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Madaluzic acid

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Identification
Molecular formula
C15H14O3
CAS number
1078-60-8
IUPAC name
2-methoxy-2,2-diphenyl-acetic acid
State
State

At room temperature, 2-methoxy-2,2-diphenylacetic acid is typically found in a solid state. Its crystalline nature is typical of many organic acids, which tend to have high melting points due to strong intermolecular forces between their molecules.

Melting point (Celsius)
189.00
Melting point (Kelvin)
462.15
Boiling point (Celsius)
313.00
Boiling point (Kelvin)
586.15
General information
Molecular weight
258.29g/mol
Molar mass
258.2890g/mol
Density
0.8520g/cm3
Appearence

2-Methoxy-2,2-diphenylacetic acid appears as a colorless to pale-yellow crystalline solid. Its structure contains benzene rings, which can affect its optical properties and potentially give it a distinct appearance depending on concentration and form.

Comment on solubility

Solubility of 2-methoxy-2,2-diphenyl-acetic acid

The solubility of 2-methoxy-2,2-diphenyl-acetic acid (C16H16O3) is an interesting aspect of its chemical behavior. This compound is generally classified as having low solubility in water, which can be attributed to its large non-polar phenyl groups that hinder interaction with polar solvents like water.

However, its solubility can vary significantly depending on the solvent used. Here are some key points to consider:

  • Polar Solvents: Limited solubility due to hydrophobic character.
  • Non-Polar Solvents: Greater solubility, allowing for better interaction.
  • Temperature Influence: Solubility may increase with temperature, promoting molecular motion.

As a general rule, the dissolution of this compound is influenced by the following factors:

  1. Molecular Structure: The presence of bulky diphenyl groups limits interaction with water molecules.
  2. Hydrophobicity: The compound's hydrophobic portions escape interaction with polar solvents.
  3. Interactions: Hydrogen bonding may occur with specific polar solvents, but overall interactions remain weak.

In summary, while 2-methoxy-2,2-diphenyl-acetic acid exhibits low solubility in water, it can dissolve more readily in non-polar solvents. Understanding these solubility characteristics is pivotal for applications in pharmaceuticals and organic synthesis where solvent choice impacts reactivity and functionality.

Interesting facts

Interesting Facts about 2-Methoxy-2,2-diphenyl-acetic Acid

2-Methoxy-2,2-diphenyl-acetic acid is a fascinating compound with a unique structure and interesting properties that make it noteworthy in the field of organic chemistry. Here are some compelling facts about this intriguing substance:

  • Structure and Functionality: The compound features a methoxy group (–OCH3) attached to a diphenyl acetic acid backbone, which contributes to its pronounced chemical reactivity and versatility.
  • Biological Significance: This compound has been studied for its potential therapeutic applications, especially in the context of anti-inflammatory and analgesic activities. Researchers continue to investigate its effects on pain relief and other medicinal properties.
  • Synthetic Routes: The synthesis of 2-methoxy-2,2-diphenyl-acetic acid can involve various innovative organic reactions, showcasing techniques like aromatic substitutions and esterifications. This provides a practical learning opportunity for chemistry students to explore synthetic methodologies.
  • Application in Research: Due to its unique structure, this compound is often used in academic research to better understand substitution reactions and the phenomena of sterics and electronics in organic compounds.
  • Chirality and Isomerism: The chiral nature of this compound lends itself to the study of stereochemistry, enabling scientists to explore how different isomers can have vastly different biological activities.

In summary, 2-methoxy-2,2-diphenyl-acetic acid is not just another compound; it provides a rich context for understanding complex organic reactions and serves as a potential candidate in the development of pharmaceuticals. Further studies could unlock even more exciting functionalities of this compound!

Synonyms
DPMA acid
(diphenylmethoxy)acetate
RefChem:920414
(diphenylmethoxy)acetic acid
Diphenylmethoxyacetic acid
7475-61-8
2-methoxy-2,2-diphenyl-acetic acid
methoxy(diphenyl)acetic acid
2-methoxy-2,2-diphenylacetic acid
Acide diphenylmethoxyacetique [French]
BRN 2530513
UNII-5EX98UAT82
Oprea1_292492
SCHEMBL340836
methoxy (diphenyl acetic acid)
DTXSID60943969
YNDNIPMGZASSRG-UHFFFAOYSA-N
NSC400473
STK526412
AKOS000211898
NSC-400473
DS-004210
3-06-00-03370 (Beilstein Handbook Reference)
SR-01000260573
SR-01000260573-1