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m-Cresol

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Identification
Molecular formula
C7H8O
CAS number
108-39-4
IUPAC name
2-methoxy-5-methyl-phenol
State
State

At room temperature, m-Cresol is typically encountered as a liquid but can also crystallize in solid form under appropriate conditions (e.g., low temperatures).

Melting point (Celsius)
11.80
Melting point (Kelvin)
284.95
Boiling point (Celsius)
204.50
Boiling point (Kelvin)
477.65
General information
Molecular weight
124.18g/mol
Molar mass
124.1760g/mol
Density
1.0350g/cm3
Appearence

m-Cresol, also known as 3-methylphenol, appears as a colorless to yellow liquid. It can also appear as a crystal with a slight sweet odor, characteristic of phenolic compounds.

Comment on solubility

Solubility of 2-methoxy-5-methyl-phenol

2-methoxy-5-methyl-phenol, also known as guaiacol, exhibits notable characteristics when it comes to its solubility in various solvents. The solubility can be summarized as follows:

  • Solvent Types:
    • Polar solvents: 2-methoxy-5-methyl-phenol is soluble in polar solvents like water, due to the presence of the hydroxyl group (-OH) in its structure.
    • Nonpolar solvents: It also has solubility in nonpolar organic solvents, such as ethyl acetate and hexane, because of its aromatic ring structure.
  • Temperature Dependence: The solubility of 2-methoxy-5-methyl-phenol tends to increase with rising temperatures, which is a common trend for many organic compounds.
  • Concentration: At higher concentrations, precipitation may occur when dissolved in water, indicating its limit of solubility in that medium.

To conclude, the solubility profile of 2-methoxy-5-methyl-phenol is characterized by its ability to dissolve in both polar and nonpolar solvents, making it a versatile compound in various chemical applications. Remember, the solvent choice greatly impacts the effectiveness of dissolution, so it is essential to consider the solvent's properties when working with this compound.

Interesting facts

Interesting Facts about 2-Methoxy-5-Methyl-Phenol

2-Methoxy-5-methyl-phenol, commonly known as orphenadrine, is an intriguing chemical compound with various applications and properties that pique the interest of chemists and students alike. Here are some fascinating aspects of this compound:

  • Natural Occurrence: This compound is related to the structure of certain natural products and can be found in various plant extracts, emphasizing its importance in phytochemistry.
  • Pharmaceutical Applications: 2-Methoxy-5-methyl-phenol is frequently used in pharmacology, particularly for its ability to serve as an active ingredient in medications aimed at treating muscle pain and spasms.
  • Antioxidant Properties: This compound exhibits antioxidant activity, which means it can help neutralize free radicals in biological systems, potentially reducing oxidative stress.
  • Versatile Reactivity: The presence of both the methoxy and methyl groups enhances its reactivity in organic synthesis, making it valuable for creating more complex chemical structures.
  • Importance in Aromatherapy: Due to its pleasant scent, 2-methoxy-5-methyl-phenol is also used in perfumery and aromatherapy applications, adding to its wide-ranging significance.

In conclusion, 2-methoxy-5-methyl-phenol is far more than just a simple aromatic compound. Its various chemical properties and real-world applications illustrate the interconnectedness of chemistry with nature, medicine, and everyday life. Each application and property opens up avenues for further research and exploration within the field of chemistry.

Synonyms
2-Methoxy-5-methylphenol
Isocreosol
Phenol, 2-methoxy-5-methyl-
5-Methylguaiacol
6-Methoxy-m-cresol
2-Hydroxy-4-methylanisole
m-CRESOL, 6-METHOXY-
3-hydroxy-4-methoxytoluene
EINECS 214-791-7
UNII-AV5V76OU33
BRN 1817644
AV5V76OU33
5-methyl-2-methoxyphenol
IFNDEOYXGHGERA-UHFFFAOYSA-
DTXSID70152469
4-06-00-05879 (Beilstein Handbook Reference)
3-HYDROXY-4-METHOXY-1-METHYLBENZENE
DTXCID6074960
ifndeoyxghgera-uhfffaoysa-n
inchi=1/c8h10o2/c1-6-3-4-8(10-2)7(9)5-6/h3-5,9h,1-2h3
1195-09-1
Isocreosole
2-methoxy-5-methyl-phenol
MFCD00040901
m-Creosol
4-methyl-2-hydroxy anisole
ghl.PD_Mitscher_leg0.527
Phenol,2-methoxy-5-methyl-
SCHEMBL218637
CHEBI:194904
CL8467
2-methoxy-5-methylphenol, AldrichCPR
AKOS009158076
CS-W016494
BP-11158
SY037881
TS-01781
DB-021278
H0624
NS00021557
EN300-177729
Q10303982