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2-Isopropylaniline

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Identification
Molecular formula
C9H13N
CAS number
5338-48-3
IUPAC name
2-isopropylaniline
State
State

The compound is in a liquid state at room temperature.

Melting point (Celsius)
-33.00
Melting point (Kelvin)
240.15
Boiling point (Celsius)
212.00
Boiling point (Kelvin)
485.15
General information
Molecular weight
135.21g/mol
Molar mass
135.2070g/mol
Density
0.9602g/cm3
Appearence

2-Isopropylaniline is a colorless to yellow liquid. Its appearance can vary based on purity, with impurities sometimes causing a yellow tint.

Comment on solubility

Solubility of 2-Isopropylaniline

2-Isopropylaniline, also known as N-(propan-2-yl)aniline, exhibits intriguing solubility characteristics that are important to consider when utilizing this compound in various applications.

  • Solvent Compatibility: 2-Isopropylaniline is primarily soluble in organic solvents such as:
    • Chloroform
    • Benzene
    • Ethyl acetate
    • Ethanol
  • Water Solubility: Its solubility in water is notably low, generally categorized as:
    • Poor solubility due to its hydrophobic isopropyl group
    • Limited interactions with water molecules

This varied solubility profile underscores the importance of choosing appropriate solvents when working with 2-isopropylaniline in synthetic processes, highlighting the need for specific conditions to enhance its solubility for desired reactions.

As noted, "the solubility of a compound can significantly influence its reactivity and bioavailability," emphasizing the critical role of understanding these properties in chemical science.

Interesting facts

Interesting Facts about 2-Isopropylaniline

2-Isopropylaniline, also known as N-(propan-2-yl)aniline, is an intriguing organic compound that falls within the category of aromatic amines. Here are some notable aspects of this compound that may interest both scientists and chemistry students:

  • Structure and Functionality: This compound features a unique configuration where an isopropyl group is substituted at the 2 position of the aniline ring. This specific substitution can influence the compound's reactivity and physical properties, making it an essential topic for those studying organic chemistry.
  • Applications: 2-Isopropylaniline is not only of academic interest but also has practical applications in various industries. It is often used as an intermediate in the synthesis of dyes, pesticides, and pharmaceuticals, illustrating the vital role of aniline derivatives in industrial chemistry.
  • Safety and Handling: As with many amines, safety precautions are necessary when working with 2-isopropylaniline. It is classified as a potential skin and eye irritant, so personal protective equipment (PPE) such as gloves and goggles should be utilized in laboratory settings.
  • Reactivity: The presence of the amine group (-NH2) in combination with the aromatic ring leads to interesting reactivity, particularly with electrophilic aromatic substitution. This characteristic makes it a valuable compound for exploring reaction mechanisms.
  • Research Applications: Ongoing research is focused on the effectiveness of 2-isopropylaniline in various chemical reactions, including its potential role in the development of novel materials and therapeutic agents.

Overall, 2-isopropylaniline stands as a significant compound in the realm of organic chemistry, providing rich avenues for exploration and understanding. As you delve into the world of chemical compounds, remember that each one carries its unique story and potential!

Synonyms
2-ISOPROPYLANILINE
643-28-7
o-Isopropylaniline
o-Cumidine
Benzenamine, 2-(1-methylethyl)-
o-Aminoisopropylbenzene
Aniline, o-isopropyl-
2-Isopropyl aniline
2-Aminoisopropylbenzene
2-(1-Methylethyl)benzenamine
BN8UZ4TE5F
EINECS 211-397-7
BRN 0636283
DTXSID6052328
DTXCID0030900
4-12-00-02630 (Beilstein Handbook Reference)
211-397-7
2-propan-2-ylaniline
2-(Propan-2-Yl)Aniline
o-Aminocumene
2-Aminocumene
MFCD00007720
2-Isopropylanine
2-isopropyaniline
2-i-propylaniline
2-isopropyl-aniline
2-iso-propyl aniline
2-isopropyl-phenylamine
aniline, 2-isopropyl-
UNII-BN8UZ4TE5F
2-[prop-2-yl]-aniline
2-(1-Methylethyl)aniline
2-Isopropylaniline, 97%
1-Amino-2-isopropylbenzene
SCHEMBL104513
CHEMBL3560385
[2-(1-methylethyl)phenyl]amine
YKOLZVXSPGIIBJ-UHFFFAOYSA-
CHEBI:183339
AAA64328
Tox21_303899
AC9367
STL164362
AKOS000119737
CS-W013349
PS-4565
SB75377
NCGC00357153-01
CAS-643-28-7
SY006015
DB-054644
I0318
NS00035669
EN300-19829
F2190-0521
Z104475672
InChI=1/C9H13N/c1-7(2)8-5-3-4-6-9(8)10/h3-7H,10H2,1-2H3