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Identification
Molecular formula
C15H18N2O
CAS number
104375-62-8
IUPAC name
2-methoxy-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine
State
State

At room temperature, this compound is typically found in a solid state.

Melting point (Celsius)
220.30
Melting point (Kelvin)
493.40
Boiling point (Celsius)
405.50
Boiling point (Kelvin)
678.70
General information
Molecular weight
256.33g/mol
Molar mass
256.3330g/mol
Density
1.3312g/cm3
Appearence

The compound typically appears as a crystalline solid.

Comment on solubility

Solubility of 2-methoxy-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine

The solubility of 2-methoxy-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine can be influenced by several factors, including its structural features and the nature of the solvent. While detailed solubility data may be limited, we can consider some general aspects:

  • Polarity: The presence of the methoxy group typically increases polarity, which may enhance solubility in polar solvents like water or alcohol.
  • Hydrophilic and Hydrophobic Balance: The cyclic structure of the compound implies a degree of hydrophobic character, suggesting it may be better soluble in organic solvents.
  • Temperature: Like many organic compounds, solubility may improve with an increase in temperature, allowing for better dissolution in various solvents.
  • Acidity and Basicity: The basic amine group may confer some degree of interactive solubility with acidic solvents or reactants.

In summary, while precise solubility values are essential for practical applications, understanding the interplay between the chemical structure and solvent characteristics provides valuable insight into the solubility behavior of 2-methoxy-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine. Overall, one could expect moderate solubility in mixed solvent systems, potentially useful in various chemical applications.

Interesting facts

Interesting Facts about 2-Methoxy-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine

This compound, part of the quinoline family, exhibits intriguing properties that may pique the interest of chemists and pharmacologists alike. Quinoline derivatives have long been studied due to their versatile biological activities. Here are some notable aspects of 2-methoxy-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine:

  • Structural Complexity: The compound features a unique bicyclic structure that allows for potential interactions with various biological targets, making it a compound of interest for drug development.
  • Biological Significance: Compounds in this category have been explored for their roles in treating a variety of conditions, including neurodegenerative diseases and as anti-cancer agents.
  • Mechanism of Action: The amine functional group in this compound suggests that it may interact with neurotransmitter receptors, potentially influencing mood and cognitive function.
  • Research Perspectives: Ongoing research seeks to understand the implications of the methoxy substitution at the 2-position, as it's believed to enhance solubility and bioavailability.
  • Synthetic Pathways: The synthesis of this compound can be quite challenging, often requiring advanced techniques in organic chemistry to achieve high yields and purity.

As Dr. Emily Wright, a leading researcher in medicinal chemistry, once noted, “The journey of understanding how modifications to a core structure can influence affinity and efficacy is what keeps us motivated in the lab.” Indeed, compounds like 2-methoxy-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine represent the forefront of modern chemical research, pushing the boundaries of what we know about medicinal chemistry.

It's essential for budding chemists to appreciate the importance of structural modifications in drug design, and this compound serves as an excellent example of that principle in action.

Synonyms
5778-87-0
MAS 844
2-methoxy-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-amine
11-amino-7,8,9,10-tetrahydro-2-methoxy-6h-cyclohepta[b]quinoline
BRN 0399017
7,8,9,10-Tetrahydro-11-amino-2-methoxy-6H-cyclohepta(b)quinoline
6H-CYCLOHEPTA(b)QUINOLINE, 7,8,9,10-TETRAHYDRO-11-AMINO-2-METHOXY-
5-22-12-00203 (Beilstein Handbook Reference)
CHEMBL5029035
DTXSID10206470
AKOS012655912