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Methoxyphenamine

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Identification
Molecular formula
C11H14F3NO
CAS number
1390-12-7
IUPAC name
2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine
State
State

At room temperature, Methoxyphenamine is a liquid, typically volatile with a distinct odor.

Melting point (Celsius)
5.10
Melting point (Kelvin)
278.25
Boiling point (Celsius)
210.20
Boiling point (Kelvin)
483.35
General information
Molecular weight
217.24g/mol
Molar mass
217.2410g/mol
Density
1.1530g/cm3
Appearence

Methoxyphenamine is typically a colorless liquid that may appear slightly yellow.

Comment on solubility

Solubility of 2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine

The solubility of the compound 2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine is an important aspect of its chemical behavior and applications. This compound exhibits a range of solubility characteristics influenced by its molecular structure, particularly due to the presence of various functional groups.

Key Points on Solubility:

  • Polar Nature: The methoxy group (-OCH3) contributes to the overall polarity of the molecule, which can enhance its solubility in polar solvents such as water and alcohol.
  • Hydrophobic Component: The trifluoromethyl group (-CF3) introduces a hydrophobic character, potentially limiting its solubility in polar environments.
  • Solvent Dependence: Solubility is likely to vary significantly between different solvents; for instance, it may be more soluble in organic solvents like dichloromethane than in water.

In summary, the solubility of 2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine can be characterized by its dual nature of being influenced by both polar and non-polar interactions. Therefore, understanding the solvent environment is crucial for predicting its solubility behavior. As a practical reminder, when considering solubility, it’s essential to explore the specific solvent characteristics to determine the most effective dissolution method.

Interesting facts

Interesting Facts about 2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine

This compound is a fascinating member of the amine family, known for its diverse applications in various fields, particularly in medicinal chemistry. Here are some captivating insights into this compound:

  • Structure and Composition: The presence of both a methoxy group and a trifluoromethyl group enhances the molecule's unique characteristics. The combination of these functional groups can significantly influence the compound's reactivity and biological properties.
  • Biological Activity: Compounds similar to this one are often investigated for their potential as pharmaceutical agents. Some derivatives of amines have been noted for their neuropharmacological properties, making this compound a subject of interest in drug discovery.
  • Applications: Besides its medicinal potential, this compound and its derivatives could have applications in organic synthesis and materials science. The design of molecules with specific electronic properties is crucial for developing new materials.
  • Research Grounds: The presence of the trifluoromethyl group is particularly noteworthy since it can impart desirable properties such as increased lipophilicity and metabolic stability, qualities that can be pivotal in drug design.
  • Environmental Impact: Understanding the behavior and impact of trifluoromethyl-containing compounds is increasingly important, as scientists study their environmental persistence and toxicity.

In summary, 2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine is not just a mere chemical entity; it embodies a broader realm of possibilities in scientific research and application. The intricate balance of its structural components highlights the stunning complexity of chemistry and the continuous pursuit of knowledge in the field.

Synonyms
FLUDOREX
15221-81-5
Fludorex [USAN:INN]
UNII-346FQP00BI
Fludorex (USAN)
WIN 11,464
346FQP00BI
FLUDOREX [USAN]
FLUDOREX [INN]
WIN-11464
Benzeneethanamine, .beta.-methoxy-N-methyl-3-(trifluoromethyl)-
beta-Methoxy-N-methyl-m-(trifluoromethyl)phenethylamine
Benzeneethanamine, beta-methoxy-N-methyl-3-(trifluoromethyl)-
.BETA.-METHOXY-N-METHYL-M-(TRIFLUOROMETHYL)PHENETHYLAMINE
2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine
SCHEMBL123129
CHEMBL2103770
DTXSID20864565
CHEBI:177867
CXLOIJUDIPVKOU-UHFFFAOYSA-N
NS00120879
D04205
Q5462629
2-methoxy-N-methyl-2-[3-(triluoromethyl)phenyl]ethanamine
2-Methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethan-1-amine