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Methoxetamine Hydrochloride

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Identification
Molecular formula
C11H15F3NO2 · HCl
CAS number
1239943-33-9
IUPAC name
2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine;hydrochloride
State
State

At room temperature, Methoxetamine Hydrochloride is typically in a solid-state, manifesting as a powder. It is stable under normal conditions, but should be kept in a dry and cool place to prevent degradation. Handling typically requires care to ensure precision and safety due to its fine particulate nature.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
327.76g/mol
Molar mass
292.7660g/mol
Density
1.2120g/cm3
Appearence

At room temperature, Methoxetamine Hydrochloride appears as a fine crystalline powder. It is usually white or off-white in color. The compound is typically available as a powder for ease of handling and measurement. However, due to its hygroscopic nature, it can absorb moisture from the environment, which can clump or slightly change its appearance.

Comment on solubility

Solubility of 2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine; hydrochloride

The solubility of 2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine; hydrochloride is an important consideration in its applications and efficacy. This compound, being a hydrochloride salt, typically exhibits enhanced solubility in polar solvents. Here are some key points regarding its solubility:

  • Polar Solvents: This hydrochloride salt is likely to be quite soluble in water and other polar solvents due to the presence of the ionic hydrochloride group.
  • Non-polar Solvents: Conversely, the solubility in non-polar organic solvents may be significantly lower, potentially limiting its use in certain applications.
  • pH Dependence: The solubility can also be influenced by the pH of the solution; generally, acidic conditions promote the salt form's solubility.
  • Temperature Effects: Increases in temperature often enhance the solubility of many salts, including this compound.

In summary, the solubility of 2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine; hydrochloride is expected to be favorable in polar environments, making it suitable for various chemical processes where solubility plays a critical role.

Interesting facts

Interesting Facts about 2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine; hydrochloride

2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine; hydrochloride, often referred to in scientific literature with its more concise identifiers, is a fascinating compound that basks in the intersection of organic chemistry and pharmacology.

Key Highlights

  • Pharmacological Potential: This compound is notable for its potential use in medicinal chemistry, specifically as a *selective serotonin reuptake inhibitor (SSRI)*. Researchers delve into its mechanism to understand how it may impact mood and anxiety disorders.
  • Trifluoromethyl Group: The presence of the *trifluoromethyl* group is particularly intriguing. It can enhance the compound's lipophilicity, leading to increased bioavailability and effectiveness in therapeutic applications.
  • Substituent Effects: The methoxy and methyl groups in its structure contribute to its *overall molecular behavior,* influencing solubility and biological activity. Such modifications can lead to unique interactions within biological systems.
  • Research-Based Insights: As scientists continue to investigate similar compounds, findings often shed light on their structure-activity relationships, which are vital for drug design. This compound serves as an exemplary model in studies aimed at developing innovative therapies.
  • Synthesis Pathways: The synthesis of this compound involves multi-step organic reactions, showcasing the *craftsmanship* in synthetic organic chemistry. Each step requires precision and meticulous attention to detail for successful outcomes.

In summary, 2-methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethanamine; hydrochloride is a compound that exemplifies the beauty and complexity of chemical research. Its potential therapeutic applications coupled with the unique structural characteristics make it a captivating subject for ongoing studies in chemistry and pharmacology.

Synonyms
BETA-METHOXY-N-METHYL-M-TRIFLUOROMETHYLPHENETHYLAMINE HYDROCHLORIDE
15221-80-4
Phenethylamine, beta-methoxy-N-methyl-m-trifluoromethyl-, hydrochloride
DTXSID70934444
2-Methoxy-N-methyl-2-[3-(trifluoromethyl)phenyl]ethan-1-amine--hydrogen chloride (1/1)