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Norephedrine

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Identification
Molecular formula
C9H13NO
CAS number
700-12-9
IUPAC name
2-(isopropylamino)-1-phenyl-ethanol
State
State

At room temperature, Norephedrine is typically a solid. It has the form of white crystalline or powdery solid.

Melting point (Celsius)
133.00
Melting point (Kelvin)
406.15
Boiling point (Celsius)
219.00
Boiling point (Kelvin)
492.15
General information
Molecular weight
151.21g/mol
Molar mass
151.2070g/mol
Density
1.0950g/cm3
Appearence

Norephedrine is typically found as a white crystalline solid. It may also appear as colorless crystals depending on its purity and form of synthesis. The compound has a slightly bitter taste.

Comment on solubility

Solubility of 2-(isopropylamino)-1-phenyl-ethanol

2-(isopropylamino)-1-phenyl-ethanol, with its complex structure, presents intriguing solubility characteristics. Understanding its solubility is essential for applications in pharmaceuticals, chemistry, and various industrial processes. Here are some key points regarding its solubility:

  • Polar vs. Non-Polar Solvent: This compound is generally considered to be more soluble in polar solvents due to the presence of an amino group (-NH), which can form hydrogen bonds with water and other polar solvents.
  • Solubility in Water: Although there may be a degree of solubility in water, it is typically limited because of its hydrophobic phenyl group.
  • Effect of pH: The solubility can vary with pH; under more acidic conditions, the amino group can become protonated, potentially increasing solubility in aqueous solutions.
  • Common Organic Solvents: 2-(isopropylamino)-1-phenyl-ethanol is often found to be soluble in common organic solvents such as ethanol and methanol, making it versatile for laboratory use.

To recap, while 2-(isopropylamino)-1-phenyl-ethanol shows some degree of solubility in water, it is primarily soluble in polar organic solvents, highlighting the importance of solvent choice in its applications. As stated, "the solubility of compounds is a defining feature that impacts their functionality and behavior in various environments."

Interesting facts

Interesting Facts about 2-(Isopropylamino)-1-phenyl-ethanol

2-(Isopropylamino)-1-phenyl-ethanol, often referred to in research contexts for its intriguing properties and potential applications, is a compound that stands out in the realm of chemical science. Here are some fascinating insights:

  • Biological Importance: This compound has been of interest in pharmacology due to its structural resemblance to various drugs, potentially influencing biological systems.
  • Chirality: The molecule can exhibit chirality, meaning it may have two mirror-image forms (enantiomers), which can result in different biological responses. This is a crucial concept in medicinal chemistry, as often one enantiomer is therapeutically active while the other may not be.
  • Synthetic Routes: Scientists have explored multiple synthetic pathways to create this compound, including the use of asymmetric synthesis, which highlights its complexity and the ingenuity of chemists at work.
  • Applications in Research: 2-(Isopropylamino)-1-phenyl-ethanol serves as a valuable intermediate in the synthesis of other organic compounds, demonstrating its utility in various chemical reactions.
  • Potential Side Effects: When considering its pharmacological potential, research into side effects and toxicity is essential, illustrating the balance required in drug development.

Overall, the exploration of 2-(isopropylamino)-1-phenyl-ethanol opens up discussions about the interplay between molecular structure and biological function, offering insights that could pave the way for new therapies and research methodologies.

Synonyms
4164-21-0
1-Phenyl-2-isopropylaminoethanol
KK 1-2
NSC 23624
alpha-(Isopropylaminomethyl)benzyl alcohol
1-Phenyl-1-oxy-2-(isopropylamino)-aethan [German]
alpha-(((1-Methylethyl)amino)methyl)benzenemethanol
Benzenemethanol, alpha-(((1-methylethyl)amino)methyl)-
1-Phenyl-1-oxy-2-(isopropylamino)-aethan
BENZYL ALCOHOL, alpha-(ISOPROPYLAMINOMETHYL)-
alpha-[[(1-Methylethyl)amino]methyl]benzenemethanol
Benzenemethanol, alpha-(((1-methylethyl)amino)methyl)-(9CI)
2-(isopropylamino)-1-phenylethanol
1-phenyl-2-(propan-2-ylamino)ethanol
2-ISOPROPYLAMINO-1-PHENYLETHANOL
1-Phenyl-2-[(propan-2-yl)amino]ethan-1-ol
NSC23624
METAPROTERENOL_met022
CHEMBL31727
SCHEMBL4564683
YANYGOBZUASRHR-UHFFFAOYSA-N
DTXSID801243902
EAA16421
2-isopropylamino-1-phenyl-1-ethanol
MFCD01732724
NSC-23624
AKOS009068500
CS-0260385
G22038
EN300-7505698
I+/--[[(1-Methylethyl)amino]methyl]benzenemethanol