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2-(m-Tolyl)acetic acid

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Identification
Molecular formula
C9H10O2
CAS number
37502-52-0
IUPAC name
2-(m-tolyl)acetic acid
State
State

At room temperature, 2-(m-Tolyl)acetic acid is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
106.00
Melting point (Kelvin)
379.15
Boiling point (Celsius)
282.00
Boiling point (Kelvin)
555.15
General information
Molecular weight
150.18g/mol
Molar mass
150.1770g/mol
Density
1.0820g/cm3
Appearence

2-(m-Tolyl)acetic acid appears as a white to off-white crystalline solid. It is typically supplied in powder form.

Comment on solubility

Solubility of 2-(m-tolyl)acetic acid

2-(m-tolyl)acetic acid, with the chemical formula C10H12O2, is a fascinating compound when it comes to solubility. This particular carboxylic acid exhibits characteristics that can influence its behavior in different solvents. Here are some key points to consider:

  • Polar Solvents: Generally, 2-(m-tolyl)acetic acid tends to be more soluble in polar solvents such as water and alcohols due to the presence of the carboxylic acid functional group, which can form hydrogen bonds.
  • Non-Polar Solvents: In contrast, its solubility in non-polar solvents is lower. This is largely attributed to the hydrophobic characteristics of the m-tolyl group, which impedes interaction with non-polar environments.
  • Temperature Dependency: Solubility can also be temperature-dependent; typically, increasing the temperature may enhance the solubility of 2-(m-tolyl)acetic acid in both polar and non-polar solvents.

In summary, 2-(m-tolyl)acetic acid demonstrates varying solubility based on the solvent type and temperature conditions. As a rule of thumb, one might consider that:

"Like dissolves like"

This adage is quite applicable here, whereby the compound's solute-solvent interactions significantly determine its solubility profile.

Interesting facts

Interesting Facts about 2-(m-Tolyl)acetic Acid

2-(m-Tolyl)acetic acid, also known as m-toluic acid, is an intriguing compound that falls under the category of aromatic carboxylic acids. Here are some captivating aspects of this compound:

  • Structural Composition: The compound features a unique structure where a m-tolyl group is attached to an acetic acid moiety, resulting in interesting chemical reactivity due to the aromatic character.
  • Synthesis: 2-(m-Tolyl)acetic acid can be synthesized through various methods, including the reaction of m-xylene derivatives with chloroacetic acid or through oxidation processes, illustrating the versatility of synthetic organic chemistry.
  • Biological Relevance: Compounds like 2-(m-tolyl)acetic acid are studied for their potential biological activities, including anti-inflammatory and analgesic properties. The carboxylic acid functional group can play a crucial role in medicinal chemistry.
  • Applications: This compound has applications as a building block in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and other specialized chemical products.
  • Environmental Impact: The study of such compounds helps in understanding their behavior in the environment, which is important for assessing their ecological footprint and how they can be managed in industrial processes.

As a student or scientist working with 2-(m-tolyl)acetic acid, one may find that exploring its properties and reactions opens up a window to the fascinating world of aromatic chemistry and its applications in various fields. Always remember, the quote "Chemistry is the skeleton of science, and organic chemistry is its heart." perfectly captures the essence of how foundational compounds like 2-(m-tolyl)acetic acid contribute to broader scientific discovery.

Synonyms
3-Methylphenylacetic acid
m-Tolylacetic acid
2-(m-Tolyl)acetic acid
2-(3-methylphenyl)acetic acid
Benzeneacetic acid, 3-methyl-
(3-Methylphenyl)acetic acid
3-Methylbenzeneacetic acid
AF4FNN5J9F
EINECS 210-683-9
NSC-76090
CHEBI:88356
GJMPSRSMBJLKKB-UHFFFAOYSA-
DTXSID30211147
NSC 76090
DTXCID30133638
210-683-9
inchi=1/c9h10o2/c1-7-3-2-4-8(5-7)6-9(10)11/h2-5h,6h2,1h3,(h,10,11)
621-36-3
3-tolylacetic acid
m-Methylphenylacetic acid
MFCD00004340
methyll 3-methylphenylacetate
2-(m-Tolyl)aceticacid
3-Tolylacetate
m-tolyl acetic acid
m-Methylphenylacetate
m-Tolyl-acetic acid
2-m-tolylacetic acid
2-m-tolyl acetic acid
(3-Methylphenyl)acetate
UNII-AF4FNN5J9F
m-Tolylacetic acid, 99%
META-TOLYLACETIC ACID
SCHEMBL504093
ghl.PD_Mitscher_leg0.1056
CHEMBL136369
AAA62136
NSC76090
STR06561
STL166136
AKOS000154311
HY-W053507
PS-5142
AC-17035
SY048780
DB-027265
CS-0046111
NS00034931
T0880
EN300-62618
A10247
Q27160204
2-(3-Methylphenyl)acetic acid;M-methylphenylacetic acid;
F2191-0088