Menthol | Solubility of Things

Identification

Molecular formula

C₁₀H₂₀O

CAS number

1490-04-6

IUPAC name

2-isopropyl-5-methyl-cyclohexanol

State

Menthol exists as a solid at room temperature and is typically available in the form of crystals or as a racemic mixture.

Melting point (Celsius)

42.00

Melting point (Kelvin)

315.00

Boiling point (Celsius)

212.00

Boiling point (Kelvin)

485.00

General information

Molecular weight

156.27g/mol

Molar mass

156.2700g/mol

Density

0.8909g/cm³

Appearence

Menthol appears as a waxy, crystalline substance, clear or white in color. It is solid at room temperature and typically has a minty, cooling odor.

Comment on solubility

Solubility of 2-isopropyl-5-methyl-cyclohexanol

2-isopropyl-5-methyl-cyclohexanol, with the chemical formula C₁₀H₂₀O, exhibits unique solubility characteristics that merit attention. Understanding its solubility is crucial for applications in various fields, including organic chemistry, pharmaceuticals, and industrial formulations.

Key Points on Solubility:

Polar Nature: The presence of the hydroxyl group (-OH) in 2-isopropyl-5-methyl-cyclohexanol indicates that this compound has polar characteristics, which generally enhances solubility in polar solvents such as water.
Hydrophobic Portion: Conversely, the cyclohexanol structure and isopropyl groups contribute to hydrophobicity, suggesting that this compound may have limited solubility in water.
Solvent Compatibility: This compound is likely to be more soluble in organic solvents such as ethanol, methanol, or diethyl ether, due to similar non-polar characteristics.
Temperature Influence: Like many organic compounds, solubility can be affected by temperature; higher temperatures often increase solubility in organic solvents.

In summary, while 2-isopropyl-5-methyl-cyclohexanol may show limited solubility in water due to hydrophobic influences, its soluble behavior in organic solvents highlights its versatility in chemical applications. The dual nature of this compound emphasizes the importance of solvent choice in practical uses and researches.

Interesting facts

Interesting Facts about 2-Isopropyl-5-methyl-cyclohexanol

2-Isopropyl-5-methyl-cyclohexanol is a fascinating compound belonging to the class of alcohols and presents several intriguing features worth noting:

Versatile Applications: This compound is noteworthy for its use in various industries, including the fragrance and flavor industry, where it can contribute to unique scent profiles.
Cyclic Structure: The cyclohexanol framework offers unique steric and electronic properties, making it a subject of interest in organic synthesis and pharmaceuticals.
Chirality: The presence of chiral centers in the molecule allows for the existence of different enantiomers. This characteristic can lead to different biological activities, which is significant in drug development.
Research Interest: Due to its structural similarities to more common cyclic alcohols, this compound attracts attention in the study of reaction mechanisms and molecular interactions.
Natural Occurrence: 2-Isopropyl-5-methyl-cyclohexanol may be found in trace amounts in certain essential oils, highlighting its potential as a natural product.

In summary, 2-isopropyl-5-methyl-cyclohexanol is not merely a chemical entity; it embodies a multitude of applications and scientific inquiries. Its complex structure provides a rich avenue for exploration in both academic and industrial settings. As one scientist is quoted, "The beauty of organic chemistry lies in the diverse functionalities of seemingly simple compounds."

Synonyms

MENTHOL

dl-Menthol

1490-04-6

2-Isopropyl-5-methylcyclohexanol

15356-70-4

89-78-1

Cyclohexanol, 5-methyl-2-(1-methylethyl)-

Menthyl alcohol

p-Menthan-3-ol

Mentholum

Caswell No. 540

Mineral ice

5-methyl-2-propan-2-ylcyclohexan-1-ol

(+/-)-Menthol

Hexahydrothymol

3-Hydroxy-p-menthane

CCRIS 9231

EINECS 216-074-4

Neomenthol

Menthol [USP]

Menthol natural

EPA Pesticide Chemical Code 051601

rac-Menthol

HSDB 593

DTXSID8029650

AI3-08161

Therapeutic mineral ice

Menthol, dl-

5-Methyl-2-(1-methylethyl)cyclohexanol

2-Isopropyl-5-methylcyclohexan-1-ol

MFCD00001484

Fisherman's friend lozenges

Racementol

DTXCID30805

CHEBI:25187

(1R,2S,5R)-Menthol

EC 216-074-4

Menthol (USP)

(1S, 2S, 5R)-(+)-Neomenthol

491-01-0

5-methyl-2-(propan-2-yl)cyclohexanol

DL-ISOMENTHOL

Menthol 1000 microg/mL in Acetonitrile

5-methyl-2-(propan-2-yl)cyclohexan-1-ol

(+/-)-Menthol, racemic

(1R,2R,5R)-Isomenthol

Racemic menthol

FEMA No. 2665

491-02-1

3-p-Menthanol

Menthol, cis-1,3,trans-1,4-

MEGGEZONE

MFCD00062983

Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1S-(1.alpha.,2.alpha.,5.beta.)]-

3-p-Menthol

(+/-)-p-Menthan-3-ol

CAS-1490-04-6

L(-)-Menthol

Robitussin Cough Drops

UNII-L7T10EIP3A

(1R,2R,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol

5-Methyl-2-(1-methylethyl)-cyclohexanol

Menthol racemate

MFCD00062980

Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1.alpha.,2.beta.,5.alpha.)-

(-)menthol

NCGC00159382-02

(-) menthol

Menthol (Standard)

4-Isopropyl-1-methylcyclohexan-3-ol

BOHENAO

Menthol, 99%

dextro,laevo-neomenthol

dl-Menthol (JP17)

1-methyl-4-isopropyl-3-hydroxycyclohexane

Emtricitabine Impurity 9

MENTHOL (II)

MENTHOL (MART.)

MENTHOL, UNSPECIFIED

SCHEMBL4612

L7T10EIP3A

Menthol, (.+/-.)-

Menthol, puriss., 99.0%

CHEMBL256087

DL-Menthol, analytical standard

MENTHOL (USP MONOGRAPH)

HY-N1369R

LEVOMENTHOL OR RACEMENTHOL

MENTHOL, UNSPECIFIED FORM

SALONPAS COMPONENT MENTHOL

Fisherman's friend lozenges (TN)

BDBM248162

HMS3744K19

2-Isopropyl-5-methylcyclohexanol #

BCP27552

BCP31841

CS-M3737

HY-N1369

menthol crystals; 15356-70-4

QAA35670

MENTHOL COMPONENT OF SALONPAS

Tox21_200010

Tox21_303464

1-Methyl-4-isopropyl-3-cyclohexanol

BBL009325

DL-Menthol, >=95%, FCC, FG

STK802468

AKOS000119740

AKOS016843634

Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1.alpha.,2.alpha.,5.beta.)-

SB35230

SB44308

SB44857

Menthol, SAJ special grade, >=98.0%

NCGC00159382-03

NCGC00159382-04

NCGC00159382-05

NCGC00159382-06

NCGC00257403-01

NCGC00257564-01

1ST40117

FM178382

HY-75161

IE182323

IN182314

SY004225

SY010603

SY073200

SY157908

VS-02042

DB-063989

Levomenthol; D-(-)-Menthol; (-)-Menthol

CS-0016777

M0321

NS00001027

EN300-19914

LEVOROTATORY-MENTHOL OR RACEMIC-MENTHOL

(+/-)-Menthol, racemic, >=98.0% (GC)

2-Isopropy-5-methylcyclohexanol-1,2,6,6-d4

D04849

D04918

E80543

BRD-A54393207-001-03-6

Q27109870

L-p-Menthan-3-ol; Menthol ,natural; (1R,2S,5R)-(-)-Menthol

Menthol-plus it inverted exclamation markas 3 isomers-1,2,6,6-d4

Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1.alpha.,2.beta.,5.alpha.)-(.+/-.)-

Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1R-(1.alpha.,2.alpha.,5.beta.)]-

L-Menthol; (-)-Menthol; Levomenthol; Menthomenthol;2-isopropyl-5-methyl-cyclohexanol;Menthol