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Naphazoline

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Identification
Molecular formula
C14H14N2
CAS number
835-31-4
IUPAC name
2-(m-tolylmethyl)-4,5-dihydro-1H-imidazole
State
State

At room temperature, naphazoline exists as a solid.

Melting point (Celsius)
219.00
Melting point (Kelvin)
492.15
Boiling point (Celsius)
353.80
Boiling point (Kelvin)
626.95
General information
Molecular weight
228.32g/mol
Molar mass
228.3220g/mol
Density
1.0986g/cm3
Appearence

Naphazoline typically appears as a white to pale brown crystalline powder.

Comment on solubility

Solubility of 2-(m-tolylmethyl)-4,5-dihydro-1H-imidazole

The solubility of 2-(m-tolylmethyl)-4,5-dihydro-1H-imidazole can be characterized by several key factors. Understanding its solubility is essential for various applications in both research and industry.

Factors Influencing Solubility

  • Polarity: The compound has both hydrophobic (due to the m-tolyl group) and polar regions (due to the imidazole ring), which can impact its solubility in different solvents.
  • Temperature: Solubility often increases with temperature; thus, this compound may show varying solubility under different temperature conditions.
  • Solvent Choice: It is expected to be soluble in organic solvents like ethanol and dimethyl sulfoxide (DMSO), but may have limited solubility in water.

Generally, for a compound of this structure, one might anticipate moderate solubility in organic solvents due to the presence of aromatic functional groups, while its solubility in polar solvents may be restricted.

Quote on Solubility

As the saying goes, “Like dissolves like.” This principle underlines the importance of matching the solvent's polarity with that of the solute for optimal solubility.

In conclusion, while specific solubility data for 2-(m-tolylmethyl)-4,5-dihydro-1H-imidazole could vary, its dual nature suggests a more favorable interaction with organic rather than aqueous environments.

Interesting facts

Interesting Facts about 2-(m-tolylmethyl)-4,5-dihydro-1H-imidazole

2-(m-tolylmethyl)-4,5-dihydro-1H-imidazole is a fascinating compound belonging to the class of imidazoles, which are known for their diverse biological and chemical properties. This compound is particularly noteworthy for the following reasons:

  • Biological Relevance: Imidazole derivatives often exhibit significant biological activity, including antimicrobial, antifungal, and antitumor properties. This makes 2-(m-tolylmethyl)-4,5-dihydro-1H-imidazole a potential candidate for pharmaceutical research.
  • Structural Diversity: The unique structure of this compound, featuring a tolyl group attached to the imidazole ring, can influence its chemical reactivity and interaction with biological targets. Such structural variations are crucial in the development of new drugs.
  • Applications in Organic Synthesis: Imidazole derivatives are frequently used as building blocks in organic synthesis. The presence of the m-tolylmethyl group can enhance the compound's ability to participate in various chemical reactions, making it a valuable precursor in synthetic chemistry.
  • Catalytic Properties: Some imidazole derivatives serve as catalysts in organic reactions. Research into the catalytic activity of 2-(m-tolylmethyl)-4,5-dihydro-1H-imidazole could reveal new pathways for efficient synthesis.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." Exploring the properties and potential applications of compounds like 2-(m-tolylmethyl)-4,5-dihydro-1H-imidazole fosters innovation in the field of chemistry through creativity and experimentation.

This compound serves as a reminder of the intricate connections between chemistry and medicine, where small molecules can lead to significant advancements in human health and science.

Synonyms
2-(m-Methylbenzyl)-2-imidazoline
2-IMIDAZOLINE, 2-(m-METHYLBENZYL)-
BRN 0908911
5496-20-8
DTXSID70203485
DTXCID70125976
5-23-07-00012 (beilstein handbook reference)
SCHEMBL14340604