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Creosol

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Identification
Molecular formula
C8H10O2
CAS number
93-51-6
IUPAC name
2-methoxy-4-methyl-phenol
State
State

At room temperature, creosol is a liquid. While it is typically fluid at standard conditions, it can sometimes be encountered in a more viscous form in cooler environments.

Melting point (Celsius)
7.00
Melting point (Kelvin)
280.15
Boiling point (Celsius)
221.50
Boiling point (Kelvin)
494.65
General information
Molecular weight
152.20g/mol
Molar mass
152.1950g/mol
Density
1.0793g/cm3
Appearence

Creosol is an organic compound appearing as a colorless or pale yellow oily liquid. It may darken upon exposure to air and light over time. The liquid has a distinct smoky and phenolic odor characteristic of the complex mixture it is often derived from, such as wood tar or coal tar.

Comment on solubility

Solubility of 2-methoxy-4-methyl-phenol

2-methoxy-4-methyl-phenol, also known as p-cresol methyl ether, exhibits interesting solubility properties that are important for its practical applications. This compound is characterized by its moderately polar structure, which influences its interaction with various solvents.

Key Points on Solubility:

  • Solvent Interaction: It is generally soluble in organic solvents such as ethanol and ether, making it suitable for use in various organic reactions.
  • Water Solubility: 2-methoxy-4-methyl-phenol shows limited solubility in water. Its ability to dissolve in water is influenced by the presence of the methoxy group, which can engage in hydrogen bonding to some extent.
  • Effect of Temperature: Like many organic compounds, its solubility in solvents can increase with temperature, enhancing its usability in different chemical processes.

Overall, the solubility characteristics of 2-methoxy-4-methyl-phenol play a crucial role in its reactivity and efficacy as a chemical compound. The balance of its polar and non-polar attributes makes it versatile yet somewhat challenging in aqueous environments.

Interesting facts

Interesting Facts about 2-Methoxy-4-methyl-phenol

2-Methoxy-4-methyl-phenol, often known as Thymol, is a fascinating compound that garners interest in both the scientific and commercial realms. Here are some engaging insights:

  • Natural Antiseptic: Thymol is derived from thyme oil, and it is well-known for its antimicrobial properties. It has been shown to effectively combat various strains of bacteria, making it a valuable component in hand sanitizers and disinfectants.
  • Flavor and Aroma: The compound possesses a unique flavor and aroma, contributing to its use in food products as a flavoring agent. Its spicy, warm notes are highly appreciated in culinary applications.
  • Medicinal Use: Traditional medicine has utilized Thymol for centuries. It is reputed to support respiratory health, alleviating symptoms associated with cough and bronchitis, showcasing its potential therapeutic benefits.
  • Insect Repellent: Thymol's strong scent acts as a natural repellent against certain insects, proving beneficial in both agriculture and home use. It is less harmful compared to synthetic alternatives.
  • Research Interest: Current studies are exploring Thymol's potential role in combating antibiotic resistance, which is a growing concern in modern medicine. Its ability to disrupt bacterial cell membranes could lead to innovative treatments.

In summary, 2-Methoxy-4-methyl-phenol is not only important in various industries but also has significant implications for health, wellness, and environmental applications. As scientists, understanding the properties and potential of such compounds is essential for developing new, sustainable solutions.

Synonyms
2-METHOXY-4-METHYLPHENOL
93-51-6
Creosol
4-Methylguaiacol
Phenol, 2-methoxy-4-methyl-
2-Methoxy-p-cresol
4-Methyl guaiacol
p-Methylguaiacol
p-Creosol
Homoguaiacol
2-Methoxy-4-cresol
p-Cresol, 2-methoxy-
4-Hydroxy-3-methoxytoluene
4-Methyl-2-methoxyphenol
Kreosol
Rohkcrsol
2-methoxy-4-methyl-phenol
3-Methoxy-4-hydroxytoluene
Cresolum drudum
4-Hydroxy-3-methoxy-1-methylbenzene
Homocatechol monomethyl ether
Kreosol [German]
Valspice
1-Hydroxy-2-methoxy-4-methylbenzene
FEMA No. 2671
NSC 4969
MFCD00002378
UNII-W9GW1KZG6N
W9GW1KZG6N
2-Hydroxy-5-methylanisole
2-methoxy-4-methyl phenol
EINECS 202-252-9
Phenol, 4-methyl-2-methoxy
BRN 1862340
DTXSID6047105
AI3-15891
NSC-4969
CREOSOL [MI]
DTXCID4027105
CHEBI:89886
NSC4969
4-06-00-05878 (Beilstein Handbook Reference)
2-METHOXY-4-METHYLPHENOL [FHFI]
2-?Methoxy-?4-?methylphenol
2-2-Methoxy-4-methylphenol
P-Methylguaicol
4-Methylguiacol
Creosol (Standard)
Homocatechol methyl ester
2-Methoxy-4-methylphenol (Methyl guaiacol)
3-Methoxy-4-methyl-Phenol
SCHEMBL92236
2-METHOXY-P- CRESOL
CHEMBL3182715
2-Methoxy-4-methylphenol, 9CI
FEMA 2671
BCP19090
HY-W040971R
2-Methoxy-4-methylphenol (creosol)
Tox21_302681
2-Methoxy-4-methylphenol, >=98%
AKOS000120520
CS-W021711
FM36438
HY-W040971
CAS-93-51-6
NCGC00256731-01
2-Methoxy-4-methylphenol, >=98%, FG
AS-15967
SY036778
2-Methoxy-4-methylphenol (4-methylguaiacol)
4-Methyl-2-methoxyphenol (4-methylguaiacol)
M0114
NS00012823
2-Methoxy-4-methylphenol, analytical standard
EN300-18155
2-Methoxy-4-methylphenol, natural, 97%, FG
D70655
Q403037
2-Methoxy-p-cresol;Creosol;2-Methoxy-4-methylphenol
Z57234300
F0001-2237