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Menthol salicylate

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Identification
Molecular formula
C16H22O2
CAS number
89-78-1
IUPAC name
(2-isopropyl-5-methyl-cyclohexyl) 2-aminobenzoate
State
State

At room temperature, menthol salicylate is generally in a liquid state, although it can become a crystalline solid if stored in cooler conditions.

Melting point (Celsius)
15.00
Melting point (Kelvin)
288.15
Boiling point (Celsius)
318.30
Boiling point (Kelvin)
591.45
General information
Molecular weight
235.32g/mol
Molar mass
235.3160g/mol
Density
1.0200g/cm3
Appearence

Menthol salicylate typically appears as a colorless to faintly yellow liquid. It might have a characteristic aromatic odor which is often described as pleasant or minty due to the menthol component. The compound may solidify at lower temperatures, becoming a crystalline solid.

Comment on solubility

Solubility of (2-isopropyl-5-methyl-cyclohexyl) 2-aminobenzoate

The solubility of (2-isopropyl-5-methyl-cyclohexyl) 2-aminobenzoate can be influenced by various factors, and it’s essential to consider the following:

  • Polarity: This compound has both hydrophobic (nonpolar) cyclohexyl groups and polar amine and carboxylate functional groups. This dual nature can lead to varying solubility in different solvents.
  • Solvent Type:
    • Water: Due to its hydrophobic characteristics, it is expected to have low solubility in water.
    • Organic Solvents: It's likely to be more soluble in organic solvents such as alcohols or ethers due to its nonpolar character.
  • Temperature Effect: Generally, solubility can increase with temperature; therefore, heating the solvent may enhance solubility for this compound.

In summary, the solubility of (2-isopropyl-5-methyl-cyclohexyl) 2-aminobenzoate is complex and heavily dependent on both solvent choice and environmental conditions. It serves as a reminder that understanding the chemical nature of compounds is crucial for predicting their solubility behaviors in various environments.

Interesting facts

Interesting Facts about (2-isopropyl-5-methyl-cyclohexyl) 2-aminobenzoate

(2-isopropyl-5-methyl-cyclohexyl) 2-aminobenzoate is an intriguing compound that showcases the diversity of organic chemistry. Its structure provides a platform for numerous applications and interesting chemical behavior. Here are some fascinating insights into this compound:

  • Structural Complexity: The compound features a cyclohexane ring, which is a saturated hydrocarbon structure, that plays a critical role in the rigidity and reactivity of the molecule. The addition of an isopropyl group and a methyl group enhances its steric bulk, leading to unique interactions with other molecules.
  • Biological Activity: Compounds similar to this one often exhibit a range of biological activities. The presence of the 2-aminobenzoate moiety suggests potential pharmaceutical applications. Many amino benzoates are known to act as enzyme inhibitors or could demonstrate anti-inflammatory properties.
  • Illustration of Substitution Patterns: This compound is a great example of substitution in organic molecules. The varied arrangements of substituent groups can impact the compound's chemical behavior, showing how slight modifications can lead to vast changes in properties and activities.
  • Applications in Material Science: The structural features of (2-isopropyl-5-methyl-cyclohexyl) 2-aminobenzoate could result in useful properties for material science. It can potentially act as an additive or precursor in the synthesis of polymers, enhancing their performance as adhesives or coatings.
  • Synthesis Pathway: Understanding the synthesis of this compound involves exploring multiple reaction pathways, illustrating how various organic transformations can lead to complex molecules. This is a prime example of the creativity inherent in synthetic organic chemistry.

In summary, (2-isopropyl-5-methyl-cyclohexyl) 2-aminobenzoate is a compound that not only exemplifies complexities in structure and function but also opens doors for further research and application in various fields. As the famous chemist Linus Pauling once said, “The best way to have a good idea is to have a lot of ideas.” This inclusion of a multifaceted compound into the chemical landscape certainly encourages innovative thoughts and further investigations.

Synonyms
MENTHYL ANTHRANILATE
Meradimate
134-09-8
Meradimate [INN]
Menthyl-O-aminobenzoate
(5-methyl-2-propan-2-ylcyclohexyl) 2-aminobenzoate
Anthranilic acid, p-menth-3-yl ester
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 2-aminobenzoate
J9QGD60OUZ
5-methyl-2-(propan-2-yl)cyclohexyl 2-aminobenzoate
DTXSID3047895
2-isopropyl-5-methylcyclohexyl 2-aminobenzoate
Cyclohexanol,5-methyl-2-(1-methylethyl)-, 1-(2-aminobenzoate)
NCGC00159361-02
DTXCID3027871
CAS-134-09-8
CCRIS 2468
Menthyl o-aminobenzoate
EINECS 205-129-8
UNII-J9QGD60OUZ
Meradimato
Meradimate [USAN:USP:INN]
Neo heliopan MA
Meradimate (USP/INN)
MERADIMATE [USAN]
Menthyl anthranilate, 98%
MERADIMATE [MART.]
MERADIMATE [USP-RS]
MERADIMATE [WHO-DD]
SCHEMBL18884
5-Methyl-2-(1-methylethyl)cyclohexanol-2-aminobenzoate
CHEMBL1597075
MENTHYL ANTHRANILATE [MI]
CHEBI:135974
MERADIMATE [USP MONOGRAPH]
Tox21_111602
Tox21_200561
BBL028008
STK083062
AKOS001387784
AKOS017278349
DB11096
Menthyl anthranilate, analytical standard
NCGC00159361-06
NCGC00258115-01
VS-08642
DB-042217
NS00008634
D04927
2-aminobenzoic acid (2-isopropyl-5-methyl-cyclohexyl) ester
Meradimate, United States Pharmacopeia (USP) Reference Standard
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, 1-(2-aminobenzoate)
Menthyl anthranilate, Pharmaceutical Secondary Standard; Certified Reference Material