. It is often observed that "like dissolves like," where similar polarities tend to yield higher solubility rates. In summary, the solubility characteristics of 2-isopropyl-2-(1-naphthyl)-5-piperidin-1-ium-1-yl-pentanoic acid;chloride are tailored by its structural components and the surrounding environment.

Interesting facts

Interesting Facts about 2-isopropyl-2-(1-naphthyl)-5-piperidin-1-ium-1-yl-pentanoic acid;chloride

This compound, often recognized for its complex structure and potential applications, showcases the fascinating interplay between organic chemistry and pharmacology.

Key Features

  • Dual Functional Groups: The presence of both piperidine and carboxylic acid moieties suggests interesting reactivity and interaction capabilities, making it a candidate for various synthetic pathways.
  • Naphthalene Derivative: As a substituent, the 1-naphthyl group contributes significantly to the compound's chemical behavior and biological activity, thanks to its aromatic characteristics.
  • Ionizable Nature: The compound is a salt due to the chloride, indicating it can facilitate ionic interactions, which are essential in biological systems and drug interactions.

Applications and Research

The complex nature of this compound often leads to interest in its applications in medicinal chemistry, including:

  • Potential development as a pharmacological agent targeting central nervous system disorders.
  • Exploration as a chemical probe for studying neurotransmitter systems due to its piperidine structure.
  • Formation of complexes with biomolecules, which can lead to innovative drug delivery systems.

Quote from Research

As emphasized in recent studies, "Understanding the multifaceted interactions of molecules like 2-isopropyl-2-(1-naphthyl)-5-piperidin-1-ium-1-yl-pentanoic acid can unlock new pathways in therapeutic development." This statement highlights the importance of detailed exploration of compounds in pharmaceutical research.

In conclusion, the intriguing structure and reactivity of 2-isopropyl-2-(1-naphthyl)-5-piperidin-1-ium-1-yl-pentanoic acid;chloride make it a significant subject of study, with potential applications that could impact various fields, especially in the realm of drug discovery and development.

Synonyms
1-Naphthaleneacetic acid, alpha-isopropyl-alpha-(3-piperidinopropyl)-, hydrochloride
6525-13-9
alpha-Isopropyl-alpha-(3-piperidinopropyl)-1-naphthaleneacetic acid hydrochloride