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2-Methoxyacridine

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Identification
Molecular formula
C14H11NO
CAS number
3076-33-1
IUPAC name
2-methoxyacridine
State
State
At room temperature, 2-Methoxyacridine is typically a solid.
Melting point (Celsius)
81.00
Melting point (Kelvin)
354.15
Boiling point (Celsius)
399.00
Boiling point (Kelvin)
672.15
General information
Molecular weight
211.25g/mol
Molar mass
211.2460g/mol
Density
1.2600g/cm3
Appearence

2-Methoxyacridine typically appears as a yellow to orange crystalline solid. It may also have a slight sheen or gloss depending on its form of crystallization.

Comment on solubility

Solubility of 2-methoxyacridine

2-methoxyacridine, with the chemical formula C15H13N1O1, is a compound that exhibits unique solubility characteristics. Understanding the solubility of this compound is important in various applications, and here are some key points:

  • Solvent Preferences: 2-methoxyacridine is generally more soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and acetone. It has limited solubility in polar solvents like water.
  • Temperature Influence: The solubility of this compound can be affected by temperature. Increased temperatures typically increase solubility in organic solvents, which is crucial for practical applications.
  • Polarity Factor: The presence of the methoxy group (-OCH3) contributes to its solubility characteristics, as it can increase the compound's polarity and its interaction with organic solvents.

In summary, while 2-methoxyacridine exhibits limited water solubility, it shows significant solubility in various organic solvents, making it valuable for applications that require organic phase interactions. As always, testing in specific conditions is recommended to determine solubility behaviors accurately!

Interesting facts

Interesting Facts about 2-Methoxyacridine

2-Methoxyacridine is a fascinating heterocyclic compound renowned for its unique structure and diverse applications in various fields. Here are some intriguing facts:

  • Structure and Properties: As a derivative of acridine, 2-methoxyacridine features an aromatic framework with a methoxy group attached to the second position. This modification not only alters its chemical reactivity but also enhances its biological activity.
  • Biological Significance: Compounds like 2-methoxyacridine are often explored for their potential in medicinal chemistry, particularly due to their antitumor and antimicrobial properties. Researchers have noted its activity against a range of pathogens.
  • Role in Organic Synthesis: 2-Methoxyacridine serves as an important intermediate in the synthesis of various organic compounds. Its reactivity allows chemists to create more complex molecules, making it a valuable building block in drug development.
  • Fluorescence Studies: This compound is also studied for its photophysical properties, which can be utilized in fluorescent probes. These probes help in understanding biological processes at a molecular level, paving the way for advanced imaging techniques.
  • Research Insights: As noted by some researchers, "The careful study of methoxy-substituted acridines has revealed their potential vast applications, especially in the pharmaceutical industry." This highlights the importance of compounds like 2-methoxyacridine in the quest for new therapeutic agents.

Overall, 2-methoxyacridine exemplifies the intersection of synthetic chemistry and biological research, showcasing how modifications in chemical structures can lead to enhanced functionalities and wider applications.

Synonyms
ACRIDINE, 2-METHOXY-
3295-60-1
2-methoxyacridine
3-Methoxyacridine (European)
BRN 0010165
2-methoxy acridine
SCHEMBL1527016
DTXSID80186598
NOIQZLIGXCQSEV-UHFFFAOYSA-N