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N-(3-Methylphenyl)phthalamic acid

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Identification
Molecular formula
C15H13NO3
CAS number
27415-26-5
IUPAC name
2-(m-tolylcarbamoyl)benzoic acid
State
State
N-(3-Methylphenyl)phthalamic acid is a solid at room temperature, which is typical for many organic compounds structured as substituted benzoic acids. It maintains its solid state integrity under normal ambient conditions.
Melting point (Celsius)
219.00
Melting point (Kelvin)
492.15
Boiling point (Celsius)
265.00
Boiling point (Kelvin)
538.15
General information
Molecular weight
241.26g/mol
Molar mass
241.2620g/mol
Density
1.2970g/cm3
Appearence

N-(3-Methylphenyl)phthalamic acid is typically a white to off-white crystalline solid. The appearance can vary slightly based on impurities and the method of synthesis, but its pure form is characterized by fine crystals.

Comment on solubility

Solubility of 2-(m-tolylcarbamoyl)benzoic acid

The solubility of 2-(m-tolylcarbamoyl)benzoic acid can be influenced by several factors, making it an intriguing subject of study. Generally, this compound is slightly soluble in water, exhibiting a greater affinity for organic solvents. Here are some key points regarding its solubility:

  • Solvent Type: It is commonly more soluble in polar organic solvents such as ethanol and acetone.
  • Temperature Dependence: Like many organic acids, increased temperature may enhance its solubility in these solvents.
  • pH Impact: The ionization of the carboxylic acid group can significantly affect solubility; at higher pH levels, the compound may become more soluble due to deprotonation.

As with many aromatic compounds, the presence of bulky groups like the m-tolyl carbamoyl substituent can hinder solubility. To summarize, it is essential to consider both the chemical structure and environmental conditions when discussing the solubility of 2-(m-tolylcarbamoyl)benzoic acid, as they play a crucial role in its behavior in various solvents.

Interesting facts

Interesting Facts about 2-(m-tolylcarbamoyl)benzoic acid

2-(m-tolylcarbamoyl)benzoic acid, often referred to simply as a derivative of benzoic acid, belongs to a class of compounds that have fascinated chemists for various reasons. Here are some interesting insights into this compound:

  • Pharmaceutical Relevance: Compounds like 2-(m-tolylcarbamoyl)benzoic acid have potential uses in the pharmaceutical industry due to their ability to act as intermediates in drug synthesis.
  • Functional Groups: This compound showcases the significance of functional groups. The presence of both a carboxylic acid and an amide group allows for a variety of reactions, enhancing its versatility in synthetic pathways.
  • Chemical Reactivity: The structure of 2-(m-tolylcarbamoyl)benzoic acid gives it unique chemical properties. It can participate in reactions such as nucleophilic substitution and acylation, which are fundamental in organic synthesis.
  • Biological Activity: Researchers are studying its potential biological activities, as related compounds have been linked to various therapeutic effects. This opens doors for further exploration in medicinal chemistry.

In the words of famous chemist Marie Curie, "Nothing in life is to be feared, it is only to be understood." This compound exemplifies the importance of understanding chemical structures and their implications in both science and industry.

As research progresses, compounds like 2-(m-tolylcarbamoyl)benzoic acid could lead to breakthroughs in drug discovery, showcasing the never-ending allure of organic chemistry.

Synonyms
3'-Methylphthalanilic acid
N-m-Tolylphthalamic acid
85-72-3
Tomaset
DURASET
Phthalamate
Duraset 20W
2-(m-tolylcarbamoyl)benzoic acid
N-m-Tolylphthalaminic acid
Phthalanilic acid, 3'-methyl-
N-Metatolyl phthalamic acid
N-M-T
N-meta-Tolylphthalamic acid
Caswell No. 860
2-[(3-methylphenyl)carbamoyl]benzoic acid
Kyselina N-m-tolylftalamova
EINECS 201-626-9
EPA Pesticide Chemical Code 030901
NSC 522078
UNII-3R15BUY339
2-(((3-Methylphenyl)amino)carbonyl)benzoic acid
BRN 2698092
AI3-23601
3R15BUY339
NSC-522078
Benzoic acid, 2-[[(3-methylphenyl)amino]carbonyl]-
DTXSID0041486
0-12-00-00862 (Beilstein Handbook Reference)
Benzoic acid, 2-(((3-methylphenyl)amino)carbonyl)-
MFCD00020274
3'-METHYLPHTHALANILIC ACID [MI]
2-[[(3-methylphenyl)amino]carbonyl]benzoic acid
2-{[(3-methylphenyl)amino]carbonyl}benzoic acid
Kyselina N-m-tolylftalamova [Czech]
2-(3-Methylphenylcarbamoyl)benzoic acid
WLN: QVR BVMR C
Oprea1_465165
MLS000058802
SCHEMBL3356211
CHEMBL1588580
DTXCID8021486
HMS1578M16
HMS2414E11
NSC522078
AKOS001381771
2-(3-Toluidinocarbonyl)benzoic acid #
SDCCGMLS-0038971.P002
SMR000069068
DB-244676
CS-0281035
EU-0000539
NS00039056
AB00390459-09
SR-01000392380
SR-01000392380-1
Q27257922
Z57434612